메뉴 건너뛰기




Volumn 275, Issue 3 44-3, 1998, Pages

Inducible expression of protein kinase Cα suppresses steroidogenesis in Y-1 adrenocortical cells

Author keywords

Adenosine 3',5'cyclic monophosphate regulation; Cholesterol side chain cleavage; Transcription

Indexed keywords

25 HYDROXYCHOLESTEROL; 8 BROMO CYCLIC AMP; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; PREGNENOLONE; PROTEIN KINASE C; STEROID; TETRACYCLINE;

EID: 0031669307     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.275.3.c780     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 0028169740 scopus 로고
    • Overproduction of a Ca(2+)-independent protein kinase C isozyme, nPKCε, increases the secretion of prolactin from thyrotropin-releasing hormone-stimulated rat pituitary GH4C1 cells
    • Akita, Y., S. Ohno, Y. Yajima, T. Saido, K. Mizuno, K. Chida, S. Osada, T. Kuroki, and S. Kawashima. Overproduction of a Ca(2+)-independent protein kinase C isozyme, nPKCε, increases the secretion of prolactin from thyrotropin-releasing hormone-stimulated rat pituitary GH4C1 cells. J. Biol. Chem. 269: 4653-4660, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4653-4660
    • Akita, Y.1    Ohno, S.2    Yajima, Y.3    Saido, T.4    Mizuno, K.5    Chida, K.6    Osada, S.7    Kuroki, T.8    Kawashima, S.9
  • 2
    • 0025029777 scopus 로고
    • Reporter genes: Application to the study of mammalian gene transcription
    • Alam, J., and J. Cook. Reporter genes: application to the study of mammalian gene transcription. Anal. Biochem. 188: 245-254, 1990.
    • (1990) Anal. Biochem. , vol.188 , pp. 245-254
    • Alam, J.1    Cook, J.2
  • 3
    • 0024276523 scopus 로고
    • The jun proto-oncogene is positively autoregulated by its product, Jun/ AP-1
    • Angel, P., K. Hattori, T. Smeal, and M. Karin. The jun proto-oncogene is positively autoregulated by its product, Jun/ AP-1. Cell 55: 875-885, 1988.
    • (1988) Cell , vol.55 , pp. 875-885
    • Angel, P.1    Hattori, K.2    Smeal, T.3    Karin, M.4
  • 4
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
    • Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49: 729-739, 1987.
    • (1987) Cell , vol.49 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 6
    • 0023043295 scopus 로고
    • Protein kinase C activation by diacylglycerol second messengers
    • Bell, R. M. Protein kinase C activation by diacylglycerol second messengers. Cell 45: 631-632, 1986.
    • (1986) Cell , vol.45 , pp. 631-632
    • Bell, R.M.1
  • 7
    • 0029922644 scopus 로고    scopus 로고
    • Differential control of 17α-hydroxylase and 3β-hydroxysteroid dehydrogenase expression in human adrenocortical H295R cells
    • Bird, I. M., M. M. Pasquarette, W. E. Rainey, and J. I. Mason. Differential control of 17α-hydroxylase and 3β-hydroxysteroid dehydrogenase expression in human adrenocortical H295R cells. J. Clin. Endocrinol. Metab. 81: 2171-2178, 1996.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 2171-2178
    • Bird, I.M.1    Pasquarette, M.M.2    Rainey, W.E.3    Mason, J.I.4
  • 8
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quanities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quanities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254, 1976.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 9
    • 0026465143 scopus 로고
    • Phorbol ester activation of the protein kinase C pathway inhibits gonadotropin-releasing hormone gene expression
    • Bruder, J. M., W. D. Krebs, T. M. Nett, and M. E. Wierman. Phorbol ester activation of the protein kinase C pathway inhibits gonadotropin-releasing hormone gene expression. Endocrinology 131: 2552-2558, 1992.
