-
1
-
-
33745617121
-
Confronting the neglected problem of snake bite envenoming: The need for a global partnership
-
Gutiérrez, J. M.; Theakston, R. D.; Warrell, D. A. Confronting the neglected problem of snake bite envenoming: the need for a global partnership. PLoS Med. 2006, 3, e150-159.
-
(2006)
PLoS Med
, vol.3
-
-
Gutiérrez, J.M.1
Theakston, R.D.2
Warrell, D.A.3
-
3
-
-
0032428679
-
Snake-bites: Appraisal of the global situation
-
Chippaux, J. P. Snake-bites: appraisal of the global situation. Bull. World Health Org. 1998, 76, 515-524.
-
(1998)
Bull. World Health Org
, vol.76
, pp. 515-524
-
-
Chippaux, J.P.1
-
4
-
-
56749150556
-
The global burden of snakebite: A literature analysis and modeling based on regional estimates of envenoming and deaths
-
Kasturiratne, A.; Wickremasingue, A. R.; da Silva, N.; Gunawaredna, N. K.; Pathmeswaran, A.; Premaratna, R.; Savioli, L.; Lalloo, D. G.; da Silva, H. J. The global burden of snakebite: a literature analysis and modeling based on regional estimates of envenoming and deaths. PLoS Med. 2008, 5, e218.
-
(2008)
PLoS Med
, vol.5
-
-
Kasturiratne, A.1
Wickremasingue, A.R.2
da Silva, N.3
Gunawaredna, N.K.4
Pathmeswaran, A.5
Premaratna, R.6
Savioli, L.7
Lalloo, D.G.8
da Silva, H.J.9
-
5
-
-
0002852055
-
Clinical toxicology of snakebite in Central America
-
Meier, J, White, J, Eds; CRC Press: Boca Raton, FL
-
Gutiérrez, J. M. Clinical toxicology of snakebite in Central America. In Handbook of Clinical Toxicology of Animal Venoms and Poisons; Meier, J., White, J., Eds; CRC Press: Boca Raton, FL, 1995.
-
(1995)
Handbook of Clinical Toxicology of Animal Venoms and Poisons
-
-
Gutiérrez, J.M.1
-
6
-
-
0002895123
-
Clinical toxicology of snake bites in South America
-
Meier, J, White, J, Eds; CRC Press: Boca Raton, FL
-
Fan, H. W.; Cardoso, J. L. Clinical toxicology of snake bites in South America. In Handbook of Clinical Toxicology of Animal Venoms and Poisons; Meier, J., White, J., Eds; CRC Press: Boca Raton, FL, 1995.
-
(1995)
Handbook of Clinical Toxicology of Animal Venoms and Poisons
-
-
Fan, H.W.1
Cardoso, J.L.2
-
8
-
-
0001130815
-
Las serpientes venenosas de Centroamérica y el problema del ofidismo. Primera parte. Aspectos zoológicos, epidemiológicos y biomédicos.
-
Bolaños, R. Las serpientes venenosas de Centroamérica y el problema del ofidismo. Primera parte. Aspectos zoológicos, epidemiológicos y biomédicos. Rev. Costarricense Cienc. Méd. 1982, 3, 165-184.
-
(1982)
Rev. Costarricense Cienc. Méd
, vol.3
, pp. 165-184
-
-
Bolaños, R.1
-
9
-
-
73649137368
-
Snakebite envenomation in Central America
-
Mackessy, S. P, Ed, CRC Press: Boca Raton, FL
-
Gutiérrez, J. M. Snakebite envenomation in Central America. In Handbook of Venoms and Toxins of Reptiles; Mackessy, S. P., Ed.; CRC Press: Boca Raton, FL, 2009.
-
(2009)
Handbook of Venoms and Toxins of Reptiles
-
-
Gutiérrez, J.M.1
-
10
-
-
0001049038
-
Accidente ofídico en Antioquia y Chocó. Aspectos clínicos y epidemiológicos (marzo de 1989- febrero de 1990).
-
Otero, R.; Tobón, G. S.; Gómez, L. F.; Osorio, R.; Valderrama, R.; Hoyos, D.; Urreta, J. E.; Molina, S.; Arboleda, J. J. Accidente ofídico en Antioquia y Chocó. Aspectos clínicos y epidemiológicos (marzo de 1989- febrero de 1990). Acta Méd. Colomb. 1992, 17, 229-249.
-
(1992)
Acta Méd. Colomb
, vol.17
, pp. 229-249
-
-
Otero, R.1
Tobón, G.S.2
Gómez, L.F.3
Osorio, R.4
Valderrama, R.5
Hoyos, D.6
Urreta, J.E.7
Molina, S.8
Arboleda, J.J.9
-
11
-
-
70149104060
-
Emponzoñamiento of?́dico en el estado Lara
-
Dao, L. Emponzoñamiento of?́dico en el estado Lara. Gaceta Méd. Caracas 1971, 79, 383-410.
