1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway

Chemical Research in Toxicology

Volumn 22, Issue 12, 2009, Pages 1938-1947

  Chu, Wen Cheng ^a   Hong, Wei Fu ^a   Huang, Min Cong ^a   Chen, Fei Yun ^a   Lin, Shin Chang ^a   Liao, Pei Jyuan ^a   Su, Jyan Gwo J ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1 NITROPYRENE; 3 NITROFLUORANTHENE; 6 NITROCHRYSENE; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CHRYSENE; CYTOCHROME P450 1A1; FLUORANTHENE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; PYRENE; PYRENE DERIVATIVE; RESVERATROL; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MUTANT; CELL VIABILITY; CONTROLLED STUDY; GENE CONTROL; GENETIC STABILITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; TRANSACTIVATION; TURNOVER TIME;

ANIMALS; BENZO(A)PYRENE; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; MICE; MUTAGENS; PROTO-ONCOGENE PROTEINS C-AKT; PYRENES; RECEPTORS, ARYL HYDROCARBON; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER;

EID: 73849136268     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900241g     Document Type: Article

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