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2 in pivalic acid at 85°C; however, removal of excess pivalic acid is cumbersome.
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2 in pivalic acid at 85°C; however, removal of excess pivalic acid is cumbersome.
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See Supporting Information
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See Supporting Information.
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46
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73349119568
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In favorable cases where the nucleophile is phenol or an unhindered electron-poor substituted phenol, the transformation can undoubtedly be carried out in satisfactory fashion using lower catalyst loadings
-
In favorable cases where the nucleophile is phenol or an unhindered electron-poor substituted phenol, the transformation can undoubtedly be carried out in satisfactory fashion using lower catalyst loadings.
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47
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73349133214
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2 are available from Aldrich Chemical Co.
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2 are available from Aldrich Chemical Co.
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48
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73249153734
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The origin of these differences is not yet fully understood. We note that an external anionic ligand has been shown to be coordinated to palladium during the ratedetermining step of the rearrangement of allylic trichloroacetimidates catalyzed by [COP-Cl2, 8a] whereas both the double bond and the imidate nitrogen have been proposed to be bound to palladium during the reaction of allylic trichloroacetimidates with carboxylate nucleophiles.[7
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[7]
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