-
(1971)
Gaceta Méd. Caracas
, vol.79
, pp. 383-410
-
-
Dao, L.1
-
12
-
-
0030784913
-
Snakebite mortality in Costa Rica
-
Rojas, G.; Bogarín, G.; Gutiérrez, J. M. Snakebite mortality in Costa Rica. Toxicon 1997, 35, 1639-1643.
-
(1997)
Toxicon
, vol.35
, pp. 1639-1643
-
-
Rojas, G.1
Bogarín, G.2
Gutiérrez, J.M.3
-
13
-
-
0001803782
-
Envenenamiento por mordedura de serpiente en Costa Rica: Epidemiología y consideraciones clínicas
-
Arroyo, O.; Rojas, G.; Gutiérrez, J. M. Envenenamiento por mordedura de serpiente en Costa Rica: epidemiología y consideraciones clínicas. Acta Méd. Costarricense 1999, 41, 23-29.
-
(1999)
Acta Méd. Costarricense
, vol.41
, pp. 23-29
-
-
Arroyo, O.1
Rojas, G.2
Gutiérrez, J.M.3
-
14
-
-
0037211969
-
Snakebite envenomation in Costa Rica: A revision of incidence in the decade 1990-2000
-
Sasa, M.; Vázquez, S. Snakebite envenomation in Costa Rica: a revision of incidence in the decade 1990-2000. Toxicon 2003, 41, 19-22.
-
(2003)
Toxicon
, vol.41
, pp. 19-22
-
-
Sasa, M.1
Vázquez, S.2
-
15
-
-
50549085774
-
Mortality due to snakebite envenomation in Costa Rica (1993-2006)
-
Fernández, P.; Gutiérrez, J. M. Mortality due to snakebite envenomation in Costa Rica (1993-2006). Toxicon 2008, 52, 530-533.
-
(2008)
Toxicon
, vol.52
, pp. 530-533
-
-
Fernández, P.1
Gutiérrez, J.M.2
-
16
-
-
73649106786
-
-
Warrell, D. A. Snakebites in Central and South America: Epidemiology, clinical features and clinical management. In The Venomous Reptiles of the Western Hemisphere; Campbell, J. A., Lamar, W. W., Eds; The Venomous Reptiles of the Western Hemisphere. Comstock Publishing Associates: Ithaca, NY, 2004.
-
Warrell, D. A. Snakebites in Central and South America: Epidemiology, clinical features and clinical management. In The Venomous Reptiles of the Western Hemisphere; Campbell, J. A., Lamar, W. W., Eds; The Venomous Reptiles of the Western Hemisphere. Comstock Publishing Associates: Ithaca, NY, 2004.
-
-
-
-
17
-
-
70149120945
-
Epidemiological, clinical and therapeutic aspects of Bothrops asper bites
-
Otero-Patiño, R. Epidemiological, clinical and therapeutic aspects of Bothrops asper bites. Toxicon 2009, 54, 998-1011.
-
(2009)
Toxicon
, vol.54
, pp. 998-1011
-
-
Otero-Patiño, R.1
-
18
-
-
70149112774
-
Experimental pathology of local tissue damage induced by Bothrops asper snake venom
-
Gutiérrez, J. M.; Rucavado, A.; Chaves, F.; Díaz, C.; Escalante, T. Experimental pathology of local tissue damage induced by Bothrops asper snake venom. Toxicon 2009, 54, 958-975.
-
(2009)
Toxicon
, vol.54
, pp. 958-975
-
-
Gutiérrez, J.M.1
Rucavado, A.2
Chaves, F.3
Díaz, C.4
Escalante, T.5
-
19
-
-
70149101319
-
Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom
-
Gutiérrez, J. M.; Escalante, T.; Rucavado, A. Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom. Toxicon 2009, 54, 976-987.
-
(2009)
Toxicon
, vol.54
, pp. 976-987
-
-
Gutiérrez, J.M.1
Escalante, T.2
Rucavado, A.3
-
20
-
-
0035993532
-
-
Otero, R.; Gutiérrez, J.; Mesa, M. B.; Duque, E.; Rodríguez, O.; Arango, J. L.; Gómez, F.; Toro, A.; Cano, F.; Rodríguez, L. M.; Caro, E.; Martínez, J.; Cornejo, W.; Gómez, L. M.; Uribe, F. L.; Cárdenas, S.; Núñez, V.; Díaz, A. Complications of Bothrops, Porthidium, and Bothriechis snakebites in Colombia. A clinical and epidemiological study of 39 cases attended in a university hospital. Toxicon 2002, 40, 1107-1114.