    • (1992) Endocrinology , vol.131 , pp. 2552-2558
    • Bruder, J.M.1    Krebs, W.D.2    Nett, T.M.3    Wierman, M.E.4
  • 10
    • 0023887047 scopus 로고
    • The phosphatidylcholine pathway of diacylglycerol formation stimulated by phorbol diesters occurs via phospholipase D activation
    • Cabot, M., C. Welsh, H. Cao, and H. Chabbott. The phosphatidylcholine pathway of diacylglycerol formation stimulated by phorbol diesters occurs via phospholipase D activation. FEBS Lett. 233:153-157, 1988.
    • (1988) FEBS Lett. , vol.233 , pp. 153-157
    • Cabot, M.1    Welsh, C.2    Cao, H.3    Chabbott, H.4
  • 13
    • 0030016179 scopus 로고    scopus 로고
    • The c-Jun delta domain inhibits neuroendocrine promoter activity in a DNA sequence and pituitary-specific manner
    • Farrow, K. N., N. Manning, F. Schaufele, and A. Gutierrez-Hartman. The c-Jun delta domain inhibits neuroendocrine promoter activity in a DNA sequence and pituitary-specific manner. J. Biol. Chem. 271:17139-17146, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17139-17146
    • Farrow, K.N.1    Manning, N.2    Schaufele, F.3    Gutierrez-Hartman, A.4
  • 14
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen, M., and H. Bujard. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89:5547-5551, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 15
    • 0029417224 scopus 로고
    • Overexpression of epsilon-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth
    • Hundle, B., T. McMahon, J. Dadgar, and R. O. Messing. Overexpression of epsilon-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth. J. Biol. Chem. 270: 30134-30140, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30134-30140
    • Hundle, B.1    McMahon, T.2    Dadgar, J.3    Messing, R.O.4
  • 16
    • 0025908208 scopus 로고
    • Interaction of phorbol ester and adrenocorticotropin in the regulation of steroidogenic p450 genes in human fetal and adult adrenal cell cultures
    • Ilvesmaki, V., and R. Voutilainen. Interaction of phorbol ester and adrenocorticotropin in the regulation of steroidogenic p450 genes in human fetal and adult adrenal cell cultures. Endocrinology 128:1450-1458, 1991.
    • (1991) Endocrinology , vol.128 , pp. 1450-1458
    • Ilvesmaki, V.1    Voutilainen, R.2
  • 17
    • 0025158107 scopus 로고
    • Protein kinase recognition sequence motifs
    • Kemp, B. E., and R. B. Pearson. Protein kinase recognition sequence motifs. Trends Biochem. Sci. 15:342-346, 1990.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 342-346
    • Kemp, B.E.1    Pearson, R.B.2
  • 18
    • 0014349408 scopus 로고
    • Adrenal cells in tissue culture
    • Kowal, J., and R. Fiedler. Adrenal cells in tissue culture. Arch. Biochem. Biophys. 128:406-421, 1968.
    • (1968) Arch. Biochem. Biophys. , vol.128 , pp. 406-421
    • Kowal, J.1    Fiedler, R.2
  • 19
    • 0027218455 scopus 로고
    • Regulation of CYP11A gene expression in bovine ovarian granulosa cells in primary culture by cAMP and phorbol esters is conferred by a common cis-acting element
    • Lauber, M. E., H. M. Picton, M. Begeot, K. Momoi, M. R. Waterman, and E. R. Simpson. Regulation of CYP11A gene expression in bovine ovarian granulosa cells in primary culture by cAMP and phorbol esters is conferred by a common cis-acting element. Mol. Cell. Endocrinol. 94: 235-242, 1993.
