Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein

Acta Crystallographica Section D: Biological Crystallography

Volumn 65, Issue 11, 2009, Pages 1162-1180

  Lee, Jeffrey E ^a   Fusco, Marnie L ^a   Abelson, Dafna M ^a   Hessell, Ann J ^a   Burton, Dennis R ^a   Saphire, Erica Ollmann ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Antibody complexes; Deglycosylation; Difficult structures; Glycoproteins; Human proteins; Model building; Structure determination; Tactics to improve diffraction; Techniques for phase determination; Viral proteins

Indexed keywords

EBOLA VIRUS; HEXAPODA;

GLYCOPROTEIN; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; EBOLA VIRUS; GENETICS; GLYCOSYLATION; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; CELL LINE; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; EBOLAVIRUS; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; VIRAL ENVELOPE PROTEINS;

EID: 73349143321     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444909032314     Document Type: Article

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