Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation

Toxicology

Volumn 235, Issue 1-2, 2007, Pages 62-72

  Chung, Jin Yong ^a   Kim, Ji Young ^a   Kim, Won Rok ^a   Lee, Seung Gee ^a   Kim, Yoon Jae ^a   Park, Ji Eun ^a   Hong, Yeon Pyo ^b   Chun, Young Jin ^b   Park, Young Chul ^c   Oh, Seunghoon ^d   Yoo, Ki Soo ^a   Yoo, Young Hyun ^a   Kim, Jong Min ^a  

^a Dong A University   (South Korea)

^b Chung Ang University   (South Korea)

^c Pusan National University School of Medicine   (South Korea)

^d Dankook University   (South Korea)

Author keywords

AhR; Apoptosis; Benzo a pyrene; CYP1A1; CYP1B1; Hepatoma cells

Indexed keywords

ALPHA NAPHTOFLAVONE; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CASPASE 3; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; ELLIPTICINE; FLAVONE DERIVATIVE; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; APOPTOSIS; ARYL HYDROCARBON HYDROXYLASES; BENZO(A)PYRENE; BENZOFLAVONES; CARCINOGENS; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROME P-450 CYP1A1; DOWN-REGULATION; ELLIPTICINES; ENZYME INDUCTION; ENZYME INHIBITORS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; PHOSPHORYLATION; RECEPTORS, ARYL HYDROCARBON; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34247631090     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.03.013     Document Type: Article

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