    • (1993) Mol. Cell. Endocrinol. , vol.94 , pp. 235-242
    • Lauber, M.E.1    Picton, H.M.2    Begeot, M.3    Momoi, K.4    Waterman, M.R.5    Simpson, E.R.6
  • 20
    • 0031003712 scopus 로고    scopus 로고
    • 4 isomerase promoter by the transcription factor steroidogenic factor-1/adrenal 4-binding protein and phorbol ester
    • 4 isomerase promoter by the transcription factor steroidogenic factor-1/adrenal 4-binding protein and phorbol ester. J. Biol. Chem. 272: 7960-7967, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7960-7967
    • Leers-Sucheta, S.1    Morohashi, K.2    Mason, J.I.3    Melner, M.H.4
  • 21
    • 0026606084 scopus 로고
    • Fos and Jun repress transcriptional activation by myogenin and MyoD: The amino terminus of Jun can mediate repression
    • Li, L., J. Chambard, M. Karin, and E. N. Olson. Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression. Genes Dev. 6: 676-689, 1992.
    • (1992) Genes Dev. , vol.6 , pp. 676-689
    • Li, L.1    Chambard, J.2    Karin, M.3    Olson, E.N.4
  • 22
    • 0026537869 scopus 로고
    • Direct effect of arachidonic acid on protein kinase C and LH-stimulated steroidogenesis in rat Leydig cells; evidence for tonic inhibitory control of steroidogenesis by protein kinase C
    • Lopez-Ruiz, M., M. Choi, M. Rose, A. West, and B. Cooke. Direct effect of arachidonic acid on protein kinase C and LH-stimulated steroidogenesis in rat Leydig cells; evidence for tonic inhibitory control of steroidogenesis by protein kinase C. Endocrinology 130:1122-1130, 1992.
    • (1992) Endocrinology , vol.130 , pp. 1122-1130
    • Lopez-Ruiz, M.1    Choi, M.2    Rose, M.3    West, A.4    Cooke, B.5
  • 23
    • 0022911212 scopus 로고
    • The action of phorbol ester on steroidogenesis in cultured human fetal adrenal cells
    • Mason, J., B. Carr, and W. Rainey. The action of phorbol ester on steroidogenesis in cultured human fetal adrenal cells. Endocr. Res. 12:447-467, 1986.
    • (1986) Endocr. Res. , vol.12 , pp. 447-467
    • Mason, J.1    Carr, B.2    Rainey, W.3
  • 24
    • 0023912623 scopus 로고
    • Dual regulation of 3β-hydroxysteroid dehydrogenase, 17α-hydroxylase, and dehydroepiandrosterone sulfotransferase by adenosine 3′,5′-monophosphate and activators of protein kinase C in cultured human adrenocortical cells
    • McAllister, J., and P. Hornsby. Dual regulation of 3β-hydroxysteroid dehydrogenase, 17α-hydroxylase, and dehydroepiandrosterone sulfotransferase by adenosine 3′,5′-monophosphate and activators of protein kinase C in cultured human adrenocortical cells. Endocrinology 122: 2012-2018, 1988.
    • (1988) Endocrinology , vol.122 , pp. 2012-2018
    • McAllister, J.1    Hornsby, P.2
  • 25
    • 0027390601 scopus 로고
    • Fos/jun repression of cardiac-specific transcription in quiescent and growth-stimulated myocytes is targeted at a tissue-specific cis element
    • McBride, K., L. Robitaille, S. Tremblay, S. Argentin, and M. Nemer. Fos/jun repression of cardiac-specific transcription in quiescent and growth-stimulated myocytes is targeted at a tissue-specific cis element. Mol. Cell. Biol. 13: 600-612, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 600-612
    • McBride, K.1    Robitaille, L.2    Tremblay, S.3    Argentin, S.4    Nemer, M.5
  • 26
    • 0024792762 scopus 로고
    • A mutant protein kinase C that can transform fibroblasts
    • Megidish, T., and N. Mazurek. A mutant protein kinase C that can transform fibroblasts. Nature 342:807-811, 1989.
