Optimization of compactin production in chemically defined production medium by Penicillium citrinum using statistical methods

Process Biochemistry

Volumn 38, Issue 4, 2002, Pages 481-486

  Chakravarti, R ^a   Sahai, V ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

Author keywords

Central composite rotatable design; Compactin; Penicillium citrinum; Plackett Burman design; Regression coefficients; Response surface plots

Indexed keywords

PENICILLIUM; PENICILLIUM CITRINUM;

EID: 0037010802     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0032-9592(02)00138-3     Document Type: Article

References (20)

1. Endo A. Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase. J Med Chem 1985;28:1401-25.
2. Ballantyne CM. Current thinking in lipid lowering. Am J Med 1998;104(Suppl. 1):33S-41S.
3. Water DD. Are we aggressive enough in lowering cholesterol. Am J Cardiol 2001;88(Suppl):10F-5F.
4. Plackett RL, Burman JP. The design of optimum multifactorial experiments. Biometrika 1946;33:305-25.
5. Box GEP, Wilson KB. On the experimental attainment of optimum conditions. J R Stat Soc B 1951;13(series B):1-45.
6. Box GEP, Hunter JS. Multifactor experimental design for exploring response surfaces. Annu Math Star 1957;28:195-241.
7. Khuri AL, Cornell JA. Determining optimum conditions. In: Khuri AI, Cornell JA, editors. Response Surface-design and Analyses. New York: Marcel Dekker, 1987.
8. Narang S, Sahai V, Bisaria VS. Optimzation of xylanase production by Melanocarpus albomyces IIS68 in solid state fermentation using the response surface methodology. J Biosci Bioeng 2001;91:425-7.
9. Dey G, Mitra A, Banerjee R, Maiti BR. Enhanced production of amylase by optimization of nutritional constituents using response surface methodology. Biochem Eng J 2001;7:227-31.
10. Harris PL, Cuppett SL, Bullerman LB. Otimization of lipase synthesis by Pseudomonas fluorescence by response surface methodology. J Food Protect 1990;53:481-3.
11. Rodrigues MI, Maciel-Filho R, Maugeri F. Optimization of a process of continuous enzyme purification by surface response analysis. Food Control 1993;4:144-8.
12. Bazaraa WA, Hassan EE. Response surface optimisation for the continuous glucose isomerization process. J Ind Microbiol 1996;17:100-3.
13. Rao KJ, Kim CH, Rhee SK. Statistical optimization of medium for the production of recombinant hirudin from Saccharomyces cerevisiae using response surface methodology. Process Biochem 2000;35:639-47.
14. Kiran KR, Manohar B, Divakar S. A central composite rotatable design analysis of lipase catalyzed synthesis of lauroyl lactic acid at bench scale level. Enzyme Microb Technol 2001;29:122-8.
15. Bowmen L, Geiger E. Optimization of fermentation conditions for alcohol production. Biotechnol Bioeng 1984;26:1492-7.
16. Kalil SJ, Maugeri F, Rodrigues MI. Response surface analysis and simulation as a tool for bioprocess design and optimization. Process Biochem 2000;35:539-50.
17. Roseiro JC, Esgalhado ME, Amaral Collaco MT, Emery AN. Medium development for xanthan production. Process Biochem 1992;27:167-75.
18. Prapulla SG, Jacob Z, Chand N, Rajalakshmi D, Karanth NG. Maximization of lipid production by Rhodoterula gracilis CFR-1 using the response surface methodology. Biotechnol Bioeng 1992;40:965-70.
19. Konya A, Jekkel A, Suto J, Salat J. Optimization of compactin fermentation. J Ind Microbiol Biotechnol 1998;20:150-2.
20. Auerbach C. Mutagenesis by ultraviolet and visible light II and III. In: Auerbach C, editor. Mutation Research, Problems, Results and Perspective. London: Chapman and Hall, 1976:173-217.