-
1
-
-
3843051508
-
Molecular targets for anti-angiogenic therapy
-
Wary KK. Molecular targets for anti-angiogenic therapy. Curr Opin Mol Ther 2004;6:54-70.
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 54-70
-
-
Wary, K.K.1
-
3
-
-
34147174392
-
Endostatin: Current concepts about its biological role and mechanisms of action
-
Digtyar AV, Pozdnyakova NV, Feldman NB, Lutsenko SV, Severin SE. Endostatin: current concepts about its biological role and mechanisms of action. Biochemistry (Mosc) 2007;72:235-46.
-
(2007)
Biochemistry (Mosc)
, vol.72
, pp. 235-246
-
-
Digtyar, A.V.1
Pozdnyakova, N.V.2
Feldman, N.B.3
Lutsenko, S.V.4
Severin, S.E.5
-
4
-
-
0037969161
-
Endostatin action and intracellular signaling: β-catenin as a potential target?
-
Dixelius J, Cross MJ, Matsumoto T, Claesson-Welsh L. Endostatin action and intracellular signaling: β-catenin as a potential target? Cancer Lett 2003;196:1-12.
-
(2003)
Cancer Lett
, vol.196
, pp. 1-12
-
-
Dixelius, J.1
Cross, M.J.2
Matsumoto, T.3
Claesson-Welsh, L.4
-
5
-
-
0034672644
-
Generation and degradation of human endostatin proteins by various proteinases
-
Ferreras M, Felbor U, Lenhard T, Olsen BR, Delaisse J. Generation and degradation of human endostatin proteins by various proteinases. FEBS Lett 2000;486:247-51.
-
(2000)
FEBS Lett
, vol.486
, pp. 247-251
-
-
Ferreras, M.1
Felbor, U.2
Lenhard, T.3
Olsen, B.R.4
Delaisse, J.5
-
6
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly MS, Boehm T, Shing Y, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997;88:277-85.
-
(1997)
Cell
, vol.88
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
-
7
-
-
0025204095
-
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
-
Ingber D, Fujita T, Kishimoto S, et al. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 1990;348:555-7.
-
(1990)
Nature
, vol.348
, pp. 555-557
-
-
Ingber, D.1
Fujita, T.2
Kishimoto, S.3
-
8
-
-
0032529455
-
Suppression of hepatoma growth and angiogenesis by a fumagillin derivative TNP470: Possible involvement of nitric oxide synthase
-
Yoshida T, Kaneko Y, Tsukamoto A, Han K, Ichinose M, Kimura S. Suppression of hepatoma growth and angiogenesis by a fumagillin derivative TNP470: possible involvement of nitric oxide synthase. Cancer Res 1998;58:3751-6.
-
(1998)
Cancer Res
, vol.58
, pp. 3751-3756
-
-
Yoshida, T.1
Kaneko, Y.2
Tsukamoto, A.3
Han, K.4
Ichinose, M.5
Kimura, S.6
-
9
-
-
0034612236
-
Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1
-
Zhang Y, Griffith EC, Sage J, Jacks T, Liu JO. Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1. Proc Natl Acad Sci U S A 2000;97:6427-32.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6427-6432
-
-
Zhang, Y.1
Griffith, E.C.2
Sage, J.3
Jacks, T.4
Liu, J.O.5
-
10
-
-
0033867284
-
Endothelial monocyte-activating polypeptide II, a tumor-derived cytokine that plays an important role in inflammation, apoptosis, and angiogenesis
-
Berger AC, Tang G, Alexander HR, Libutti SK. Endothelial monocyte-activating polypeptide II, a tumor-derived cytokine that plays an important role in inflammation, apoptosis, and angiogenesis. J Immunother 2000;23:519-27.
-
(2000)
J Immunother
, vol.23
, pp. 519-527
-
-
Berger, A.C.1
Tang, G.2
Alexander, H.R.3
Libutti, S.K.4
-
11
-
-
0027959468
-
Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II
-
Kao J, Houck K, Fan Y, et al. Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II. J Biol Chem 1994;269:25106-19.
