-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, et al: Global cancer statistics, 2002. CA Cancer J Clin 55:74-108, 2005
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
-
2
-
-
0035863288
-
Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer
-
Yuan A, Yu CJ, Kuo SH, et al: Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer. J Clin Oncol 19:432-441, 2001
-
(2001)
J Clin Oncol
, vol.19
, pp. 432-441
-
-
Yuan, A.1
Yu, C.J.2
Kuo, S.H.3
-
3
-
-
0031045574
-
Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small-cell lung cancer
-
Koukourakis MI, Giatromanolaki A, O'Byrne KJ, et al: Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small-cell lung cancer. Br J Cancer 75:477-481, 1997
-
(1997)
Br J Cancer
, vol.75
, pp. 477-481
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
O'Byrne, K.J.3
-
4
-
-
0034024352
-
Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer
-
O'Byrne KJ, Koukourakis MI, Giatromanolaki A, et al: Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. Br J Cancer 82:1427-1432, 2000
-
(2000)
Br J Cancer
, vol.82
, pp. 1427-1432
-
-
O'Byrne, K.J.1
Koukourakis, M.I.2
Giatromanolaki, A.3
-
5
-
-
23844545810
-
Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas
-
Shikada Y, Yonemitsu Y, Koga T, et al: Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas. Cancer Res 65:7241-7248, 2005
-
(2005)
Cancer Res
, vol.65
, pp. 7241-7248
-
-
Shikada, Y.1
Yonemitsu, Y.2
Koga, T.3
-
6
-
-
0035203484
-
Angiogenesis inhibitors in the treatment of lung cancer
-
suppl 3
-
Shepherd FA: Angiogenesis inhibitors in the treatment of lung cancer. Lung Cancer 34:S81-89, 2001 (suppl 3)
-
(2001)
Lung Cancer
, vol.34
-
-
Shepherd, F.A.1
-
7
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF, et al: Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 22:2184-2191, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
8
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, et al: Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 355:2542-2550, 2006
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
9
-
-
39349094810
-
-
Fehrenbacher L, O'Neil VJ, Belani CP, et al: A phase II, multicenter, randomized clinical trial to evaluate the efficacy and safety of bevacizumab (Avastin) in combination with either chemotherapy (docetaxel or pemetrexed) or erlotinib hydrochloride (Tarceva) compared with chemotherapy alone for treatment of recurrent or refractory non-small cell lung cancer. Slide presentation at the 42nd Annual Meeting of the American Society of Clinical Oncology, June 2-6, Atlanta, GA. Available at http://www.asco.org
-
Fehrenbacher L, O'Neil VJ, Belani CP, et al: A phase II, multicenter, randomized clinical trial to evaluate the efficacy and safety of bevacizumab (Avastin) in combination with either chemotherapy (docetaxel or pemetrexed) or erlotinib hydrochloride (Tarceva) compared with chemotherapy alone for treatment of recurrent or refractory non-small cell lung cancer. Slide presentation at the 42nd Annual Meeting of the American Society of Clinical Oncology, June 2-6, Atlanta, GA. Available at http://www.asco.org
-
-
-
-
10
-
-
78650874372
-
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
-
Abrams TJ, Lee LB, Murray LJ, et al: SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol Cancer Ther 2:471-478, 2003
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 471-478
-
-
Abrams, T.J.1
Lee, L.B.2
Murray, L.J.3
-
11
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, et al: In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 9:327-337, 2003
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
-
12
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell AM, Abrams TJ, Yuen HA, et al: SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 101:3597-3605, 2003
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
-
13
-
-
9144274970
-
SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
-
Murray LJ, Abrams TJ, Long KR, et al: SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 20:757-766, 2003
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 757-766
-
-
Murray, L.J.1
Abrams, T.J.2
Long, K.R.3
-
14
-
-
0141542146
-
PET imaging study of SU11248 in patients with advanced malignancies
-
abstr 767
-
Toner GC, Mitchell PL, De Boer R, et al: PET imaging study of SU11248 in patients with advanced malignancies. Proc Am Soc Clin Oncol 22:191, 2003 (abstr 767)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 191
-
-
Toner, G.C.1
Mitchell, P.L.2
De Boer, R.3
-
15
-
-
33744954585
-
Sunitinib in patients with metastatic renal cell carcinoma
-
Motzer RJ, Rini BI, Bukowski RM, et al: Sunitinib in patients with metastatic renal cell carcinoma. JAMA 295:2516-2524, 2006
