메뉴 건너뛰기




Volumn 192, Issue 2, 2010, Pages 169-178

The effect of midazolam on mouse Leydig cell steroidogenesis and apoptosis

Author keywords

3 HSD; Cell death; Flumazenil (Anexate ); Leydig cell; Midazolam (Dormicum ); P450scc; PBR; PKA; PKC; StAR; Steroidogenesis

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; BENZODIAZEPINE RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; FLUMAZENIL; MIDAZOLAM MALEATE; PROTEIN KINASE C;

EID: 73749086960     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.10.017     Document Type: Article
Times cited : (23)

References (51)
  • 2
    • 0030459652 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: implications for the mechanism of StAR action
    • Arakane F., Sugawara T., Nishino H., Liu Z., Holt J., Pain D., Stocco D., Miller W., and Strauss J. Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: implications for the mechanism of StAR action. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 13731-13736
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 13731-13736
    • Arakane, F.1    Sugawara, T.2    Nishino, H.3    Liu, Z.4    Holt, J.5    Pain, D.6    Stocco, D.7    Miller, W.8    Strauss, J.9
  • 3
    • 0019364734 scopus 로고
    • Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses
    • Ascoli M. Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses. Endocrinology 108 (1981) 88-95
    • (1981) Endocrinology , vol.108 , pp. 88-95
    • Ascoli, M.1
  • 4
    • 0032401018 scopus 로고    scopus 로고
    • Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes
    • Bender A.S., and Norenberg M.D. Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes. J. Neurosci. Res. 54 (1998) 673-680
    • (1998) J. Neurosci. Res. , vol.54 , pp. 673-680
    • Bender, A.S.1    Norenberg, M.D.2
  • 5
    • 0030445907 scopus 로고    scopus 로고
    • Acute action of choriogonadotropin on MA-10 tumor cells: changes in the topography of the mitochondrial peripheral-type benzodiazepine receptor
    • Boujrad N., Vidic B., and Papadopoulos V. Acute action of choriogonadotropin on MA-10 tumor cells: changes in the topography of the mitochondrial peripheral-type benzodiazepine receptor. Endocrinology 137 (1996) 5727-5730
    • (1996) Endocrinology , vol.137 , pp. 5727-5730
    • Boujrad, N.1    Vidic, B.2    Papadopoulos, V.3
  • 7
    • 4644346485 scopus 로고    scopus 로고
    • Cordyceps sinensis mycelium activates PKA and PKC signal pathways to stimulate steroidogenesis in MA-10 mouse Leydig tumor cells
    • Chen Y.C., Huang Y.L., and Huang B.M. Cordyceps sinensis mycelium activates PKA and PKC signal pathways to stimulate steroidogenesis in MA-10 mouse Leydig tumor cells. Int. J. Biochem. Cell Biol. 37 (2005) 214-223
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 214-223
    • Chen, Y.C.1    Huang, Y.L.2    Huang, B.M.3
  • 8
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival. Modications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot F., and Lang R. Rapid colorimetric assay for cell growth and survival. Modications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods 89 (1986) 271-277
    • (1986) J. Immunol. Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 11
    • 38049037834 scopus 로고    scopus 로고
    • Basic concepts and recent developments in human steroid hormone biosynthesis
    • Ghayee H.K., and Auchus R.J. Basic concepts and recent developments in human steroid hormone biosynthesis. Rev. Endocr. Metab. Disord. 8 (2007) 289-300
