Engineering rice based medium for production of lovastatin with Monascus species

Czech Journal of Food Sciences

Volumn 27, Issue 5, 2009, Pages 352-360

  Panda, Bibhu Prasad ^a   Javed, Saleem ^a   Ali, Mohamed ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Angkak; Lovastatin; Medium engineering; Monascus sp.

Indexed keywords

MONASCUS; MONASCUS PURPUREUS;

EID: 73249117086     PISSN: 12121800     EISSN: None     Source Type: Journal    
DOI: 10.17221/47/2008-cjfs     Document Type: Article

References (28)

1. ABDEL-FATTAH Y. R., ENSHASY H. E., ANWAR M., OMAR H., ABOLMAGD E., ZAHRA R. A. (2007): Application of factorial experimental designs for optimization of cyclosporin a production by Tolypocladium inflatum in submerged culture. Journal of Microbiology and Biotechnology, 12:1930-1936.
2. BOX G. E. P., HUNTER J. S. (1957): Multifactor experimental design for exploring response surfaces. The Annals of Mathematical Statistics, 28:195-241.
3. CHAKRAVARTI R., SAHAI V. (2002): Optimization of compactin production in chemically defined production medium by Penicillium citrinum using statistical methods. Process Biochemistry, 38:481-486.
4. CHANG Y. C., LEE C. L., PAN T. M. (2006): Statistical optimization of medium components for the production of Antrodia cinnamomea AC0623 in submerged cultures. Applied Microbiology and Biotechnology, 72:654-661.
5. CHANG Y. N., HUANG J. C., LEE C. C., SHIH I. L., TZENG Y. M. (2002): Use of response surface methodology to optimize production of lovastatin by Monascus ruber. Enzyme and Microbial Technology, 30:889-894.
6. CHAUHAN K., TRIVEDI U., PATEL K. C. (2006): Application of response surface methodology for optimization of lactic acid production using date juice. Journal of Microbiology and Biotechnology, 9:1410-1415.
7. CHEN F., HU X. (2005): Study on red fermented rice with high concentration of monacolin K and low concentration of citrinin. International Journal of Food Microbiology, 103:331-337.
8. CHIU C. H., NI K. H., GUU Y. K., PAN T. M. (2006): Production of red mold rice using a modified Nagata type koji marker. Applied Microbiology and Biotechnology, 73:297-304.
9. ENDO A. (1979): Monacolin K, a new hypocholesterolemic agent produced by a Monascus species. Journal of Antibiotics, 32:852-854.
10. ENDO A. (1980): Monacolin K, a new hypocholesterolemic agent that specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme a reductase. Journal of Antibiotics, 33:334-336.
11. HAJJAJ H., KLAEBE A., GOMA G., BLANC P. J., BARBIER E., FRANCOIS J. (2000): Medium-chain fatty acids affect citrinin production in the filamentous fungus Monascus ruber. Applied and Environmental Microbiology, 66:1120-1125.
12. KENNEDY M., KROUSE D. (1999): Strategies for improving fermentation medium performance: a review. Journal of Industrial Microbiology and Biotechnology, 23:456-475.
13. KOHAMA Y., MATSUMOTO S., MIMURA T., TANABE N., INADA A., NAKANISHI T. (1987): Isolation and identification of hypotensive principles in red-mold rice. Chemical & Pharmaceutical Bulletin, 35:2484-2489.
14. LEE C. L., WANG J. J., KUO S. L., PAN T. M. (2006a): Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agents - monacolin K and antiinflamation agent - monascin. Applied Microbiology and Biotechnology, 72:1254-1262.
15. LEE C. L., TSAI T. Y., WANG J. J., PAN T. M. (2006b): In vivo hypolipidemic effects and safety of low dosage Monascus powder in hamster model of hyperlipidemia. Applied Microbiology and Biotechnology, 70:533-540.
16. LIN Y. L., WANG T. H., LEE M. H., SU N. W. (2008): Biologically active components and nutraceuticals in the Monascus-fermented rice: a review. Applied Microbiology and Biotechnology, 77:965-973.
17. MIYAKE T., MORI A., KII T., OKUNO T., USUI Y., FUMIHIRO S., SAMMOTO H., WATANABE A., KARIYAMA M. (2005): Light effects on cell development and secondary metabolism in Monascus. Journal of Industrial Microbiology and Biotechnology, 32:103-108.
18. MIYAKE T., UCHITOMO K., ZHANG M. Y., KONO I., NOZAKI N., SAMMOTO H., INAGAKI K. (2006): Effects of the principle nutrients on lovastatin production by Monascus pilosus. Bioscience Biotechnology & Biochemistry, 70:1154-1159.
19. NAVEENA B. J., ALTAF M., BHADRIAH K., REDDY G. (2005): Selection of medium components by Plackett-Burman design for production of L (+) lactic acid by Lactobacillus amylophilus GV6 in SSF using wheat bran. Bioresource Technology, 96:485-490.
20. PANDA B. P., JAVED S., ALI M. (2007): Fermentation process optimization. Research Journal of Microbiology, 2:201-208.
21. PLACKETT R. L., BURMAN J. P. (1946): The design of optimum multi factorial experiments. Biometrika, 33:305-325.
22. POPA O., BABEANU N., VAMANU A., VAMANU E. (2007): The utilization of the response surface methodology for the optimization of cultivation medium and growth parameters in the cultivation of the yeast strain S. cerevisiae 3.20 on ethanol. African Journal of Biotechnology, 23:2700-2707.
23. SAMIEE S. M., MOAZAMI N., HAGHIGHI S., MOHSEN F. A., MIRDAMADI S., BAKHTIARI M. R. (2003): Screening of lovastatin production by filamentous fungi. Iranian Biomedical Journal, 7:29-33.
24. SAYYAD S. A., PANDA B. P., JAVED S., ALI M. (2007a): Optimization of nutrient parameters for lovastatin production by Monascus purpureus MTCC 369 under submerged fermentation using response surface methodology. Applied Microbiology and Biotechnology, 73:1054-1058.
25. SAYYAD S. A., PANDA B. P., JAVED S., ALI M. (2007b): Screening of nutrient parameters for lovastatin production by Monascus purpureus MTCC 369 under submerged fermentation using Plackett-Burman design. Research Journal of Microbiology, 2:601-605.
26. SU N. W., LIN Y. L., LEE M. H., HO C. Y. (2005): Ankaflavin from Monascus fermented red rice exhibits selective cytotoxic effect and induces cell death on Hep G2 cells. Journal of Agricultural and Food Chemistry, 53:1949-1954.
27. SU Y. C., WANG J. J., LIN T. T., PAN T. M. (2003): Production of secondary metabolites, γ-amino butyric acid and monacolin K by Monascus. Journal of Industrial Microbiology and Biotechnology, 30:41-46.
28. TAIRA J., MIYAGI C., ANIYA Y. (2002): Dimerumic acid as an antioxidant from the mold, Monascus anka: the inhibition mechanisms against lipid peroxidation and hemeprotein-mediated oxidation. Biochemical Pharmacology, 63:1019-1026. YU X., HALLETT S. G., SHEPPARD J., WATSON A. K. (1997): Application of Plackett-Burman experimental design to evaluate nutritional requirements for the production of Collectotrichum coccodes spores. Applied Microbiology and Biotechnology, 47:301-305.