-
Otero, R.; Gutiérrez, J.; Mesa, M. B.; Duque, E.; Rodríguez, O.; Arango, J. L.; Gómez, F.; Toro, A.; Cano, F.; Rodríguez, L. M.; Caro, E.; Martínez, J.; Cornejo, W.; Gómez, L. M.; Uribe, F. L.; Cárdenas, S.; Núñez, V.; Díaz, A. Complications of Bothrops, Porthidium, and Bothriechis snakebites in Colombia. A clinical and epidemiological study of 39 cases attended in a university hospital. Toxicon 2002, 40, 1107-1114.
-
-
-
-
22
-
-
73649116578
-
-
Gutiérrez, J. M.; León, G. Snake antivenoms: Technological, clinical and public health issues. In: Animal Toxins: State of the Art. Perspectives in Health and Biotechnology; de Lima, M. E., Pimenta, A. M. C., Martin-Euclaire, M. F., Zingali, R. B., Rochat, H., Eds.; Editora UFMG: Belo Horizonte, 2009.
-
Gutiérrez, J. M.; León, G. Snake antivenoms: Technological, clinical and public health issues. In: Animal Toxins: State of the Art. Perspectives in Health and Biotechnology; de Lima, M. E., Pimenta, A. M. C., Martin-Euclaire, M. F., Zingali, R. B., Rochat, H., Eds.; Editora UFMG: Belo Horizonte, 2009.
-
-
-
-
23
-
-
67049126873
-
-
Calvete, J. J.; Sanz, L.; Angulo, Y.; Lomonte, B.; Gutiérrez, J. M. Venoms, venomics, antivenomics. FEBS Lett. 2009, 583, 1736-1743.
-
(2009)
FEBS Lett
, vol.583
, pp. 1736-1743
-
-
Calvete, J.J.1
Sanz, L.2
Angulo, Y.3
Lomonte, B.4
Gutiérrez5
Venoms, J.M.6
venomics7
antivenomics8
-
24
-
-
60149098025
-
-
Gutiérrez, J. M.; Lomonte, B.; León, G.; Alape-Girón, A.; Flores-Díaz, M.; Sanz, L.; Angulo, Y.; Calvete, J. J. Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming. J. Proteomics 2009, 72, 165-182.
-
Gutiérrez, J. M.; Lomonte, B.; León, G.; Alape-Girón, A.; Flores-Díaz, M.; Sanz, L.; Angulo, Y.; Calvete, J. J. Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming. J. Proteomics 2009, 72, 165-182.
-
-
-
-
25
-
-
0000340198
-
Venom proteins of the Fer-de-Lance, Bothrops atrox, from Costa Rica
-
Jiménez-Porras, J. M. Venom proteins of the Fer-de-Lance, Bothrops atrox, from Costa Rica. Toxicon 1964, 2, 155-158.
-
(1964)
Toxicon
, vol.2
, pp. 155-158
-
-
Jiménez-Porras, J.M.1
-
26
-
-
0019236371
-
Estudio comparativo de venenos de ejemplares recién nacidos y adultos de Bothrops asper.
-
Gutiérrez, J. M.; Chaves, F.; Bolaños, R. Estudio comparativo de venenos de ejemplares recién nacidos y adultos de Bothrops asper. Rev. Biol. Trop. 1980, 28, 341-351.
-
(1980)
Rev. Biol. Trop
, vol.28
, pp. 341-351
-
-
Gutiérrez, J.M.1
Chaves, F.2
Bolaños, R.3
-
27
-
-
0019767444
-
Bothrops asper from the Atlantic and Pacific zones of Costa Rica
-
Aragón, F.; Gubensek, F. Bothrops asper from the Atlantic and Pacific zones of Costa Rica. Toxicon 1981, 19, 797-805.
-
(1981)
Toxicon
, vol.19
, pp. 797-805
-
-
Aragón, F.1
Gubensek, F.2
-
28
-
-
51649087282
-
Snake venomics of the lancehead pitviper Bothrops asper: Geographic, individual, and ontogenetic variations
-
Alape-Girón, A.; Sanz, L.; Escolano, J.; Flores-Díaz, M.; Madrigal, M.; Sasa, M.; Calvete, J. J. Snake venomics of the lancehead pitviper Bothrops asper: Geographic, individual, and ontogenetic variations. J. Proteome Res. 2008, 7, 3556-3571.
