Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells

Toxicology Letters

Volumn 161, Issue 3, 2006, Pages 236-243

  Cherng, Shur Hueih ^a   Hsu, Shih Lan ^b,c   Yang, Jia Ling ^d   Yu, Chang Tze Ricky ^c   Lee, Huei ^b  

^a HUNGKUANG UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

1 Nitropyrene; Benzo a pyrene; Chemical interaction; CYP1A1; Proteolysis; Transcriptional suppression

Indexed keywords

1 NITROPYRENE; BENZO[A]PYRENE; CYTOCHROME P450 1A1; DITHIOTHREITOL; MESSENGER RNA; REACTIVE OXYGEN METABOLITE;

ARTICLE; CHEMICAL INTERACTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR INTERACTION; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STABILITY; WESTERN BLOTTING;

BENZO(A)PYRENE; CARCINOGENS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; DRUG COMBINATIONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; HUMANS; MICROSOMES, LIVER; MUTAGENS; PYRENES; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 31344458328     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2005.10.002     Document Type: Article

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