Telomere length of the skin in association with chronological aging and photoaging

Journal of Dermatological Science

Volumn 43, Issue 1, 2006, Pages 43-47

  Sugimoto, Miho ^a   Yamashita, Ritsuo ^a   Ueda, Masato ^b  

^a B and C Laboratories Inc   (Japan)

^b Takarazuka Municipal Hospital   (Japan)

Author keywords

Aging; Dermis; Epidermis; Photoaging; Telomere

Indexed keywords

ADULT; AGED; AGING; ARTICLE; CONTROLLED STUDY; DERMIS; EPIDERMIS; HUMAN; HUMAN TISSUE; PHOTOAGING; PRIORITY JOURNAL; SENESCENCE; SKIN; SUN EXPOSURE; TELOMERE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; DERMIS; DNA; EPIDERMIS; HUMANS; MIDDLE AGED; PHENOTYPE; SKIN AGING; TELOMERE;

EID: 33744508373     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2006.02.004     Document Type: Article

References (17)

1. Sharpless N.E., and DePinho R.A. Telomeres, stem cells, senescence, and cancer. J Clin Invest 113 (2004) 160-168
2. Harley C.B., Futcher A.B., and Greider C.W. Telomere shorten during ageing of human fibroblasts. Nature 345 (1990) 458-460
3. von Zglinicki T., Saretzki G., Docke W., and Lotze C. Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence?. Exp Cell Res 220 (1995) 186-193
4. Oikawa S., and Kawanishi S. Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening. FEBS Lett 453 (1999) 365-368
5. Oikawa S., Tada-Oikawa S., and Kawanishi S. Site-specific DNA damage at GGG sequence by UVA involves acceleration of telomere shortening. Biochemistry 40 (2001) 4763-4768
6. Fisher G.J., Kang S., Varani J., Bata-Csorgo Z., Wan Y., Datta S., et al. Mechanisms of photoaging and chronological skin aging. Arch Dermatol 138 (2002) 1462-1470
7. Ueda M., Ouhtit A., Bito T., Nakazawa K., Lubbe J., Ichihashi M., et al. Evidence for UV-associated activation of telomerase in human skin. Cancer Res 57 (1997) 370-374
8. Taylor R.S., Ramirez R.D., Ogoshi M., Chaffins M., Piatyszek M.A., and Shay J.W. Detection of telomerase activity in malignant and nonmalignant skin conditions. J Invest Dermatol 106 (1996) 759-765
9. Lindsey J., McGill N.I., Lindsey L.A., Green D.K., and Cooke H.J. In vivo loss of telomeric repeats with age in humans. Mutat Res 256 (1991) 45-48
10. Friedrich U., Griese E., Schwab M., Fritz P., Thon K., and Klotz U. Telomere length in different tissues of elderly patients. Mech Ageing Dev 119 (2000) 89-99
11. Nakamura K., Izumiyama-Shimomura N., Sawabe M., Arai T., Aoyagi Y., Fujiwara M., et al. Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium. J Invest Dermatol 119 (2002) 1014-1019
12. Frenck Jr. R.W., Blackburn E.H., and Shannon K.M. The rate of telomere sequence loss in human leukocytes varies with age. Proc Natl Acad Sci USA 95 (1998) 5607-5610
13. Kang M.K., Swee J., Kim R.H., Baluda M.A., and Park N.H. The telomeric length and heterogeneity decrease with age in normal human oral keratinocytes. Mech Ageing Dev 123 (2002) 585-592
14. Bickenbach J.R., Vormwald-Dogan V., Bachor C., Bleuel K., Schnapp G., and Boukamp P. Telomerase is not an epidermal stem cell marker and downregulated by calcium. J Invest Dermatol 111 (1998) 1045-1052
15. Ramirez R.D., Wright W.E., Shay J.W., and Taylor R.S. Telomerase activity concentrates in the mitotically active segments of human hair follicles. J Invest Dermatol 108 (1997) 113-117
16. Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., et al. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406 (2000) 641-645
17. Hemann M.T., Strong M.A., Hao L.Y., and Greider C.W. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107 (2001) 67-77