-
(2008)
J. Proteome Res
, vol.7
, pp. 3556-3571
-
-
Alape-Girón, A.1
Sanz, L.2
Escolano, J.3
Flores-Díaz, M.4
Madrigal, M.5
Sasa, M.6
Calvete, J.J.7
-
29
-
-
46449103484
-
Snake venomics and antivenomics of the arboreal neotropical pitvipers Bothriechis lateralis and Bothriechis schlegelii
-
Lomonte, B.; Escolano, J.; Fernández, J.; Sanz, L.; Angulo, Y.; Gutiérrez, J. M.; Calvete, J. J. Snake venomics and antivenomics of the arboreal neotropical pitvipers Bothriechis lateralis and Bothriechis schlegelii. J. Proteome Res. 2008, 7, 2445-2457.
-
(2008)
J. Proteome Res
, vol.7
, pp. 2445-2457
-
-
Lomonte, B.1
Escolano, J.2
Fernández, J.3
Sanz, L.4
Angulo, Y.5
Gutiérrez, J.M.6
Calvete, J.J.7
-
30
-
-
55949105234
-
Snake venomics of the lesser Antillean pit vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with toxicological activities and immunoreactivity of a heterologous antivenom
-
Gutiérrez, J. M.; Sanz, L.; Escolano, J.; Fernández, J.; Lomonte, B.; Angulo, Y.; Rucavado, A.; Warrell, D. A.; Calvete, J. J. Snake venomics of the lesser Antillean pit vipers Bothrops caribbaeus and Bothrops lanceolatus: correlation with toxicological activities and immunoreactivity of a heterologous antivenom. J. Proteome Res. 2008, 7, 4396-4408.
-
(2008)
J. Proteome Res
, vol.7
, pp. 4396-4408
-
-
Gutiérrez, J.M.1
Sanz, L.2
Escolano, J.3
Fernández, J.4
Lomonte, B.5
Angulo, Y.6
Rucavado, A.7
Warrell, D.A.8
Calvete, J.J.9
-
31
-
-
60149089019
-
-
Calvete, J. J.; Borges, A.; Segura, A.; Flores-Díaz, M.; Alape-Girón, A.; Gutiérrez, J. M.; Díez, N.; De Sousa, L.; Kiriakos, D.; Sánchez, E.; Faks, J. G.; Escolano, J.; Sanz, L. Snake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing to its taxonomy and snakebite management. J. Proteomics 2009, 72, 227-240.
-
Calvete, J. J.; Borges, A.; Segura, A.; Flores-Díaz, M.; Alape-Girón, A.; Gutiérrez, J. M.; Díez, N.; De Sousa, L.; Kiriakos, D.; Sánchez, E.; Faks, J. G.; Escolano, J.; Sanz, L. Snake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing to its taxonomy and snakebite management. J. Proteomics 2009, 72, 227-240.
-
-
-
-
32
-
-
0001886294
-
Characterization of venoms and standardization of antivenoms
-
Harris, J. B, Ed, Clarendon Press: Oxford
-
Theakston, R. D. G. Characterization of venoms and standardization of antivenoms. In Natural Toxins. Animal, Plant and Microbial; Harris, J. B., Ed.; Clarendon Press: Oxford, 1986.
-
(1986)
Natural Toxins. Animal, Plant and Microbial
-
-
Theakston, R.D.G.1
-
33
-
-
0000724590
-
Evaluation of the neutralizing ability of antivenoms for the treatment of snake bite envenoming in Central America
-
Bon, C, Goyffon, M, Eds; Fondation Marcel Mérieux: Lyon
-
Gutiérrez, J. M.; Rojas, G.; Bogarín, G.; Lomonte, B. Evaluation of the neutralizing ability of antivenoms for the treatment of snake bite envenoming in Central America. In Envenomings and Their Treatments; Bon, C., Goyffon, M., Eds; Fondation Marcel Mérieux: Lyon, 1996.
-
(1996)
Envenomings and Their Treatments
-
-
Gutiérrez, J.M.1
Rojas, G.2
Bogarín, G.3
Lomonte, B.4
-
35
-
-
0028295746
-
Caprylic acid fractionation of hyperimmune horse plasma: Description of a simple procedure for antivenom production
-
Rojas, G.; Jiménez, J. M.; Gutiérrez, J. M. Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production. Toxicon 1994, 32, 59-67.
-
(1994)
Toxicon
, vol.32
, pp. 59-67
-
-
Rojas, G.1
Jiménez, J.M.2
Gutiérrez, J.M.3
-
36
-
-
0031023402
-
Clinical and laboratory alterations in horses during immunization with snake venoms for the production of polyvalent (Crotalinae) antivenom
-
Angulo, Y.; Estrada, R.; Gutiérrez, J. M. Clinical and laboratory alterations in horses during immunization with snake venoms for the production of polyvalent (Crotalinae) antivenom. Toxicon 1997, 35, 81-90.