-
(2006)
JAMA
, vol.295
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
-
16
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
Motzer RJ, Michaelson MD, Redman BG, et al: Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 24:16-24, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 16-24
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
-
17
-
-
33750844619
-
Updated results from a phase III trial of sunitinib in GIST patients (pts) for whom imatinib (IM) therapy has failed due to resistance or intolerance
-
abstr 9513, 523s
-
Casali PG, Garrett CR, Blackstein ME, et al: Updated results from a phase III trial of sunitinib in GIST patients (pts) for whom imatinib (IM) therapy has failed due to resistance or intolerance. Proc Am Soc Clin Oncol 24:523s, 2006 (abstr 9513)
-
(2006)
Proc Am Soc Clin Oncol
, vol.24
-
-
Casali, P.G.1
Garrett, C.R.2
Blackstein, M.E.3
-
18
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhauer EA, et al: New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205-216, 2000
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
-
19
-
-
0024536437
-
Optimal two-stage designs for phase II clinical trials
-
Simon R: Optimal two-stage designs for phase II clinical trials. Control Clin Trials 10:1-10, 1989
-
(1989)
Control Clin Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
20
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:29-41, 1958
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 29-41
-
-
Kaplan, E.L.1
Meier, P.2
-
21
-
-
0002429117
-
A confidence interval for the median survival time
-
Brookmeyer R, Crowley JJ: A confidence interval for the median survival time. Biometrics 38: 29-41, 1982
-
(1982)
Biometrics
, vol.38
, pp. 29-41
-
-
Brookmeyer, R.1
Crowley, J.J.2
-
22
-
-
33745098620
-
Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase receptor inhibitor SU11248
-
Potapova O, Laird AD, Nannini MA, et al: Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase receptor inhibitor SU11248. Mol Cancer Ther 5:1280-1289, 2006
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1280-1289
-
-
Potapova, O.1
Laird, A.D.2
Nannini, M.A.3
-
23
-
-
0034069620
-
Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
-
Shepherd FA, Dancey J, Ramlau R, et al: Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 18:2095-2103, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 2095-2103
-
-
Shepherd, F.A.1
Dancey, J.2
Ramlau, R.3
-
24
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al: Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 353:123-132, 2005
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
25
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
Hanna N, Shepherd FA, Fossella FV, et al: Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 22:1589-1597, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
-
26
-
-
0034095853
-
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens: The TAX 320 Non-Small Cell Lung Cancer Study Group
-
Fossella FV, DeVore R, Kerr RN, et al: Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens: The TAX 320 Non-Small Cell Lung Cancer Study Group. J Clin Oncol 18:2354-2362, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 2354-2362
-
-
Fossella, F.V.1
DeVore, R.2
Kerr, R.N.3
-
27
-
-
36749052079
-
Efficacy and safety of continuous daily sunitinib dosing in previously treated advanced non-small cell lung cancer (NSCLC): Results from a phase II study
-
suppl
-
Brahmer J, Govindan R, Novello S, et al: Efficacy and safety of continuous daily sunitinib dosing in previously treated advanced non-small cell lung cancer (NSCLC): Results from a phase II study. J Clin Oncol 25:7542, 2007 (suppl)
-
(2007)
J Clin Oncol
, vol.25
, pp. 7542
-
-
Brahmer, J.1
Govindan, R.2
Novello, S.3
-
28
-
-
34548302865
-
Efficacy and safety of sunitinib in a multicenter phase II trial of previously treated, advanced non-small cell lung cancer (NSCLC)
-
suppl 9
-
Socinski MA, Novello S, Sanchez JM, et al: Efficacy and safety of sunitinib in a multicenter phase II trial of previously treated, advanced non-small cell lung cancer (NSCLC). Ann Oncol 17:729PD, 2006 (suppl 9)
-
(2006)
Ann Oncol
, vol.17
-
-
Socinski, M.A.1
Novello, S.2
Sanchez, J.M.3
-
29
-
-
33748913369
-
Phase II trial of single-agent sorafenib in patients with advanced non-small cell lung carcinoma
-
abstr 7002
-
Gatzemeier U, Blumenschein G, Fosella F, et al: Phase II trial of single-agent sorafenib in patients with advanced non-small cell lung carcinoma. Proc Am Soc Clin Oncol 24:18S, 2006 (abstr 7002)
-
(2006)
Proc Am Soc Clin Oncol
, vol.24
-
-
Gatzemeier, U.1
Blumenschein, G.2
Fosella, F.3
|