    • (2007) Rev. Endocr. Metab. Disord. , vol.8 , pp. 289-300
    • Ghayee, H.K.1    Auchus, R.J.2
  • 12
    • 0035834279 scopus 로고    scopus 로고
    • Molecular steps of death receptor and mitochondrial pathways of apoptosis
    • Gupta S. Molecular steps of death receptor and mitochondrial pathways of apoptosis. Life Sci. 69 (2001) 2957-2964
    • (2001) Life Sci. , vol.69 , pp. 2957-2964
    • Gupta, S.1
  • 13
    • 0025270280 scopus 로고
    • Propofol for long-term sedation in the intensive care unit. A comparison with papaveretum and midazolam
    • Harris C.E., Grounds R.M., Murray A.M., Lumley J., Royston D., and Morgan M. Propofol for long-term sedation in the intensive care unit. A comparison with papaveretum and midazolam. Anesthesia 45 (1990) 366-372
    • (1990) Anesthesia , vol.45 , pp. 366-372
    • Harris, C.E.1    Grounds, R.M.2    Murray, A.M.3    Lumley, J.4    Royston, D.5    Morgan, M.6
  • 14
    • 20844451376 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria
    • Hauet T., Yao Z.X., Bose H.S., Wall C.T., Han Z., Li W., Hales D.B., Miller W.L., Culty M., and Papadopoulos V. Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria. Mol. Endocrinol. 19 (2005) 540-554
    • (2005) Mol. Endocrinol. , vol.19 , pp. 540-554
    • Hauet, T.1    Yao, Z.X.2    Bose, H.S.3    Wall, C.T.4    Han, Z.5    Li, W.6    Hales, D.B.7    Miller, W.L.8    Culty, M.9    Papadopoulos, V.10
  • 15
    • 0024713760 scopus 로고
    • Effect of the benzodiazepines diazepam, des-N-methyldiazepam and midazolam on corticosteroid biosynthesis in bovine adrenocortical cells in vitro; location of site of action
    • Holloway C.D., Kenyon C.J., Dowie L.J., Corrie J.E., Gray C.E., and Fraser R. Effect of the benzodiazepines diazepam, des-N-methyldiazepam and midazolam on corticosteroid biosynthesis in bovine adrenocortical cells in vitro; location of site of action. J. Steroid Biochem. 33 (1989) 219-225
    • (1989) J. Steroid Biochem. , vol.33 , pp. 219-225
    • Holloway, C.D.1    Kenyon, C.J.2    Dowie, L.J.3    Corrie, J.E.4    Gray, C.E.5    Fraser, R.6
  • 16
    • 0037066401 scopus 로고    scopus 로고
    • Concentration dependency in lead-inhibited steroidogenesis in MA-10 mouse Leydig tumor cells
    • Huang B.M., Lai H.Y., and Liu M.Y. Concentration dependency in lead-inhibited steroidogenesis in MA-10 mouse Leydig tumor cells. J. Toxicol. Environ. Health A 65 (2002) 557-567
    • (2002) J. Toxicol. Environ. Health A , vol.65 , pp. 557-567
    • Huang, B.M.1    Lai, H.Y.2    Liu, M.Y.3
  • 17
    • 22544470581 scopus 로고    scopus 로고
    • Involvement of protein kinase C and cyclic adenosine 3′,5′-monophosphate-dependent kinase in steroidogenic acute regulatory protein expression and steroid biosynthesis in Leydig cells
    • Jo Y., King S.R., Khan S.A., and Stocco D.M. Involvement of protein kinase C and cyclic adenosine 3′,5′-monophosphate-dependent kinase in steroidogenic acute regulatory protein expression and steroid biosynthesis in Leydig cells. Biol. Reprod. 73 (2005) 244-255
    • (2005) Biol. Reprod. , vol.73 , pp. 244-255
    • Jo, Y.1    King, S.R.2    Khan, S.A.3    Stocco, D.M.4
  • 18
    • 0025073860 scopus 로고
    • Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells
    • Krueger K., and Papadopoulos V. Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells. J. Biol. Chem. 265 (1990) 15015-15022
    • (1990) J. Biol. Chem. , vol.265 , pp. 15015-15022
    • Krueger, K.1    Papadopoulos, V.2
  • 19
  • 21
    • 34247377842 scopus 로고    scopus 로고
    • Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling
    • Manna P.R., Jo Y., and Stocco D.M. Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling. J. Endocrinol. 193 (2007) 53-63
    • (2007) J. Endocrinol. , vol.193 , pp. 53-63
    • Manna, P.R.1    Jo, Y.2    Stocco, D.M.3
  • 22
    • 0033058928 scopus 로고    scopus 로고
    • Functional assessment of the calcium messenger system in cultured mouse Leydig tumor cells: regulation of human chorionic gonadotropin-induced expression of the steroidogenic acute regulatory protein
    • Manna P.R., Pakarinen P., El-hefnawy T., and Huhtaniemi I.T. Functional assessment of the calcium messenger system in cultured mouse Leydig tumor cells: regulation of human chorionic gonadotropin-induced expression of the steroidogenic acute regulatory protein. Endocrinology 140 (1999) 1739-1751
    • (1999) Endocrinology , vol.140 , pp. 1739-1751
    • Manna, P.R.1    Pakarinen, P.2    El-hefnawy, T.3    Huhtaniemi, I.T.4
  • 23
    • 33847222701 scopus 로고    scopus 로고
    • Use of anesthetic agents in neonates and young children
    • Mellon R.D., Simone A.F., and Rappaport B.A. Use of anesthetic agents in neonates and young children. Anesth. Analg. 104 (2007) 509-520
    • (2007) Anesth. Analg. , vol.104 , pp. 509-520
    • Mellon, R.D.1    Simone, A.F.2    Rappaport, B.A.3
  • 24
    • 33847041060 scopus 로고    scopus 로고
    • Mechanism of StAR's regulation of mitochondrial cholesterol import
    • Miller W.L. Mechanism of StAR's regulation of mitochondrial cholesterol import. Mol. Cell. Endocrinol. 265-266 (2007) 46-50
    • (2007) Mol. Cell. Endocrinol. , vol.265-266 , pp. 46-50
    • Miller, W.L.1
  • 26
    • 42249095115 scopus 로고    scopus 로고
    • Early exposure to general anesthesia causes significant neuronal deletion in the developing rat brain
    • Nikizad H., Yon J.H., Carter L.B., and Jevtovic-Todorovic V. Early exposure to general anesthesia causes significant neuronal deletion in the developing rat brain. Ann. N.Y. Acad. Sci. 1122 (2007) 69-82
    • (2007) Ann. N.Y. Acad. Sci. , vol.1122 , pp. 69-82
    • Nikizad, H.1    Yon, J.H.2    Carter, L.B.3    Jevtovic-Todorovic, V.4
  • 27
    • 8444230050 scopus 로고    scopus 로고
    • Dose-finding study of intravenous midazolam for seation and amnesia during spinal anesthesia in patients premedicated with intramuscular midazolam
    • Nishiyama T. Dose-finding study of intravenous midazolam for seation and amnesia during spinal anesthesia in patients premedicated with intramuscular midazolam. J. Anesth. 18 (2004) 257-261
    • (2004) J. Anesth. , vol.18 , pp. 257-261
    • Nishiyama, T.1
  • 28
    • 0015589615 scopus 로고
    • Endocrine responses to anaesthetic agents
    • Oyama T. Endocrine responses to anaesthetic agents. Brit. J. Anesth. 45 (1973) 276-281
    • (1973) Brit. J. Anesth. , vol.45 , pp. 276-281
    • Oyama, T.1
  • 29
    • 0029026911 scopus 로고
    • Role of the peripheral-type benzodiazepine receptor and the polypeptide diazepam binding inhibitor in steroidogenesis
    • Papadopoulos V., and Brown A.S. Role of the peripheral-type benzodiazepine receptor and the polypeptide diazepam binding inhibitor in steroidogenesis. J. Steroid Biochem. Mol. Biol. 53 (1995) 103-110
    • (1995) J. Steroid Biochem. Mol. Biol. , vol.53 , pp. 103-110
    • Papadopoulos, V.1    Brown, A.S.2
  • 30
    • 33847039156 scopus 로고    scopus 로고
    • Is there a mitochondrial signaling complex facilitating cholesterol import?
