Suppressive effects of phosphorylated ascorbate on ultraviolet B radiation-induced DNA damage and differential expression of the wild-type and mutated p53 tumor-suppressor gene in keratinocytes

Molecular Medicine Reports

Volumn 2, Issue 6, 2009, Pages 917-922

  Sugimoto, Miho ^a   Saitoh, Yasukazu ^a   Ichihashi, Masamitsu ^b   Miwa, Nobuhiko ^a  

^a PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

(6 4)photoproducts; Ascorbic acid 2 O phosphate; p53; Pyrimidine dimer; Ultraviolet

Indexed keywords

ASCORBIC ACID 2 O ALPHA GLUCOSIDE; ASCORBIC ACID 2 SULFATE; ASCORBIC ACID DERIVATIVE; DEHYDROASCORBIC ACID; DNA BASE; PROTEIN MDM2; PROTEIN P53; PYRIMIDINE DIMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER PREVENTION; CANCER RISK; CELL NUCLEUS; CELL PROTECTION; DNA DAMAGE; FIBROBLAST; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; MOUSE; MUTANT; NONHUMAN; ONCOGENE; PROMOTER REGION; PROTEIN FUNCTION; RADIATION CARCINOGENESIS; RADIATION DOSE; RADIATION PROTECTION; RADIATION RESPONSE; SKIN CARCINOGENESIS; SKIN PROTECTION; TUMOR SUPPRESSOR GENE; ULTRAVIOLET B RADIATION; ULTRAVIOLET IRRADIATION; WESTERN BLOTTING; WILD TYPE;

EID: 73649103130     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr_00000192     Document Type: Article

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