    • (1989) Nature , vol.342 , pp. 807-811
    • Megidish, T.1    Mazurek, N.2
  • 27
    • 0025017957 scopus 로고
    • Human p450scc gene transcription is induced by cyclic AMP and repressed by 12-O-tetradecanolyphorbol-13-acetate and A23187 through independent cis elements
    • Moore, C., S. Brentano, and W. Miller. Human p450scc gene transcription is induced by cyclic AMP and repressed by 12-O-tetradecanolyphorbol-13-acetate and A23187 through independent cis elements. Mol. Cell. Biol. 10: 6013-6023, 1990.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6013-6023
    • Moore, C.1    Brentano, S.2    Miller, W.3
  • 28
    • 9044253707 scopus 로고    scopus 로고
    • Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phophatidylinositol 3-kinase
    • Moriya, S., A. Kazlauskas, K. Akimoo, S. Hirai, K. Mizuno, T. Takenawa, Y. Fukui, Y. Watanabe, S. Ozaki, and S. Ohno. Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phophatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA 93:151-155, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 151-155
    • Moriya, S.1    Kazlauskas, A.2    Akimoo, K.3    Hirai, S.4    Mizuno, K.5    Takenawa, T.6    Fukui, Y.7    Watanabe, Y.8    Ozaki, S.9    Ohno, S.10
  • 29
    • 0029003788 scopus 로고
    • PKCζ is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid
    • Muller, G., M. Ayoub, P. Storz, J. Rennecke, D. Fabbro, and K. Pfizenmaier. PKCζ is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid. EMBO J. 14: 1961-1969, 1995.
    • (1995) EMBO J. , vol.14 , pp. 1961-1969
    • Muller, G.1    Ayoub, M.2    Storz, P.3    Rennecke, J.4    Fabbro, D.5    Pfizenmaier, K.6
  • 30
    • 0025100088 scopus 로고
    • Regulation of 11β- And 17α-hydroxylases in cultured bovine adrenocortical cells: 3′,5′-cyclic adenosine monophosphate, insulin-like growth factor-I, and activators of protein kinase C
    • Naseeruddin, S., and P. Hornsby. Regulation of 11β- and 17α-hydroxylases in cultured bovine adrenocortical cells: 3′,5′-cyclic adenosine monophosphate, insulin-like growth factor-I, and activators of protein kinase C. Endocrinology 127: 1673-1681, 1990.
    • (1990) Endocrinology , vol.127 , pp. 1673-1681
    • Naseeruddin, S.1    Hornsby, P.2
  • 31
    • 0028206862 scopus 로고
    • Role of specific isoforms of protein kinase C in angiotensin II and lipoxygenase action in rat adrenal glomerulosa cells
    • Natarajan, R., L. Lanting, L. Xu, and J. Nadler. Role of specific isoforms of protein kinase C in angiotensin II and lipoxygenase action in rat adrenal glomerulosa cells. Mol. Cell. Endocrinol. 101:59-66, 1994.
    • (1994) Mol. Cell. Endocrinol. , vol.101 , pp. 59-66
    • Natarajan, R.1    Lanting, L.2    Xu, L.3    Nadler, J.4
  • 32
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka, Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334:661-665, 1988.
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 33
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka, Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258: 607-613, 1992.
    • (1992) Science , vol.258 , pp. 607-613
    • Nishizuka, Y.1
  • 34
    • 0024002556 scopus 로고
    • Luciferase reporter gene vectors for analysis of promoters and enhancers
    • Nordeen, S. Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6:454-458, 1988.
    • (1988) Biotechniques , vol.6 , pp. 454-458
    • Nordeen, S.1
  • 35
    • 0025949284 scopus 로고
    • Signal transduction convergence: Phorbol esters and insulin inhibit phosphoenol pyruvate carboxykinase gene transcription through the same 10-base-pair sequence
    • O'Brien, R. M., M. T. Bonovich, C. D. Forest, and D. K. Granner. Signal transduction convergence: phorbol esters and insulin inhibit phosphoenol pyruvate carboxykinase gene transcription through the same 10-base-pair sequence. Proc. Natl. Acad. Sci. USA 88: 6580-6584, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6580-6584
    • O'Brien, R.M.1    Bonovich, M.T.2    Forest, C.D.3    Granner, D.K.4
  • 36
    • 0025259962 scopus 로고
    • Distinctive properties of adrenal cortex mitochondria
    • Orme-Johnson, N. Distinctive properties of adrenal cortex mitochondria. Biochim. Biophys. Acta 1020: 213-231, 1990.