    • Papadopoulos V., Liu J., and Culty M. Is there a mitochondrial signaling complex facilitating cholesterol import?. Mol. Cell. Endocrinol. 265-266 (2007) 59-64
    • (2007) Mol. Cell. Endocrinol. , vol.265-266 , pp. 59-64
    • Papadopoulos, V.1    Liu, J.2    Culty, M.3
  • 31
    • 12844262879 scopus 로고    scopus 로고
    • Regulatory mechanism of Toona sinensis on mouse Leydig cell steroidogenesis
    • Poon S.L., Leu S.F., Hsu H.K., Liu M.Y., and Huang B.M. Regulatory mechanism of Toona sinensis on mouse Leydig cell steroidogenesis. Life Sci. 76 (2005) 1473-1487
    • (2005) Life Sci. , vol.76 , pp. 1473-1487
    • Poon, S.L.1    Leu, S.F.2    Hsu, H.K.3    Liu, M.Y.4    Huang, B.M.5
  • 32
    • 0036939814 scopus 로고    scopus 로고
    • Regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of the cholesterol transfer proteins StAR and PBR
    • Rao R.M., Jo Y., Babb-Tarbox M., Syapin P.J., and Stocco D.M. Regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of the cholesterol transfer proteins StAR and PBR. Endocr. Res. 28 (2002) 387-394
    • (2002) Endocr. Res. , vol.28 , pp. 387-394
    • Rao, R.M.1    Jo, Y.2    Babb-Tarbox, M.3    Syapin, P.J.4    Stocco, D.M.5
  • 34
    • 0031669307 scopus 로고    scopus 로고
    • Inducible expression of protein kinase Ca suppresses steroidogenesis in Y-1 adrenocortical cells
    • Reyland M.E., Williams D.L., and White E.K. Inducible expression of protein kinase Ca suppresses steroidogenesis in Y-1 adrenocortical cells. Am. J. Physiol. 275 (1998) C780-C789
    • (1998) Am. J. Physiol. , vol.275
    • Reyland, M.E.1    Williams, D.L.2    White, E.K.3
  • 35
    • 33748575309 scopus 로고    scopus 로고
    • Diazepam administration prevents testosterone decrease and lipofuscin accumulation in testis of mouse exposed to chronic noise stress
    • Ruffoli R., Carpi A., Giambelluca M.A., Grasso L., Scavuzzo M.C., and Giannessi F.F. Diazepam administration prevents testosterone decrease and lipofuscin accumulation in testis of mouse exposed to chronic noise stress. Andrologia 38 (2006) 159-165
    • (2006) Andrologia , vol.38 , pp. 159-165
    • Ruffoli, R.1    Carpi, A.2    Giambelluca, M.A.3    Grasso, L.4    Scavuzzo, M.C.5    Giannessi, F.F.6
  • 36
    • 0023090998 scopus 로고
    • Reversal of midazolam sedation with anexate
    • Sage D.J., Close A., and Boas R.A. Reversal of midazolam sedation with anexate. Br. J. Anaesth. 59 (1987) 459-464
    • (1987) Br. J. Anaesth. , vol.59 , pp. 459-464
    • Sage, D.J.1    Close, A.2    Boas, R.A.3
  • 38
    • 0033053923 scopus 로고    scopus 로고
    • An update on the mechanism of action of the steroidogenic acute regulatory (StAR) protein
    • Stocco D.M. An update on the mechanism of action of the steroidogenic acute regulatory (StAR) protein. Exp. Clin. Endocrinol. Diabetes 107 (1999) 229-235
    • (1999) Exp. Clin. Endocrinol. Diabetes , vol.107 , pp. 229-235
    • Stocco, D.M.1
  • 39
    • 0034091417 scopus 로고    scopus 로고
    • StARTing to understand cholesterol transfer
    • Stocco D.M. StARTing to understand cholesterol transfer. Nat. Struct. Biol. 7 (2000) 445-447
    • (2000) Nat. Struct. Biol. , vol.7 , pp. 445-447
    • Stocco, D.M.1
  • 40
    • 0030047248 scopus 로고    scopus 로고
    • Regulation of the acute production of steroids in steroidogenic cells
    • Stocco D.M., and Clark B.J. Regulation of the acute production of steroids in steroidogenic cells. Endocr. Rev. 17 (1996) 221-244
    • (1996) Endocr. Rev. , vol.17 , pp. 221-244
    • Stocco, D.M.1    Clark, B.J.2
  • 41
    • 0029153144 scopus 로고
    • Chronic subarachnoid midazolam (Dormicum) in the rat. Morphologic evidence of spinal cord neurotoxicity
    • Svensson B.A., Welin M., Gordh Jr. T., and Westman J. Chronic subarachnoid midazolam (Dormicum) in the rat. Morphologic evidence of spinal cord neurotoxicity. Reg. Anesth. 20 (1995) 426-434
    • (1995) Reg. Anesth. , vol.20 , pp. 426-434
    • Svensson, B.A.1    Welin, M.2    Gordh Jr., T.3    Westman, J.4
  • 42
    • 0026732071 scopus 로고
    • Inhibition of bovine adrenocortical steroidogenesis by benzodiazepines: a direct effect on microsomal hydroxylation or an inhibition of calcium uptake?