-
(1997)
Toxicon
, vol.35
, pp. 81-90
-
-
Angulo, Y.1
Estrada, R.2
Gutiérrez, J.M.3
-
37
-
-
0024999322
-
Epitope mapping of monoclonal antibodies to Escherichia coli ribosomal protein E3
-
Syu, W. J.; Kahan, B.; Kahan, L. Epitope mapping of monoclonal antibodies to Escherichia coli ribosomal protein E3. J. Protein Chem. 1990, 9, 159-167.
-
(1990)
J. Protein Chem
, vol.9
, pp. 159-167
-
-
Syu, W.J.1
Kahan, B.2
Kahan, L.3
-
38
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
39
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin, H.; Staehelin, T.; Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 1979, 76, 4350-4354.
-
(1979)
Proc. Natl. Acad. Sci. U.S.A
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
40
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul, S. F.; Madden, T. L.; Schaffer, A. A.; Zhang, J.; Zhang, Z.; Miller, W.; Lipman, D. J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 1997, 25, 3389-3402.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
41
-
-
0037709383
-
Unique scanning capabilities of a new hybrid linear ion trap mass spectrometer (Q TRAP) used for high sensitivity proteomics applications
-
Le Blanc, J. C.; Hager, J. W.; Ilisiu, A. M.; Hunter, C.; Zhong, F.; Chu, I. Unique scanning capabilities of a new hybrid linear ion trap mass spectrometer (Q TRAP) used for high sensitivity proteomics applications. Proteomics 2003, 3, 859-869.
-
(2003)
Proteomics
, vol.3
, pp. 859-869
-
-
Le Blanc, J.C.1
Hager, J.W.2
Ilisiu, A.M.3
Hunter, C.4
Zhong, F.5
Chu, I.6
-
42
-
-
0348085899
-
-
Universidad de Costa Rica: San José
-
Schosinsky, K.; Vargas, M.; Vinocour, G.; González, O. M.; Brilla, E.; Gutiérrez, A. Manual de Técnicas de Laboratorio. Química Clínica; Universidad de Costa Rica: San José, 1983.
-
(1983)
Manual de Técnicas de Laboratorio. Química Clínica
-
-
Schosinsky, K.1
Vargas, M.2
Vinocour, G.3
González, O.M.4
Brilla, E.5
Gutiérrez, A.6
-
43
-
-
0034029451
-
Neutralization of crotaline snake venoms from Central and South America by antivenoms produced in Brazil and Costa Rica
-
Bogarín, G.; Morais, J. F.; Yamaguchi, I. K.; Stephano, M. A.; Marcelino, J. R.; Nishikawa, A. K.; Guidolin, R.; Rojas, G.; Higashi, H. G.; Gutiérrez, J. M. Neutralization of crotaline snake venoms from Central and South America by antivenoms produced in Brazil and Costa Rica. Toxicon 2000, 38, 1429-1441.
-
(2000)
Toxicon
, vol.38
, pp. 1429-1441
-
-
Bogarín, G.1
Morais, J.F.2
Yamaguchi, I.K.3
Stephano, M.A.4
Marcelino, J.R.5
Nishikawa, A.K.6
Guidolin, R.7
Rojas, G.8
Higashi, H.G.9
Gutiérrez, J.M.10
-
44
-
-
0038696349
-
Preclinical assessment of the ability of polyvalent (Crotalinae) and anticoral (Elapidae) antivenoms produced in Costa Rica to neutralize the venoms of North American snakes
-
Arce, V.; Rojas, E.; Ownby, C. L.; Rojas, G.; Gutiérrez, J. M. Preclinical assessment of the ability of polyvalent (Crotalinae) and anticoral (Elapidae) antivenoms produced in Costa Rica to neutralize the venoms of North American snakes. Toxicon 2003, 41, 851-860.
-
(2003)
Toxicon
, vol.41
, pp. 851-860
-
-
Arce, V.1
Rojas, E.2
Ownby, C.L.3
Rojas, G.4
Gutiérrez, J.M.5
-
45
-
-
10044228408
-
Neutralization of four Peruvian Bothrops sp snake venoms by polyvalent antivenoms produced in Perú and Costa Rica: Preclinical assessment
-
Rojas, E.; Quesada, L.; Arce, V.; Lomonte, B.; Rojas, G.; Gutiérrez, J. M. Neutralization of four Peruvian Bothrops sp snake venoms by polyvalent antivenoms produced in Perú and Costa Rica: preclinical assessment. Acta Tropica 2005, 93, 85-95.
