Migration of immature and mature B cells in the aged microenvironment

Immunology

Volumn 129, Issue 2, 2010, Pages 278-290

  Minges Wols, Heather A ^a,b   Johnson, Kara M ^b,c   Ippolito, Jill A ^b   Birjandi, Shirin Z ^b   Su, Yan ^b,d   Le, Phong T ^b   Witte, Pamela L ^b  

^a and Social Sciences   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c ABBOTT DIAGNOSTICS   (United States)

^d HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Aging; B cell; CXCL13; Migration

Indexed keywords

CXCL13 CHEMOKINE; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1;

AGE; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW; CONTROLLED STUDY; FEMALE; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; RETICULUM CELL; SPLEEN;

ADOPTIVE TRANSFER; AGING; ANIMALS; B-LYMPHOCYTE SUBSETS; BONE MARROW; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL MOVEMENT; CHEMOKINE CXCL13; MALE; MICE; MICE, INBRED BALB C; PRECURSOR CELLS, B-LYMPHOID; SPLEEN;

EID: 73949104748     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03182.x     Document Type: Article

References (44)

1. Dorshkind K, Montecino-Rodriguez E, Signer RA. The ageing immune system: is it ever too old to become young again? Nat Rev Immunol 2009 9 : 57 62.
2. Allen CD, Cyster JG. Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function. Semin Immunol 2008 20 : 14 25.
3. Campbell DJ, Kim CH, Butcher EC. Chemokines in the systemic organization of immunity. Immunol Rev 2003 195 : 58 71.
4. Ohl L, Bernhardt G, Pabst O, Forster R. Chemokines as organizers of primary and secondary lymphoid organs. Semin Immunol 2003 15 : 249 255.
5. Cheung HT, Nadakavukaren MJ. Age-dependent changes in the cellularity and ultrastructure of the spleen of Fischer F344 rats. Mech Ageing Dev 1983 22 : 23 33.
6. Eaton-Bassiri AS, Mandik-Nayak L, Seo SJ, Madaio MP, Cancro MP, Erikson J. Alterations in splenic architecture and the localization of anti-double-stranded DNA B cells in aged mice. Int Immunol 2000 12 : 915 926.
7. Holmes KL, Schnizlein CT, Perkins EH, Tew JG. The effect of age on antigen retention in lymphoid follicles and in collagenous tissue of mice. Mech Ageing Dev 1984 25 : 243 255.
8. Sato H, Dobashi M. The distribution, immune complex trapping ability and morphology of follicular dendritic cells in popliteal lymph nodes of aged rats. Histol Histopathol 1998 13 : 99 108.
9. Szakal AK, Aydar Y, Balogh P, Tew JG. Molecular interactions of FDCs with B cells in aging. Semin Immunol 2002 14 : 267 274.
10. Szakal AK, Taylor JK, Smith JP, Kosco MH, Burton GF, Tew JJ. Kinetics of germinal center development in lymph nodes of young and aging immune mice. Anat Rec 1990 227 : 475 485.
11. Zheng B, Han S, Takahashi Y, Kelsoe G. Immunosenescence and germinal center reaction. Immunol Rev 1997 160 : 63 77.
12. Ansel KM, Ngo VN, Hyman PL et al. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 2000 406 : 309 314.
13. Cinamon G, Zachariah MA, Lam OM, Foss FW Jr., Cyster JG. Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat Immunol 2008 9 : 54 62.
14. Gunn MD, Kyuwa S, Tam C, Kakiuchi T, Matsuzawa A, Williams LT, Nakano H. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J Exp Med 1999 189 : 451 460.
15. Johnson KM, Owen K, Witte PL. Aging and developmental transitions in the B cell lineage. Int Immunol 2002 14 : 1313 1323.
16. Kline GH, Hayden TA, Klinman NR. B cell maintenance in aged mice reflects both increased B cell longevity and decreased B cell generation. J Immunol 1999 162 : 3342 3349.
17. Labrie JE III., Sah AP, Allman DM, Cancro MP, Gerstein RM. Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice. J Exp Med 2004 200 : 411 423.
18. Shahaf G, Johnson K, Mehr R. B cell development in aging mice: lessons from mathematical modeling. Int Immunol 2006 18 : 31 9.
19. Allman D, Lindsley RC, DeMuth W, Rudd K, Shinton SA, Hardy RR. Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J Immunol 2001 167 : 6834 6840.
20. Loder F, Mutschler B, Ray RJ, Paige CJ, Sideras P, Torres R, Lamers MC, Carsetti R. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J Exp Med 1999 190 : 75 89.