-
(1994)
J Biol Chem
, vol.269
, pp. 25106-25119
-
-
Kao, J.1
Houck, K.2
Fan, Y.3
-
12
-
-
0026781869
-
Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms
-
Kao J, Ryan J, Brett G, et al. Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms. J Biol Chem 1992;267:20239-47.
-
(1992)
J Biol Chem
, vol.267
, pp. 20239-20247
-
-
Kao, J.1
Ryan, J.2
Brett, G.3
-
13
-
-
0033517112
-
Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells
-
Schwarz MA, Kandel J, Brett J, et al. Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells. J Exp Med 1999;190:341-54.
-
(1999)
J Exp Med
, vol.190
, pp. 341-354
-
-
Schwarz, M.A.1
Kandel, J.2
Brett, J.3
-
14
-
-
0033515887
-
Two distinct cytokines released from a human aminoacyl-tRNA synthetase
-
Wakasugi K, Schimmel P. Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science 1999;284:147-51.
-
(1999)
Science
, vol.284
, pp. 147-151
-
-
Wakasugi, K.1
Schimmel, P.2
-
15
-
-
4444284023
-
Early genetic mechanisms underlying the inhibitory effects of endostatin and fumagillin on human endothelial cells
-
Mazzanti CM, Tandle A, Lorang D, et al. Early genetic mechanisms underlying the inhibitory effects of endostatin and fumagillin on human endothelial cells. Genome Res 2004;14:1585-93.
-
(2004)
Genome Res
, vol.14
, pp. 1585-1593
-
-
Mazzanti, C.M.1
Tandle, A.2
Lorang, D.3
-
16
-
-
20344377898
-
Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells
-
Tandle AT, Mazzanti C, Alexander HR, Roberts DD, Libutti SK. Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells. Cytokine 2005;30:347-58.
-
(2005)
Cytokine
, vol.30
, pp. 347-358
-
-
Tandle, A.T.1
Mazzanti, C.2
Alexander, H.R.3
Roberts, D.D.4
Libutti, S.K.5
-
17
-
-
40749120515
-
Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy
-
Blansfield JA, Caragacianu D, Alexander HR III, et al. Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy. Clin Cancer Res 2008;14:270-80.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 270-280
-
-
Blansfield, J.A.1
Caragacianu, D.2
Alexander III, H.R.3
-
18
-
-
0027754169
-
A morphological biosensor for mammalian cells
-
Giaever I, Keese CR. A morphological biosensor for mammalian cells. Nature 1993;366:591-2.
-
(1993)
Nature
, vol.366
, pp. 591-592
-
-
Giaever, I.1
Keese, C.R.2
-
20
-
-
34347255756
-
Design and construction of targeted AAVP vectors for mammalian cell transduction
-
Hajitou A, Rangel R, Trepel M, et al. Design and construction of targeted AAVP vectors for mammalian cell transduction. Nat Protoc 2007;2:523-31.
-
(2007)
Nat Protoc
, vol.2
, pp. 523-531
-
-
Hajitou, A.1
Rangel, R.2
Trepel, M.3
-
21
-
-
33646034578
-
A hybrid vector for ligand-directed tumor targeting and molecular imaging
-
Hajitou A, Trepel M, Lilley CE, et al. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell 2006;125:385-98.
-
(2006)
Cell
, vol.125
, pp. 385-398
-
-
Hajitou, A.1
Trepel, M.2
Lilley, C.E.3
-
22
-
-
0037177877
-
Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells
-
Schwarze SR, DePrimo SE, Grabert LM, Fu VX, Brooks JD, Jarrard DF. Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells. J Biol Chem 2002;277:14877-83.
-
(2002)
J Biol Chem
, vol.277
, pp. 14877-14883
-
-
Schwarze, S.R.1
DePrimo, S.E.2
Grabert, L.M.3
Fu, V.X.4
Brooks, J.D.5
Jarrard, D.F.6
-
23
-
-
33644876537
-
The identification of senescence-specific genes during the induction of senescence in prostate cancer cells
-
Schwarze SR, Fu VX, Desotelle JA, Kenowski ML, Jarrard DF. The identification of senescence-specific genes during the induction of senescence in prostate cancer cells. Neoplasia 2005;7:816-23.
