메뉴 건너뛰기




Volumn 37, Issue 1, 2010, Pages 143-149

CRL4Cdt2 E3 Ubiquitin Ligase Monoubiquitinates PCNA to Promote Translesion DNA Synthesis

Author keywords

DNA; PROTEINS

Indexed keywords

CYCLINE; LYSINE; PROTEINASE; RAD18 PROTEIN; UBIQUITIN PROTEIN LIGASE CRL4CDT2; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN SPECIFIC PROTEASE 1; UNCLASSIFIED DRUG;

EID: 73649125005     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.12.018     Document Type: Article
Times cited : (130)

References (28)
  • 1
    • 51949098691 scopus 로고    scopus 로고
    • PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex
    • Abbas T., Sivaprasad U., Terai K., Amador V., Pagano M., and Dutta A. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev. 22 (2008) 2496-2506
    • (2008) Genes Dev. , vol.22 , pp. 2496-2506
    • Abbas, T.1    Sivaprasad, U.2    Terai, K.3    Amador, V.4    Pagano, M.5    Dutta, A.6
  • 2
    • 38049123477 scopus 로고    scopus 로고
    • Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA
    • Andersen P.L., Xu F., and Xiao W. Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA. Cell Res. 18 (2008) 162-173
    • (2008) Cell Res. , vol.18 , pp. 162-173
    • Andersen, P.L.1    Xu, F.2    Xiao, W.3
  • 3
    • 30344455639 scopus 로고    scopus 로고
    • PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication
    • Arias E.E., and Walter J.C. PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication. Nat. Cell Biol. 8 (2006) 84-90
    • (2006) Nat. Cell Biol. , vol.8 , pp. 84-90
    • Arias, E.E.1    Walter, J.C.2
  • 5
    • 48549085044 scopus 로고    scopus 로고
    • The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A
    • Guerrero-Santoro J., Kapetanaki M.G., Hsieh C.L., Gorbachinsky I., Levine A.S., and Rapic-Otrin V. The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A. Cancer Res. 68 (2008) 5014-5022
    • (2008) Cancer Res. , vol.68 , pp. 5014-5022
    • Guerrero-Santoro, J.1    Kapetanaki, M.G.2    Hsieh, C.L.3    Gorbachinsky, I.4    Levine, A.S.5    Rapic-Otrin, V.6
  • 6
    • 33747831132 scopus 로고    scopus 로고
    • L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage
    • Higa L.A., Banks D., Wu M., Kobayashi R., Sun H., and Zhang H. L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage. Cell Cycle 5 (2006) 1675-1680
    • (2006) Cell Cycle , vol.5 , pp. 1675-1680
    • Higa, L.A.1    Banks, D.2    Wu, M.3    Kobayashi, R.4    Sun, H.5    Zhang, H.6
  • 7
    • 0037068455 scopus 로고    scopus 로고
    • RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
    • Hoege C., Pfander B., Moldovan G.L., Pyrowolakis G., and Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419 (2002) 135-141
    • (2002) Nature , vol.419 , pp. 135-141
    • Hoege, C.1    Pfander, B.2    Moldovan, G.L.3    Pyrowolakis, G.4    Jentsch, S.5
  • 9
    • 67349168142 scopus 로고    scopus 로고
    • RAD18 transmits DNA damage signalling to elicit homologous recombination repair
    • Huang J., Huen M.S., Kim H., Leung C.C., Glover J.N., Yu X., and Chen J. RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat. Cell Biol. 11 (2009) 592-603
    • (2009) Nat. Cell Biol. , vol.11 , pp. 592-603
    • Huang, J.1    Huen, M.S.2    Kim, H.3    Leung, C.C.4    Glover, J.N.5    Yu, X.6    Chen, J.7
  • 10
    • 33747873322 scopus 로고    scopus 로고
    • A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1
    • Jin J., Arias E.E., Chen J., Harper J.W., and Walter J.C. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol. Cell 23 (2006) 709-721
    • (2006) Mol. Cell , vol.23 , pp. 709-721
    • Jin, J.1    Arias, E.E.2    Chen, J.3    Harper, J.W.4    Walter, J.C.5
  • 11
    • 2442417331 scopus 로고    scopus 로고
    • Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage
    • Kannouche P.L., Wing J., and Lehmann A.R. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol. Cell 14 (2004) 491-500
    • (2004) Mol. Cell , vol.14 , pp. 491-500
    • Kannouche, P.L.1    Wing, J.2    Lehmann, A.R.3
  • 12
    • 33644536070 scopus 로고    scopus 로고
    • The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites
    • Kapetanaki M.G., Guerrero-Santoro J., Bisi D.C., Hsieh C.L., Rapic-Otrin V., and Levine A.S. The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites. Proc. Natl. Acad. Sci. USA 103 (2006) 2588-2593
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2588-2593
