Impact on the corneal endothelium of mitomycin C during photorefractive keratectomy

Journal of Refractive Surgery

Volumn 25, Issue 10, 2009, Pages 894-897

  Roh, Danny S ^a   Funderburgh, James L ^a  

^a University of Pittsburgh School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C;

CELL DENSITY; CELL LOSS; CORNEA ENDOTHELIUM; DNA CROSS LINKING; DNA REPAIR; DRUG ACTIVATION; ENDOTHELIUM CELL; NONHUMAN; PHOTOREFRACTIVE KERATECTOMY; PRIORITY JOURNAL; REDUCTION; SHORT SURVEY;

ALKYLATING AGENTS; ANIMALS; CELL COUNT; ENDOTHELIUM, CORNEAL; HUMANS; LASERS, EXCIMER; MITOMYCIN; PHOTOREFRACTIVE KERATECTOMY;

EID: 73149110838     PISSN: 1081597X     EISSN: None     Source Type: Journal    
DOI: 10.3928/1081597X-20090617-10     Document Type: Short Survey

References (28)

1. Talamo JH, Gollamudi S, Green WR, De La Cruz Z, Filatov V, Stark WJ. Modulation of corneal wound healing after excimer laser keratomileusis using topical mitomycin C and steroids. Arch Ophthalmol. 1991;109:1141-1146.
2. Lacayo GO III, Majmudar PA. How and when to use mitomycin-C in refractive surgery. Curr Opin Ophthalmol. 2005;16:256-259.
3. Tomasz M. Mitomycin C: small, fast and deadly (but very selective). Chem Biol. 1995;2:575-579.
4. Schelonka LP, Siegel D, Wilson MW, Meininger A, Ross D. Immunohistochemical localization of NQO1 in epithelial dysplasia and neoplasia and in donor eyes. Invest Ophthalmol Vis Sci. 2000;41:1617-1622.
5. McHugh PJ, Spanswick VJ, Hartley JA. Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance. Lancet Oncol. 2001;2:483-490.
6. Noll DM, Mason TM, Miller PS. Formation and repair of interstrand cross-links in DNA. Chem Rev. 2006;106:277-301.
7. Dronkert ML, Kanaar R. Repair of DNA interstrand cross-links. Mutat Res. 2001;486:217-247.
8. De Silva IU, McHugh PJ, Clingen PH, Hartley JA. Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol. 2000;20:7980-7990.
9. Niedernhofer LJ, Odijk H, Budzowska M, van Drunen E, Maas A, Theil AF, de Wit J, Jaspers NG, Beverloo HB, Hoeijmakers JH, Kanaar R. The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks. Mol Cell Biol. 2004;24:5776-5787.
10. Abbas T, Olivier M, Lopez J, Houser S, Xiao G, Kumar GS, Tomasz M, Bargonetti J. Differential activation of p53 by the various adducts of mitomycin C. J Biol Chem. 2002;277:40513-40519.
11. Boamah EK, White DE, Talbott KE, Arva NC, Berman D, Tomasz M, Bargonetti J. Mitomycin-DNA adducts induce p53-dependent and p53-independent cell death pathways. ACS Chem Biol. 2007;2:399-407.
12. Grillari J, Katinger H, Voglauer R. Contributions of DNA interstrand cross-links to aging of cells and organisms. Nucleic Acids Res. 2007;35:7566-7576.
13. Torres RM, Merayo-Lloves J, Daya SM, Blanco-Mezquita JT, Espinosa M, Nozal MJ, Bernal JL, Bernal J. Presence of mitomycin-C in the anterior chamber after photorefractive keratectomy. J Cataract Refract Surg. 2006;32:67-71.
14. Song JS, Kim JH, Yang M, Sul D, Kim HM. Concentrations of mitomycin C in rabbit corneal tissue and aqueous humor after topical administration. Cornea. 2006;25:S20-S23.
15. Roh DS, Cook AL, Rhee SS, Joshi A, Kowalski R, Dhaliwal DK, Funderburgh JL. DNA cross-linking, double-strand breaks and apoptosis in corneal endothelial cells after a single exposure to mitomycin-C. Invest Ophthalmol Vis Sci. 2008;49:4837-4843.
16. McDermott ML, Wang J, Shin DH. Mitomycin and the human corneal endothelium. Arch Ophthalmol. 1994;112:533-537.
17. Garweg JG, Wegmann-Burns M, Goldblum D. Effects of daunorubicin, mitomycin C, azathioprine and cyclosporin A on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines. Graefes Arch Clin Exp Ophthalmol. 2006;244:382-389.
18. Wu KY, Hong SJ, Huang HT, Lin CP, Chen CW. Toxic effects of mitomycin-C on cultured corneal keratocytes and endothelial cells. J Ocul Pharmacol Ther. 1999;15:401-411.
19. Chang SW. Early corneal edema following topical application of mitomycin-C. J Cataract Refract Surg. 2004;30:1742-1750.
20. Lee DH, Chung HS, Jeon YC, Boo SD, Yoon YD, Kim JG. Photorefractive keratectomy with intraoperative mitomycin-C application. J Cataract Refract Surg. 2005;31:2293-2298.
21. Goldsberry DH, Epstein RJ, Majmudar PA, Epstein RH, Dennis RF, Holley G, Edelhauser HF. Effect of mitomycin C on the corneal endothelium when used for corneal subepithelial haze prophylaxis following photorefractive keratectomy. J Refract Surg. 2007;23:724-727.
22. Diakonis VF, Pallikaris A, Kymionis GD, Markomanolakis MM. Alterations in endothelial cell density after photorefractive keratectomy with adjuvant mitomycin. Am J Ophthalmol. 2007;144:99-103.
23. Nassiri N, Farahangiz S, Rahnavardi M, Rahmani L. Corneal endothelial cell injury induced by mitomycin-C in photorefractive keratectomy: nonrandomized controlled trial. J Cataract Refract Surg. 2008;34:902-908.
24. Morales AJ, Zadok D, Mora-Retana R, Martínez-Gama E, Robledo NE, Chayet AS. Intraoperative mitomycin and corneal endothelium after photorefractive keratectomy. Am J Ophthalmol. 2006;142:400-404.
25. Avisar R, Avisar I, Bahar I, Weinberger D. Effect of mitomycin C in pterygium surgery on corneal endothelium. Cornea. 2008;27:559-561.
26. Mohammadpour M, Jabbarvand M, Javadi MA. Focal corneal decompensation after filtering surgery with mitomycin C. Cornea. 2007;26:1285-1287.
27. Mietz H, Roters S, Krieglstein GK. Bullous keratopathy as a complication of trabeculectomy with mitomycin C. Graefes Arch Clin Exp Ophthalmol. 2005;243:1284-1287.
28. Pfister RR. Permanent corneal edema resulting from the treatment of PTK corneal haze with mitomycin: a case report. Cornea. 2004;23:744-747.