Regulatory mechanism of Toona sinensis on mouse leydig cell steroidogenesis

Life Sciences

Volumn 76, Issue 13, 2005, Pages 1473-1487

  Ling Poon, Song ^a   Leu, Sew Fen ^b   Hsu, Hseng Kuang ^c   Liu, Ming Yie ^a   Huang, Bu Miin ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b National Science Council   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Leydig cell; PKA; Regulation; Steroidogenesis; Toona sinensis

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANTINEOPLASTIC AGENT; BUCLADESINE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHORIONIC GONADOTROPIN; CYCLIC AMP; FORSKOLIN; OXYGENASE; PLANT EXTRACT; STEROID 17ALPHA MONOOXYGENASE; STEROID 20ALPHA HYDROXYLASE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; TOONA SINENSIS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; GEOGRAPHIC DISTRIBUTION; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; LEYDIG CELL; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; REGULATORY MECHANISM; SPERMATOZOON MOTILITY; STATISTICAL SIGNIFICANCE; STEROIDOGENESIS; TESTOSTERONE RELEASE; TOONA SINENSIS;

17-ALPHA-HYDROXYPROGESTERONE; ANDROSTENEDIONE; ANIMALS; BUCLADESINE; CELLS, CULTURED; CHORIONIC GONADOTROPIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; HYDROXYCHOLESTEROLS; LEYDIG CELLS; MALE; MELIACEAE; MICE; MICE, INBRED C57BL; PLANT EXTRACTS; PLANT LEAVES; PROGESTERONE; RADIOIMMUNOASSAY; STEROIDS; STIMULATION, CHEMICAL; TESTOSTERONE;

TOONA; TOONA SINENSIS;

EID: 12844262879     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.08.026     Document Type: Article

References (20)

1. F. Beuschlein, C.E. Keegan, D.L. Bavers, C. Mutch, J.E. Hutz, S. Shah, Y.M. Ulrich-Lai, W.C. Engeland, B. Jeffs, J.L. Jameson, and G.D. Hammer SF-1, Dax-1 and acd: molecular determinants of adrenocortical growth and steroidogenesis Endocrine Research 28 4 2002 597 607
2. H.S. Chang, W.C. Hung, M.S. Huang, and H.K. Hsu Extract from the leaves of Toona sinensis roemor exerts potent antiproliferative effect on human lung cancer cells The American Journal of Chinese Medicine 30 2-3 2002 307 314
3. J.M. Edmonds, and M. Staniforth Toona sinensis Curtis's Botanical Magazine 15 3 1998 186 193
4. C.C. Hsu, S.J. Tsai, Y.L. Huang, and B.M. Huang Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis FEBS Letters 543 1-3 2003 140 143
5. H.K. Hsu, Y.C. Yang, J.H. Hwang, and S.J. Hong Effects of Toona sinensis leaf extract on lipolysis in differentiated 3T3-L1 adipocytes Kaoshiung Journal of Medicine Science 19 8 2003 3855 3890
6. B.M. Huang, D.M. Stocco, J.C. Hutson, and R.L. Norman Corticotropin-releasing hormone (CRH) stimulates steroidogenesis in mouse Leydig cells Biology of Reproduction 53 3 1995 620 626
7. B.M. Huang, D.M. Stocco, J.C. Hutson, and R.L. Norman The cellular mechanisms of corticotropin-releasing hormone (CRH) stimulated steroidogenesis in mouse Leydig cells are similar to those of LH Journal of Andrology 18 5 1997 528 534
8. W.L. Miller Early steps in androgen biosynthesis: from cholesterol to DHEA Bailliere's Clinical Endocrinology and Metabolism 12 1 1998 67 81
9. W.H. Moger Evidence for compartmentalization of adenosine 3',5'-monophosphate (cAMP)-dependent protein kinase in rat Leydig cells using site-selective cAMP analogs Endocrinology 128 3 1991 1414 1418
10. L.I. Perry Medical plants of east and southeast Asia: attributed properties and uses Cambridge, Mass 1980 263
11. J.M. Saez Leydig cells: endocrine, paracrine, and autocrine regulation Endocrine Review 15 5 1994 574 626
12. D.M. Stocco, and B.J. Clark Regulation of the acute production of steroids in steroidogenic cells Endocrine Review 17 3 1996 221 224
13. D.M. Stocco The role of the StAR protein in steroidogenesis: challenge for the future Journal of Endocrinology 164 3 2000 247 253
14. D.M. Stocco StAR protein and the regulation of steroid hormone biosynthesis Annual Review of Physiology 63 2001 193 213
15. G.A. Stuart Chinese materia medica-vegetable kingdom Shanghai 1911 100
16. J.J. Tremblay, and R.S. Viger Novel roles for GATA transcription factors in the regulation of steroidogenesis The Journal of Steroid Biochemistry and Molecular Biology 85 2-5 2003 291 298
17. C.S. Wu, S.F. Leu, H.Y. Yang, and B.M. Huang Melatonin inhibits the expression of the steroidogenic acute regulatory protein and steroidogenisis in MA-10 cells Journal of Andrology 22 2 2001 245 254
18. Yang, F.Y., 2003. Study on the physiological functions of Toona sinensis Roem in human spermatozoa. Master thesis in National Cheng Kung University, Taiwan, Tainan, ROC.
19. Y.C. Yang, H.K. Hsu, J.H. Hwang, and S.J. Hong Enhancement of glucose uptake in 3T3-L1 adipocytes by Toona sinensis leaf extract Kaoshiung Journal of Medicine Science 9 7 2003 327 333
20. J.Y.L. Yu Toona sinensis extract affects gene expression of GLUT4 GLU00 se transporter in adipose tissue of alloxan-induced diabetic rats Proceedings of 5th Congress of the International Diabetic Society, May 4-7, 2002, China 2002