21. Lortan JE, Roobottom CA, Oldfield S, MacLennan IC. Newly produced virgin B cells migrate to secondary lymphoid organs but their capacity to enter follicles is restricted. Eur J Immunol 1987 17 : 1311 1316.
22. Blaeser A, McGlauchlen K, Vogel LA. Aged B lymphocytes retain their ability to express surface markers but are dysfunctional in their proliferative capability during early activation events. Immun Ageing 2008 5 : 15.
23. Eaton SM, Burns EM, Kusser K, Randall TD, Haynes L. Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses. J Exp Med 2004 200 : 1613 1622.
24. Snow EC. An evaluation of antigen-driven expansion and differentiation of hapten-specific B lymphocytes purified from aged mice. J Immunol 1987 139 : 1758 1762.
25. Yang X, Stedra J, Cerny J. Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice. J Exp Med 1996 183 : 959 970.
26. Frasca D, Van der Put E, Landin AM, Gong D, Riley RL, Blomberg BB. RNA stability of the E2A-encoded transcription factor E47 is lower in splenic activated B cells from aged mice. J Immunol 2005 175 : 6633 6644.
27. King AM, Van der Put E, Blomberg BB, Riley RL. Accelerated Notch-dependent degradation of E47 proteins in aged B cell precursors is associated with increased ERK MAPK activation. J Immunol 2007 178 : 3521 3529.
28. Srivastava B, Quinn WJ III., Hazard K, Erikson J, Allman D. Characterization of marginal zone B cell precursors. J Exp Med 2005 202 : 1225 1234.
29. Won WJ, Foote JB, Odom MR, Pan J, Kearney JF, Davis RS. Fc receptor homolog 3 is a novel immunoregulatory marker of marginal zone and B1 B cells. J Immunol 2006 177 : 6815 6823.
30. Mueller SN, Hosiawa-Meagher KA, Konieczny BT, Sullivan BM, Bachmann MF, Locksley RM, Ahmed R, Matloubian M. Regulation of homeostatic chemokine expression and cell trafficking during immune responses. Science 2007 317 : 670 674.
31. Minges Wols HA, Ippolito JA, Yu Z, Palmer JL, White FA, Le PT, Witte PL. The effects of microenvironment and internal programming on plasma cell survival. Int Immunol 2007 19 : 837 846.
32. Katakai T, Suto H, Sugai M et al. Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J Immunol 2008 181 : 6189 6200.
33. Girkontaite I, Sakk V, Wagner M, Borggrefe T, Tedford K, Chun J, Fischer KD. The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization. J Exp Med 2004 200 : 1491 1501.
34. Riley RL, Van der Put E, King AM, Frasca D, Blomberg BB. Deficient B lymphopoiesis in murine senescence: potential roles for dysregulation of E2A, Pax-5, and STAT5. Semin Immunol 2005 17 : 330 336.
35. Cancro MP. B cells and aging: gauging the interplay of generative, selective, and homeostatic events. Immunol Rev 2005 205 : 48 59.
36. Johnson SA, Cambier JC. Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity. Arthritis Res Ther 2004 6 : 131 139.
37. Miller JP, Cancro MP. B cells and aging: balancing the homeostatic equation. Exp Gerontol 2007 42 : 396 399.
38. Honczarenko M, Douglas RS, Mathias C, Lee B, Ratajczak MZ, Silberstein LE. SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells. Blood 1999 94 : 2990 2998.
39. Pahlavani MA, Richardson A, Cheung HT. Age-dependent changes of the mesenteric lymph node of Fischer F344 rats: morphological and histometric analysis. Mech Ageing Dev 1987 39 : 137 146.
40. Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007 8 : 729 740.
41. Opstelten D, Osmond DG. Regulation of pre-B cell proliferation in bone marrow: immunofluorescence stathmokinetic studies of cytoplasmic mu chain-bearing cells in anti-IgM-treated mice, hematologically deficient mutant mice and mice given sheep red blood cells. Eur J Immunol 1985 15 : 599 605.
42. Cariappa A, Mazo IB, Chase C et al. Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes. Immunity 2005 23 : 397 407.
43. Sapoznikov A, Pewzner-Jung Y, Kalchenko V, Krauthgamer R, Shachar I, Jung S. Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow niches. Nat Immunol 2008 9 : 388 395.
44. Ueda Y, Yang K, Foster SJ, Kondo M, Kelsoe G. Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. J Exp Med 2004 199 : 47 58.