-
(2005)
Neoplasia
, vol.7
, pp. 816-823
-
-
Schwarze, S.R.1
Fu, V.X.2
Desotelle, J.A.3
Kenowski, M.L.4
Jarrard, D.F.5
-
24
-
-
34347263787
-
Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU
-
Soghomonyan S, Hajitou A, Rangel R, et al. Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU. Nat Protocol 2007;2:416-23.
-
(2007)
Nat Protocol
, vol.2
, pp. 416-423
-
-
Soghomonyan, S.1
Hajitou, A.2
Rangel, R.3
-
25
-
-
33644994202
-
Vascular targeting: Recent advances and therapeutic perspectives
-
Hajitou A, Pasqualini R, Arap W. Vascular targeting: recent advances and therapeutic perspectives. Trends Cardiovasc Med 2006;16:80-8.
-
(2006)
Trends Cardiovasc Med
, vol.16
, pp. 80-88
-
-
Hajitou, A.1
Pasqualini, R.2
Arap, W.3
-
26
-
-
0028031863
-
Molecular cloning of differentially expressed genes in human epithelial ovarian cancer
-
Mok SC, Wong KK, Chan RK, et al. Molecular cloning of differentially expressed genes in human epithelial ovarian cancer. Gynecol Oncol 1994;52:247-52.
-
(1994)
Gynecol Oncol
, vol.52
, pp. 247-252
-
-
Mok, S.C.1
Wong, K.K.2
Chan, R.K.3
-
27
-
-
0036120667
-
Altered patterns of cellular gene expression in dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus
-
Poole LJ, Yu Y, Kim PS, Zheng QZ, Pevsner J, Hayward GS. Altered patterns of cellular gene expression in dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus. J Virol 2002;76:3395-420.
-
(2002)
J Virol
, vol.76
, pp. 3395-3420
-
-
Poole, L.J.1
Yu, Y.2
Kim, P.S.3
Zheng, Q.Z.4
Pevsner, J.5
Hayward, G.S.6
-
28
-
-
32444450151
-
Insights into gene expression changes impacting B-cell transformation: Cross-species microarray analysis of bovine leukemia virus tax-responsive genes in ovine B cells
-
Klener P, Szynal M, Cleuter Y, et al. Insights into gene expression changes impacting B-cell transformation: cross-species microarray analysis of bovine leukemia virus tax-responsive genes in ovine B cells. J Virol 2006;80:1922-38.
-
(2006)
J Virol
, vol.80
, pp. 1922-1938
-
-
Klener, P.1
Szynal, M.2
Cleuter, Y.3
-
29
-
-
0036302046
-
Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone
-
Nagano T, Yoneda T, Hatanaka Y, Kubota C, Murakami F, Sato M. Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone. Nat Cell Biol 2002;4:495-501.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 495-501
-
-
Nagano, T.1
Yoneda, T.2
Hatanaka, Y.3
Kubota, C.4
Murakami, F.5
Sato, M.6
-
30
-
-
7444271413
-
Filamin A and FILIP (Filamin A-Interacting Protein) regulate cell polarity and motility in neocortical subventricular and intermediate zones during radial migration
-
Nagano T, Morikubo S, Sato M. Filamin A and FILIP (Filamin A-Interacting Protein) regulate cell polarity and motility in neocortical subventricular and intermediate zones during radial migration. J Neurosci 2004;24:9648-57.
-
(2004)
J Neurosci
, vol.24
, pp. 9648-9657
-
-
Nagano, T.1
Morikubo, S.2
Sato, M.3
-
31
-
-
0037741121
-
-
Paranavitane V, Coadwell WJ, Eguinoa A, Hawkins PT, Stephens L. LL5h is a phosphatidylinositol (3,4,5)-trisphosphate sensor that can bind the cytoskeletal adaptor, g-filamin. J Biol Chem 2003;278:1328-35.
-
Paranavitane V, Coadwell WJ, Eguinoa A, Hawkins PT, Stephens L. LL5h is a phosphatidylinositol (3,4,5)-trisphosphate sensor that can bind the cytoskeletal adaptor, g-filamin. J Biol Chem 2003;278:1328-35.