-
(2005)
Acta Tropica
, vol.93
, pp. 85-95
-
-
Rojas, E.1
Quesada, L.2
Arce, V.3
Lomonte, B.4
Rojas, G.5
Gutiérrez, J.M.6
-
46
-
-
0025048405
-
Standardization of assay for testing the neutralizing ability of antivenoms
-
Gutiérrez, J. M.; Rojas, G.; Lomonte, B.; Gené, J. A.; Chaves, F.; Alvarado, J.; Rojas, E. Standardization of assay for testing the neutralizing ability of antivenoms. Toxicon 1990, 28, 1127-1129.
-
(1990)
Toxicon
, vol.28
, pp. 1127-1129
-
-
Gutiérrez, J.M.1
Rojas, G.2
Lomonte, B.3
Gené, J.A.4
Chaves, F.5
Alvarado, J.6
Rojas, E.7
-
47
-
-
0024372242
-
Comparative study on the coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom
-
Gené, J. A.; Roy, A.; Rojas, G.; Gutiérrez, J. M.; Cerdas, L. Comparative study on the coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom. Toxicon 1989, 27, 841-848.
-
(1989)
Toxicon
, vol.27
, pp. 841-848
-
-
Gené, J.A.1
Roy, A.2
Rojas, G.3
Gutiérrez, J.M.4
Cerdas, L.5
-
48
-
-
0022354215
-
Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom
-
Gutiérrez, J. M.; Gené, J. A.; Rojas, G.; Cerdas, L. Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom. Toxicon 1985, 23, 887-893.
-
(1985)
Toxicon
, vol.23
, pp. 887-893
-
-
Gutiérrez, J.M.1
Gené, J.A.2
Rojas, G.3
Cerdas, L.4
-
49
-
-
4744363468
-
A novel P-I class metalloproteinase with broad substrate-cleaving activity, agkislysin, from Agkistrodon acutus venom
-
Wang, W. J.; Shih, C. H.; Huang, T. F. A novel P-I class metalloproteinase with broad substrate-cleaving activity, agkislysin, from Agkistrodon acutus venom. Biochem. Biophys. Res. Commun. 2004, 324, 224-230.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.324
, pp. 224-230
-
-
Wang, W.J.1
Shih, C.H.2
Huang, T.F.3
-
50
-
-
0022467432
-
-
Gutiérrez, J. M.; Lomonte, B.; Chaves, F.; Moreno, E.; Cerdas, L. Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper. Comp. Biochem. Physiol. 1986, 84C, 159-164.
-
Gutiérrez, J. M.; Lomonte, B.; Chaves, F.; Moreno, E.; Cerdas, L. Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper. Comp. Biochem. Physiol. 1986, 84C, 159-164.
-
-
-
-
51
-
-
0037401660
-
Report of a WHO workshop on standardization and control of antivenoms
-
Theakston, R. D. G.; Warrell, D. A.; Griffiths, E. Report of a WHO workshop on standardization and control of antivenoms. Toxicon 2003, 41, 541-557.
-
(2003)
Toxicon
, vol.41
, pp. 541-557
-
-
Theakston, R.D.G.1
Warrell, D.A.2
Griffiths, E.3
-
52
-
-
0026744091
-
Pathological and biochemical changes induced in mice after intramuscular injection of venom from newborn specimens of the snake Bothrops asper (terciopelo)
-
Chaves, F.; Gutiérrez, J. M.; Brenes, F. Pathological and biochemical changes induced in mice after intramuscular injection of venom from newborn specimens of the snake Bothrops asper (terciopelo). Toxicon 1992, 30, 1099-1109.
-
(1992)
Toxicon
, vol.30
, pp. 1099-1109
-
-
Chaves, F.1
Gutiérrez, J.M.2
Brenes, F.3
-
53
-
-
0028924054
-
Isolation and characterization of a metalloproteinase with weak hemorrhagic activity from the venom of the snake Bothrops asper (terciopelo)
-
Gutiérrez, J. M.; Romero, M.; Díaz, C.; Borkow, G.; Ovadia, M. Isolation and characterization of a metalloproteinase with weak hemorrhagic activity from the venom of the snake Bothrops asper (terciopelo). Toxicon 1995, 33, 19-29.
-
(1995)
Toxicon
, vol.33
, pp. 19-29
-
-
Gutiérrez, J.M.1
Romero, M.2
Díaz, C.3
Borkow, G.4
Ovadia, M.5
-
54
-
-
0033991114
-
Purification and characterization of BaH4, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper
-
Franceschi, A.; Rucavado, A.; Mora, N.; Gutiérrez, J. M. Purification and characterization of BaH4, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper. Toxicon 2000, 38, 63-77.
-
(2000)
Toxicon
, vol.38
, pp. 63-77
-
-
Franceschi, A.1
Rucavado, A.2
Mora, N.3
Gutiérrez, J.M.4
-
55
-
-
0027291266
-
Isolation and characterization of synergistic hemorrhagins from the venom of the snake Bothrops asper
-
Borkow, G.; Gutiérrez, J. M.; Ovadia, M. Isolation and characterization of synergistic hemorrhagins from the venom of the snake Bothrops asper. Toxicon 1993, 31, 1137-1150.
