Efficient siRNA delivery to mammalian cells using layered double hydroxide nanoparticles

Biomaterials

Volumn 31, Issue 7, 2010, Pages 1821-1829

  Ladewig, Katharina ^a   Niebert, Marcus ^b   Xu, Zhi P ^a   Gray, Peter P ^a   Lu, Gao Q M ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Layered double hydroxide nanoparticles; siRNA delivery

Indexed keywords

CELL VIABILITY; CLINICAL APPLICATION; DELIVERY SYSTEMS; DOWN-REGULATION; ENDOSOMES; IN-VITRO; IN-VIVO; INORGANIC CRYSTALS; INORGANIC NANOPARTICLE; LAYERED DOUBLE HYDROXIDE NANOPARTICLES; LAYERED DOUBLE HYDROXIDES; LDH NANOPARTICLE; MAMMALIAN CELLS; PROTEIN EXPRESSIONS; SIRNA DELIVERY;

CYTOLOGY; GENE EXPRESSION; MAMMALS; NUCLEIC ACIDS; RNA;

NANOPARTICLES;

HYDROXIDE; NANOPARTICLE; SMALL INTERFERING RNA;

ARTICLE; BINDING KINETICS; CELL PROLIFERATION; CELL STRAIN HEK293; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL; CYTOPLASM; DISSOLUTION; DOWN REGULATION; EMBRYO; ENDOCYTOSIS; ENDOSOME; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAMMAL CELL; NONVIRAL GENE DELIVERY SYSTEM; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE;

CELL DEATH; CELL LINE; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; GENE KNOCKDOWN TECHNIQUES; GENE TRANSFER TECHNIQUES; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROXIDES; NANOPARTICLES; OLIGONUCLEOTIDES; PARTICLE SIZE; RNA, SMALL INTERFERING; TRANSFECTION;

MAMMALIA;

EID: 73249144464     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.10.058     Document Type: Article

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