-
-
-
-
32
-
-
8744253525
-
A novel partner for Dictyostelium filamin is an a-helical developmentally regulated protein
-
Knuth M, Khaire N, Kuspa A, Lu SJ, Schleicher M, Noegel AA. A novel partner for Dictyostelium filamin is an a-helical developmentally regulated protein. J Cell Sci 2004;117:5013-22.
-
(2004)
J Cell Sci
, vol.117
, pp. 5013-5022
-
-
Knuth, M.1
Khaire, N.2
Kuspa, A.3
Lu, S.J.4
Schleicher, M.5
Noegel, A.A.6
-
34
-
-
0026538371
-
Actin structural proteins in cell motility
-
Cunningham CC. Actin structural proteins in cell motility. Cancer Metastasis Rev 1992;11:69-77.
-
(1992)
Cancer Metastasis Rev
, vol.11
, pp. 69-77
-
-
Cunningham, C.C.1
-
35
-
-
0032422555
-
Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia
-
Fox JW, Lamperti ED, Eksioglu YZ, et al. Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia. Neuron 1998;21:1315-25.
-
(1998)
Neuron
, vol.21
, pp. 1315-1325
-
-
Fox, J.W.1
Lamperti, E.D.2
Eksioglu, Y.Z.3
-
36
-
-
0344522713
-
Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans
-
Robertson SP, Twigg SR, Sutherland-Smith AJ, et al. Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans. Nat Genet 2003;33:487-91.
-
(2003)
Nat Genet
, vol.33
, pp. 487-491
-
-
Robertson, S.P.1
Twigg, S.R.2
Sutherland-Smith, A.J.3
-
37
-
-
0033662155
-
The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin
-
Bellanger JM, Astier C, Sardet C, Ohta Y, Stossel TP, Debant A. The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin. Nat Cell Biol 2000;2:888-92.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 888-892
-
-
Bellanger, J.M.1
Astier, C.2
Sardet, C.3
Ohta, Y.4
Stossel, T.P.5
Debant, A.6
-
38
-
-
0035202874
-
Increased filamin binding to β-integrin cytoplasmic domains inhibits cell migration
-
Calderwood DA, Huttenlocher A, Kiosses WB, et al. Increased filamin binding to β-integrin cytoplasmic domains inhibits cell migration. Nat Cell Biol 2001;3:1060-8.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 1060-1068
-
-
Calderwood, D.A.1
Huttenlocher, A.2
Kiosses, W.B.3
-
39
-
-
34347379258
-
Filamin-A regulates actin-dependent clustering of HIV receptors
-
Jimenez-Baranda S, Gomez-Mouton C, Rojas A, et al. Filamin-A regulates actin-dependent clustering of HIV receptors. Nat Cell Biol 2007;9:838-46.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 838-846
-
-
Jimenez-Baranda, S.1
Gomez-Mouton, C.2
Rojas, A.3
-
40
-
-
0034614656
-
Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2
-
Leonardi A, Ellinger-Ziegelbauer H, Franzoso G, Brown K, Siebenlist U. Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2. J Biol Chem 2000;275:271-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 271-278
-
-
Leonardi, A.1
Ellinger-Ziegelbauer, H.2
Franzoso, G.3
Brown, K.4
Siebenlist, U.5
-
41
-
-
33746658154
-
-
Ohta Y, Hartwig JH, Stossel TP. FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat Cell Biol 2006;8:803-14.
-
Ohta Y, Hartwig JH, Stossel TP. FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat Cell Biol 2006;8:803-14.
-
-
-
-
42
-
-
0035947593
-
Filamin associates with Smads and regulates transforming growth factor-β signaling
-
Sasaki A, Masuda Y, Ohta Y, Ikeda K, Watanabe K. Filamin associates with Smads and regulates transforming growth factor-β signaling. J Biol Chem 2001;276:17871-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 17871-17877
-
-
Sasaki, A.1
Masuda, Y.2
Ohta, Y.3
Ikeda, K.4
Watanabe, K.5
-
43
-
-
0036711657
-
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1
-
Vadlamudi RK, Li F, Adam L, et al. Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1. Nat Cell Biol 2002;4:681-90.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 681-690
-
-
Vadlamudi, R.K.1
Li, F.2
Adam, L.3
-
44
-
-
0036531963
-
Endostatin regulates endothelial cell adhesion and cytoskeletal organization
-
Dixelius J, Cross M, Matsumoto T, Sasaki T, Timpl R, Claesson-Welsh L. Endostatin regulates endothelial cell adhesion and cytoskeletal organization. Cancer Res 2002;62:1944-7.