-
(1993)
Toxicon
, vol.31
, pp. 1137-1150
-
-
Borkow, G.1
Gutiérrez, J.M.2
Ovadia, M.3
-
56
-
-
0141790425
-
Characterization of 'basparin A', a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis
-
Loría, G. D.; Rucavado, A.; Kamiguti, A. S.; Theakston, R. D. G.; Fox, J.; Alape, A.; Gutiérrez, J. M. Characterization of 'basparin A', a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis. Arch. Biochem. Biophys. 2003, 418, 13-24.
-
(2003)
Arch. Biochem. Biophys
, vol.418
, pp. 13-24
-
-
Loría, G.D.1
Rucavado, A.2
Kamiguti, A.S.3
Theakston, R.D.G.4
Fox, J.5
Alape, A.6
Gutiérrez, J.M.7
-
57
-
-
1642462834
-
Effect of the metalloproteinase inhibitor batimastat in the systemic toxicity induced by Bothrops asper snake venom: Understanding the role of metalloproteinases in envenomation
-
Rucavado, A.; Escalante, T.; Gutiérrez, J. M. Effect of the metalloproteinase inhibitor batimastat in the systemic toxicity induced by Bothrops asper snake venom: understanding the role of metalloproteinases in envenomation. Toxicon 2004, 43, 417-424.
-
(2004)
Toxicon
, vol.43
, pp. 417-424
-
-
Rucavado, A.1
Escalante, T.2
Gutiérrez, J.M.3
-
58
-
-
22144451490
-
Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom. Toxins involved and their contribution to metalloproteinase-induced pulmonary hemorrhage
-
Rucavado, A.; Soto, M.; Escalante, T.; Loría, G. D.; Arni, R. K.; Gutiérrez, J. M. Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom. Toxins involved and their contribution to metalloproteinase-induced pulmonary hemorrhage. Thromb. Haemost. 2005, 94, 123-131.
-
(2005)
Thromb. Haemost
, vol.94
, pp. 123-131
-
-
Rucavado, A.1
Soto, M.2
Escalante, T.3
Loría, G.D.4
Arni, R.K.5
Gutiérrez, J.M.6
-
59
-
-
73649119777
-
Snake venom metalloproteinases. Biological roles and participation in the pathophysiology of envenomation
-
Mackessy, S. P, Ed, CRC Press: Boca Raton, FL
-
Gutiérrez, J. M.; Rucavado, A.; Escalante, T. Snake venom metalloproteinases. Biological roles and participation in the pathophysiology of envenomation. In Handbook of Venoms and Toxins of Reptiles; Mackessy, S. P., Ed.; CRC Press: Boca Raton, FL, 2009.
-
(2009)
Handbook of Venoms and Toxins of Reptiles
-
-
Gutiérrez, J.M.1
Rucavado, A.2
Escalante, T.3
-
60
-
-
0028972997
-
2 myotoxins from Bothrops snake venoms
-
2 myotoxins from Bothrops snake venoms. Toxicon 1995, 33, 1405-1424.
-
(1995)
Toxicon
, vol.33
, pp. 1405-1424
-
-
Gutiérrez, J.M.1
Lomonte, B.2
-
62
-
-
0033731921
-
Snake venom metalloproteinases: Their role in the pathogenesis of local tissue damage
-
Gutiérrez, J. M.; Rucavado, A. Snake venom metalloproteinases: Their role in the pathogenesis of local tissue damage. Biochimie 2000, 82, 841-850.
-
(2000)
Biochimie
, vol.82
, pp. 841-850
-
-
Gutiérrez, J.M.1
Rucavado, A.2
-
63
-
-
0029432140
-
Local tissue damage induced by BaP1, a metalloproteinase isolated fromBothrops asper (terciopelo) snake venom
-
Rucavado, A.; Lomonte, B.; Ovadia, M.; Gutiérrez, J. M. Local tissue damage induced by BaP1, a metalloproteinase isolated fromBothrops asper (terciopelo) snake venom. Exp. Mol. Pathol. 1995, 63, 186-199.
-
(1995)
Exp. Mol. Pathol
, vol.63
, pp. 186-199
-
-
Rucavado, A.1
Lomonte, B.2
Ovadia, M.3
Gutiérrez, J.M.4
-
64
-
-
0031661318
-
-
Rucavado, A.; Núñez, J.; Gutiérrez, J. M. Blister formation and skin damage induced by BaP1, a haemorrhagic metalloproteinase from the venom of the snake Bothrops asper. Int. J. Exp. Pathol. 1998, 79, 245-254.