    • Thomson I., Fraser R., and Kenyon C.J. Inhibition of bovine adrenocortical steroidogenesis by benzodiazepines: a direct effect on microsomal hydroxylation or an inhibition of calcium uptake?. J. Endocrinol. 135 (1992) 361-369
    • (1992) J. Endocrinol. , vol.135 , pp. 361-369
    • Thomson, I.1    Fraser, R.2    Kenyon, C.J.3
  • 43
    • 0029021964 scopus 로고
    • Regulation of adrenocortical steroidogenesis by benzodiazepines
    • Thomson I., Fraser R., and Kenyon C.J. Regulation of adrenocortical steroidogenesis by benzodiazepines. J. Steroid Biochem. Mol. Biol. 53 (1995) 75-79
    • (1995) J. Steroid Biochem. Mol. Biol. , vol.53 , pp. 75-79
    • Thomson, I.1    Fraser, R.2    Kenyon, C.J.3
  • 44
    • 33646427447 scopus 로고    scopus 로고
    • The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development
    • Veenman L., and Gavish M. The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development. Pharmacol. Ther. 110 (2006) 503-524
    • (2006) Pharmacol. Ther. , vol.110 , pp. 503-524
    • Veenman, L.1    Gavish, M.2
  • 45
    • 34548238745 scopus 로고    scopus 로고
    • Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response
    • Veenman L., Papadopoulos V., and Gavish M. Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response. Curr. Pharm. Des. 13 (2007) 2385-2405
    • (2007) Curr. Pharm. Des. , vol.13 , pp. 2385-2405
    • Veenman, L.1    Papadopoulos, V.2    Gavish, M.3
  • 46
    • 0017139890 scopus 로고
    • Quinazolines and 1,4-benzodiazepines. 75. 7-Hydroxyaminobenzodiazepines and derivatives
    • Walser A., Zenchoff G., and Fryer R.I. Quinazolines and 1,4-benzodiazepines. 75. 7-Hydroxyaminobenzodiazepines and derivatives. J. Med. Chem. 19 (1976) 1378-1381
    • (1976) J. Med. Chem. , vol.19 , pp. 1378-1381
    • Walser, A.1    Zenchoff, G.2    Fryer, R.I.3
  • 48
    • 34548044674 scopus 로고    scopus 로고
    • Sedation in patients above 60 years of age undergoing urological surgery under spinal anesthesia: comparison of propofol and midazolam infusions
    • Yaddanapudi S., Batra Y.K., Balagopal A., and Nagdeve N.G. Sedation in patients above 60 years of age undergoing urological surgery under spinal anesthesia: comparison of propofol and midazolam infusions. J. Postgrad. Med. 53 (2007) 171-175
    • (2007) J. Postgrad. Med. , vol.53 , pp. 171-175
    • Yaddanapudi, S.1    Batra, Y.K.2    Balagopal, A.3    Nagdeve, N.G.4
  • 49
    • 57649210470 scopus 로고    scopus 로고
    • Midazolam dose for loss of response to verbral stimulation during the unilateral or bilateral spinal anesthesia
    • Yun M.J., Kim Y.H., Oh A.Y., Jeon Y.T., and Kim Y.C. Midazolam dose for loss of response to verbral stimulation during the unilateral or bilateral spinal anesthesia. Acta Anaesthesiol. Scand. 53 (2009) 93-97
    • (2009) Acta Anaesthesiol. Scand. , vol.53 , pp. 93-97
    • Yun, M.J.1    Kim, Y.H.2    Oh, A.Y.3    Jeon, Y.T.4    Kim, Y.C.5
  • 50
    • 0032954039 scopus 로고    scopus 로고
    • Developmental expression of the peripheral-type benzodiazepine receptor and the advent of steroidogenesis in rat adrenal glands
    • Zilz A., Li H., Castello R., Papadopoulos V., and Widmaier E.P. Developmental expression of the peripheral-type benzodiazepine receptor and the advent of steroidogenesis in rat adrenal glands. Endocrinology 140 (1999) 859-864
    • (1999) Endocrinology , vol.140 , pp. 859-864
    • Zilz, A.1    Li, H.2    Castello, R.3    Papadopoulos, V.4    Widmaier, E.P.5
  • 51
    • 0025079398 scopus 로고
    • Flumazenil (Anexate): an antagonist of benzodiazepines. Its pharmacopsychologic significance and role in traffic medicine
    • Zimmer G., and Joachim H. Flumazenil (Anexate): an antagonist of benzodiazepines. Its pharmacopsychologic significance and role in traffic medicine. Beitr. Gerichtl. Med. 48 (1990) 409-412
    • (1990) Beitr. Gerichtl. Med. , vol.48 , pp. 409-412
    • Zimmer, G.1    Joachim, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.