    • Kapetanaki, M.G.1    Guerrero-Santoro, J.2    Bisi, D.C.3    Hsieh, C.L.4    Rapic-Otrin, V.5    Levine, A.S.6
  • 13
    • 57749101303 scopus 로고    scopus 로고
    • Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans
    • Kim S.H., and Michael W.M. Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans. Mol. Cell 32 (2008) 757-766
    • (2008) Mol. Cell , vol.32 , pp. 757-766
    • Kim, S.H.1    Michael, W.M.2
  • 14
    • 51949112601 scopus 로고    scopus 로고
    • The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing
    • Kim Y., Starostina N.G., and Kipreos E.T. The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing. Genes Dev. 22 (2008) 2507-2519
    • (2008) Genes Dev. , vol.22 , pp. 2507-2519
    • Kim, Y.1    Starostina, N.G.2    Kipreos, E.T.3
  • 15
    • 57049133181 scopus 로고    scopus 로고
    • CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation
    • Nishitani H., Shiomi Y., Iida H., Michishita M., Takami T., and Tsurimoto T. CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation. J. Biol. Chem. 283 (2008) 29045-29052
    • (2008) J. Biol. Chem. , vol.283 , pp. 29045-29052
    • Nishitani, H.1    Shiomi, Y.2    Iida, H.3    Michishita, M.4    Takami, T.5    Tsurimoto, T.6
  • 16
    • 33751232623 scopus 로고    scopus 로고
    • Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma
    • Pan H.W., Chou H.Y., Liu S.H., Peng S.Y., Liu C.L., and Hsu H.C. Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma. Cell Cycle 5 (2006) 2676-2687
    • (2006) Cell Cycle , vol.5 , pp. 2676-2687
    • Pan, H.W.1    Chou, H.Y.2    Liu, S.H.3    Peng, S.Y.4    Liu, C.L.5    Hsu, H.C.6
  • 17
    • 0026637161 scopus 로고
    • A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid
    • Parris C.N., and Seidman M.M. A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid. Gene 117 (1992) 1-5
    • (1992) Gene , vol.117 , pp. 1-5
    • Parris, C.N.1    Seidman, M.M.2
  • 19
    • 34247159720 scopus 로고    scopus 로고
    • Overexpression of the human homologue for Caenorhabditis elegans cul-4 gene is associated with poor outcome in node-negative breast cancer
    • Schindl M., Gnant M., Schoppmann S.F., Horvat R., and Birner P. Overexpression of the human homologue for Caenorhabditis elegans cul-4 gene is associated with poor outcome in node-negative breast cancer. Anticancer Res. 27 (2007) 949-952
    • (2007) Anticancer Res. , vol.27 , pp. 949-952
    • Schindl, M.1    Gnant, M.2    Schoppmann, S.F.3    Horvat, R.4    Birner, P.5
  • 20
    • 33646504727 scopus 로고    scopus 로고
    • PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination
    • Senga T., Sivaprasad U., Zhu W., Park J.H., Arias E.E., Walter J.C., and Dutta A. PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination. J. Biol. Chem. 281 (2006) 6246-6252
    • (2006) J. Biol. Chem. , vol.281 , pp. 6246-6252
    • Senga, T.1    Sivaprasad, U.2    Zhu, W.3    Park, J.H.4    Arias, E.E.5    Walter, J.C.6    Dutta, A.7
  • 21
    • 57049097607 scopus 로고    scopus 로고
    • Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase
    • Shibutani S.T., de la Cruz A.F., Tran V., Turbyfill III W.J., Reis T., Edgar B.A., and Duronio R.J. Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase. Dev. Cell 15 (2008) 890-900
    • (2008) Dev. Cell , vol.15 , pp. 890-900
    • Shibutani, S.T.1    de la Cruz, A.F.2    Tran, V.3    Turbyfill III, W.J.4    Reis, T.5    Edgar, B.A.6    Duronio, R.J.7
  • 23
  • 25
    • 33744781568 scopus 로고    scopus 로고
    • Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage
    • Wang H., Zhai L., Xu J., Joo H.Y., Jackson S., Erdjument-Bromage H., Tempst P., Xiong Y., and Zhang Y. Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Mol. Cell 22 (2006) 383-394
    • (2006) Mol. Cell , vol.22 , pp. 383-394
    • Wang, H.1    Zhai, L.2    Xu, J.3    Joo, H.Y.4    Jackson, S.5    Erdjument-Bromage, H.6    Tempst, P.7    Xiong, Y.8    Zhang, Y.9
  • 26
    • 6344288785 scopus 로고    scopus 로고
    • Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination
    • Watanabe K., Tateishi S., Kawasuji M., Tsurimoto T., Inoue H., and Yamaizumi M. Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. EMBO J. 23 (2004) 3886-3896
    • (2004) EMBO J. , vol.23 , pp. 3886-3896
    • Watanabe, K.1    Tateishi, S.2    Kawasuji, M.3    Tsurimoto, T.4    Inoue, H.5    Yamaizumi, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.