MDM2 Can Promote the Ubiquitination, Nuclear Export, and Degradation of p53 in the Absence of Direct Binding

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 45255-45260

  Inoue, Tomomi ^b   Geyer, Rory K ^b   Howard, David ^b   Yu, Zhong K ^b   Maki, Carl G ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION; DNA; MUTAGENESIS; OLIGOMERS;

NUCLEAR EXPORT;

PROTEINS;

MUTANT PROTEIN; PROTEASOME; PROTEIN MDM2; PROTEIN P53; UBIQUITIN; EPITOPE; ONCOPROTEIN; PROTO ONCOGENE PROTEINS;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; DNA DAMAGE; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; WILD TYPE; ACTIVE TRANSPORT; CELL CULTURE; CELL LINE; CELL NUCLEUS; CYTOPLASM; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; IMMUNOBLOTTING; METABOLISM; MUTATION; PHYSIOLOGY; PLASMID; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS; STRESS; TUMOR SUPPRESSOR GENE;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL LINE; CELL NUCLEUS; CYTOPLASM; DNA DAMAGE; EPITOPES; GENES, P53; HUMAN; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; MUTATION; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN P53; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; STRESS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION; TUMOR CELLS, CULTURED; UBIQUITIN;

EID: 0035977064     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107477200     Document Type: Article

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