    • (1990) Biochim. Biophys. Acta , vol.1020 , pp. 213-231
    • Orme-Johnson, N.1
  • 37
    • 0027223909 scopus 로고
    • Protein kinase C is a tonic negative regulator of steroidogenesis and steroid hydroxylase gene expression in Y1 adrenal cells and functions independently of protein kinase A
    • Reyland, M. Protein kinase C is a tonic negative regulator of steroidogenesis and steroid hydroxylase gene expression in Y1 adrenal cells and functions independently of protein kinase A. Mol. Endocrinol. 7: 1021-1030, 1993.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1021-1030
    • Reyland, M.1
  • 38
    • 0026030737 scopus 로고
    • Expression of the human apolipoprotein E gene suppresses steroidogenesis in mouse Y1 adrenal cells
    • Reyland, M., J. Gwynne, P. Forgez, M. Prack, and D. Williams. Expression of the human apolipoprotein E gene suppresses steroidogenesis in mouse Y1 adrenal cells. Proc. Natl. Acad. Sci. USA 88: 2375-2379, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2375-2379
    • Reyland, M.1    Gwynne, J.2    Forgez, P.3    Prack, M.4    Williams, D.5
  • 39
    • 0026767481 scopus 로고
    • Increased expression of protein kinase C in Y1 cells which express apolipoprotein E decreases basal steroidogenesis by inhibiting expression of p450-cholesterol side chain cleavage enzyme mRNA
    • Reyland, M., M. Prack, and D. Williams. Increased expression of protein kinase C in Y1 cells which express apolipoprotein E decreases basal steroidogenesis by inhibiting expression of p450-cholesterol side chain cleavage enzyme mRNA. J. Biol. Chem. 267:17935-17942, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17935-17942
    • Reyland, M.1    Prack, M.2    Williams, D.3
  • 40
    • 0025280002 scopus 로고
    • Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme
    • Rice, D., M. Kirkman, L. Aitken, A. Mouw, B. Schimmer, and K. Parker. Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme. J. Biol. Chem. 265:11713-11720, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 11713-11720
    • Rice, D.1    Kirkman, M.2    Aitken, L.3    Mouw, A.4    Schimmer, B.5    Parker, K.6
  • 41
    • 0023868553 scopus 로고
    • Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH
    • Simpson, E. R., and M. R. Waterman. Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. Annu. Rev. Physiol. 50:427-440, 1988.
    • (1988) Annu. Rev. Physiol. , vol.50 , pp. 427-440
    • Simpson, E.R.1    Waterman, M.R.2
  • 42
    • 0021676906 scopus 로고
    • Adrenocortical cytochrome P-450 responsible for cholesterol side chain cleavage (p-450scc) is phosphorylated by the calcium-activated, phospholipid-sensitive protein kinase (protein kinase C)
    • Vilgrain, I., G. Defaye, and E. M. Chambaz. Adrenocortical cytochrome P-450 responsible for cholesterol side chain cleavage (p-450scc) is phosphorylated by the calcium-activated, phospholipid-sensitive protein kinase (protein kinase C). Biochem. Biophys. Res. Commun. 125:554-561, 1984.
    • (1984) Biochem. Biophys. Res. Commun. , vol.125 , pp. 554-561
    • Vilgrain, I.1    Defaye, G.2    Chambaz, E.M.3
  • 43
    • 0022395107 scopus 로고
    • Protein kinase C in adrenal cells: Possible role in regulation of steroid synthesis
    • Widmaier, E., and P. Hall. Protein kinase C in adrenal cells: possible role in regulation of steroid synthesis. Mol. Cell. Endocrinol. 43: 181-188, 1985.
    • (1985) Mol. Cell. Endocrinol. , vol.43 , pp. 181-188
    • Widmaier, E.1    Hall, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.