-
Rucavado, A.; Núñez, J.; Gutiérrez, J. M. Blister formation and skin damage induced by BaP1, a haemorrhagic metalloproteinase from the venom of the snake Bothrops asper. Int. J. Exp. Pathol. 1998, 79, 245-254.
-
-
-
-
65
-
-
51749090417
-
Skin pathology induced by snake venom metalloproteinase: Acute damage, revascularization, and re-epithelization in a mouse model
-
Jiménez, N.; Escalante, T.; Gutiérrez, J. M.; Rucavado, A. Skin pathology induced by snake venom metalloproteinase: Acute damage, revascularization, and re-epithelization in a mouse model. J. Invest. Dermatol. 2008, 128, 2421-2428.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 2421-2428
-
-
Jiménez, N.1
Escalante, T.2
Gutiérrez, J.M.3
Rucavado, A.4
-
66
-
-
1442359906
-
Bothrops asper metalloproteinase BaP1 is inhibited by α2-macroglobulin and mouse serum and does not induce systemic hemorrhage or coagulopathy
-
Escalante, T.; Rucavado, A.; Kamiguti, A. S.; Theakston, R. D. G.; Gutiérrez, J. M. Bothrops asper metalloproteinase BaP1 is inhibited by α2-macroglobulin and mouse serum and does not induce systemic hemorrhage or coagulopathy. Toxicon 2004, 43, 213-217.
-
(2004)
Toxicon
, vol.43
, pp. 213-217
-
-
Escalante, T.1
Rucavado, A.2
Kamiguti, A.S.3
Theakston, R.D.G.4
Gutiérrez, J.M.5
-
67
-
-
57649221923
-
Neutralization of venom-induced hemorrhage by equine antibodies raised by immunization with a plasmid encoding a novel P-II metalloproteinase from the lancehead pitviper Bothrops asper
-
Arce-Estrada, V.; Azofeifa-Cordero, G.; Estrada, R.; Alape-Girón, A.; Flores-Díaz, M. Neutralization of venom-induced hemorrhage by equine antibodies raised by immunization with a plasmid encoding a novel P-II metalloproteinase from the lancehead pitviper Bothrops asper. Vaccine 2009, 27, 460-466.
-
(2009)
Vaccine
, vol.27
, pp. 460-466
-
-
Arce-Estrada, V.1
Azofeifa-Cordero, G.2
Estrada, R.3
Alape-Girón, A.4
Flores-Díaz, M.5
-
68
-
-
0033842555
-
Antibody from mice immunized with DNA encoding the carboxyl-disintegrin and cysteine-rich domain (JD9) of the haemorrhagic metalloprotease, jararhagin, inhibits the main lethal component of viper venom
-
Harrison, R. A.; Moura-da-Silva, A. M.; Laing, G. D.; Wu, Y.; Richards, A.; Broadhead, A.; Bianco, A. E.; Theakston, R. D. G. Antibody from mice immunized with DNA encoding the carboxyl-disintegrin and cysteine-rich domain (JD9) of the haemorrhagic metalloprotease, jararhagin, inhibits the main lethal component of viper venom. Clin. Exp. Immunol. 2000, 121, 358-363.
-
(2000)
Clin. Exp. Immunol
, vol.121
, pp. 358-363
-
-
Harrison, R.A.1
Moura-da-Silva, A.M.2
Laing, G.D.3
Wu, Y.4
Richards, A.5
Broadhead, A.6
Bianco, A.E.7
Theakston, R.D.G.8
-
69
-
-
33745592501
-
Bioinformatics and multiepitope DNA immunization to design rational snake antivenom
-
Wagstaff, S. C.; Laing, G. D.; Theakston, R. D. G.; Papaspyridis, C.; Harrison, R. A. Bioinformatics and multiepitope DNA immunization to design rational snake antivenom. PLoS Med. 2006, 3, e184.
-
(2006)
PLoS Med
, vol.3
-
-
Wagstaff, S.C.1
Laing, G.D.2
Theakston, R.D.G.3
Papaspyridis, C.4
Harrison, R.A.5
-
70
-
-
70350044715
-
-
Núñez, V.; Cid, P.; Sanz, L.; de la Torre, P.; Angulo, Y.; Lomonte, B.; Gutiérrez, J. M.; Calvete, J. J. Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Peru and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism. J. Proteomics 2009, 73, 57-78.
-
Núñez, V.; Cid, P.; Sanz, L.; de la Torre, P.; Angulo, Y.; Lomonte, B.; Gutiérrez, J. M.; Calvete, J. J. Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Peru and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism. J. Proteomics 2009, 73, 57-78.
-
-
-
|