-
(2002)
Cancer Res
, vol.62
, pp. 1944-1947
-
-
Dixelius, J.1
Cross, M.2
Matsumoto, T.3
Sasaki, T.4
Timpl, R.5
Claesson-Welsh, L.6
-
45
-
-
0141953996
-
Angiogenesis inhibitors target the endothelial cell cytoskeleton through altered regulation of heat shock protein 27 and cofilin
-
Keezer SM, Ivie SE, Krutzsch HC, Tandle A, Libutti SK, Roberts DD. Angiogenesis inhibitors target the endothelial cell cytoskeleton through altered regulation of heat shock protein 27 and cofilin. Cancer Res 2003;63:6405-12.
-
(2003)
Cancer Res
, vol.63
, pp. 6405-6412
-
-
Keezer, S.M.1
Ivie, S.E.2
Krutzsch, H.C.3
Tandle, A.4
Libutti, S.K.5
Roberts, D.D.6
-
46
-
-
0141621070
-
Endostatin associates with lipid rafts and induces reorganization of the actin cytoskeleton via down-regulation of RhoA activity
-
Wickstrom SA, Alitalo K, Keski-Oja J. Endostatin associates with lipid rafts and induces reorganization of the actin cytoskeleton via down-regulation of RhoA activity. J Biol Chem 2003;278:37895-901.
-
(2003)
J Biol Chem
, vol.278
, pp. 37895-37901
-
-
Wickstrom, S.A.1
Alitalo, K.2
Keski-Oja, J.3
-
47
-
-
27744436481
-
Endothelial-monocyte activating polypeptide II alters fibronectin based endothelial cell adhesion and matrix assembly via α5 β1 integrin
-
Schwarz MA, Zheng H, Liu J, Corbett S, Schwarz RE. Endothelial-monocyte activating polypeptide II alters fibronectin based endothelial cell adhesion and matrix assembly via α5 β1 integrin. Exp Cell Res 2005;311:229-39.
-
(2005)
Exp Cell Res
, vol.311
, pp. 229-239
-
-
Schwarz, M.A.1
Zheng, H.2
Liu, J.3
Corbett, S.4
Schwarz, R.E.5
-
48
-
-
33750304277
-
Actin-binding protein filamin A is displayed on the surface of human neuroblastoma cells
-
Bachmann AS, Howard JP, Vogel CW. Actin-binding protein filamin A is displayed on the surface of human neuroblastoma cells. Cancer Sci 2006;97:1359-65.
-
(2006)
Cancer Sci
, vol.97
, pp. 1359-1365
-
-
Bachmann, A.S.1
Howard, J.P.2
Vogel, C.W.3
-
49
-
-
0037077244
-
Cell death and mechanoprotection by filamin a in connective tissues after challenge by applied tensile forces
-
Kainulainen T, Pender A, D'Addario M, Feng Y, Lekic P, McCulloch CA. Cell death and mechanoprotection by filamin a in connective tissues after challenge by applied tensile forces. J Biol Chem 2002;277:21998-2009.
-
(2002)
J Biol Chem
, vol.277
, pp. 21998-22009
-
-
Kainulainen, T.1
Pender, A.2
D'Addario, M.3
Feng, Y.4
Lekic, P.5
McCulloch, C.A.6
-
50
-
-
38949105500
-
Filamin A regulates cell spreading and survival via β1 integrins
-
Kim H, Sengupta A, Glogauer M, McCulloch CA. Filamin A regulates cell spreading and survival via β1 integrins. Exp Cell Res 2008;314:834-46.
-
(2008)
Exp Cell Res
, vol.314
, pp. 834-846
-
-
Kim, H.1
Sengupta, A.2
Glogauer, M.3
McCulloch, C.A.4
|