Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis

Toxicology

Volumn 244, Issue 2-3, 2008, Pages 257-270

  Su, Jyan Gwo J ^a   Liao, Pei Jyuan ^a   Huang, Min Cong ^a   Chu, Wen Cheng ^a   Lin, Shin Chang ^a   Chang, Yu Jung ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

1 Nitropyrene; Aldo keto reductase; Apoptosis; Cytochrome P450; p53

Indexed keywords

1 NITROPYRENE; 1,10 PHENANTHROLINE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALDOKETOREDUCTASE 1C1; ALDOKETOREDUCTASE 1C2; ALDOKETOREDUCTASE 1C4; ALDOKETOREDUCTASE 7A1; ALDOKETOREDUCTASE 7A5; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BENZO[A]PYRENE; CITRIC ACID; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B; ELLIPTICINE; ENZYME; HOE 33342; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITROBENZENE; NITROMETHANE; PHOSPHATIDYLSERINE; PROPOFOL; PROTEIN P53; SUCCINIC ACID; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ALCOHOL OXIDOREDUCTASES; APOPTOSIS; BENZIMIDAZOLES; BENZO(A)PYRENE; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; FLOW CYTOMETRY; FLUORESCENT DYES; HUMANS; ISOENZYMES; LUCIFERASES; MUTAGENS; PHOSPHORYLATION; PLASMIDS; POLYCYCLIC HYDROCARBONS, AROMATIC; PYRENES; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 38749087578     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.11.022     Document Type: Article

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