Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails

Biochemistry

Volumn 47, Issue 24, 2008, Pages 6403-6417

  Liu, Ying ^a   Wang, Xiqing ^a   Zhang, Jiahai ^a   Huang, Hongda ^a   Ding, Bo ^a   Wu, Jihui ^a   Shi, Yunyu ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BINDING ENERGY; CHROMOSOMES; DYNAMICS; MATHEMATICAL MODELS; MOLECULAR DYNAMICS; MOLECULES; NUCLEAR MAGNETIC RESONANCE; PEPTIDES; PROTEINS; QUANTUM CHEMISTRY; STRUCTURAL PROPERTIES;

(MIN ,MAX ,+) FUNCTIONS; AMERICAN CHEMICAL SOCIETY (ACS); BINDING INTERFACES; BINDING PROPERTIES; BINDING SPECIFICITIES; CELL-CYCLE PROGRESSION; CELLULAR REGULATION; COMPLEX MODELING; HETERODIMERS; INTERNAL MOTIONS; MOLECULAR DYNAMICS SIMULATIONS (MDS); MULTIFUNCTIONAL PROTEINS; MUTATIONAL ANALYSIS; SIGNAL TRANSDUCTION PATHWAYS; SOLUTION STRUCTURES; STRUCTURAL BASIS;

SIGNAL TRANSDUCTION;

BROMODOMAIN 4; HISTONE; MONOMER; PROTEIN;

ACETYLATION; AMINO ACID SEQUENCE; ARTICLE; CHROMATIN; MITOSIS; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

ACETYLATION; AMINO ACID SEQUENCE; CHROMATIN; CRYSTALLOGRAPHY, X-RAY; DNA MUTATIONAL ANALYSIS; HISTONES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MITOSIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

EID: 45749105486     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8001659     Document Type: Article

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