Effect of mitomycin C on the corneal endothelium when used for corneal subepithelial haze prophylaxis following photorefractive keratectomy

Journal of Refractive Surgery

Volumn 23, Issue 7, 2007, Pages 724-727

  Goldsberry, Dennis H ^a   Epstein, Randy J ^a,d   Majmudar, Parag A ^a   Epstein, Rachel H ^b   Dennis, Richard F ^a   Holley, Glenn ^c   Edelhauser, Henry F ^c  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C;

ARTICLE; CELL DENSITY; CLINICAL ARTICLE; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORRELATION COEFFICIENT; DRUG EFFECT; DRUG EFFICACY; ENDOTHELIUM CELL; FOLLOW UP; HUMAN; MYOPIA; PHOTOREFRACTIVE KERATECTOMY; PRIORITY JOURNAL; SPECULAR MICROSCOPY; STATISTICAL ANALYSIS;

EID: 34548718295     PISSN: 1081597X     EISSN: None     Source Type: Journal    
DOI: 10.3928/1081-597x-20070901-14     Document Type: Article

References (20)

1. Talamo JH, Gollamudi S, Green WR, De La Cruz Z, Filatov V, Stark WJ. Modulation of corneal wound healing after excimer laser keratomileusis using topical mitomycin C and steroids. Arch Ophthalmol. 1991;109:1141-1146.
2. Majmudar PA, Forstot SL, Dennis RF, Nirankari VS, Damiano RE, Brenart R, Epstein RJ. Topical mitomycin-C for subepithelial fibrosis after refractive corneal surgery. Ophthalmology. 2000;107:89-94.
3. Raviv T, Majmudar PA, Dennis RF, Epstein RJ. Mitomycin-C for post-PRK corneal haze. J Cataract Refract Surg. 2000;26:1105-1106.
4. Kim TI, Tchah H, Lee SA, Sung K, Cho BJ, Kook MS. Apoptosis in keratocytes caused by mitomycin C. Invest Ophthalmol Vis Sci. 2003;44:1912-1917.
5. Manche EE, Afshari MA, Singh K. Delayed corneal epitheliopathy after antimetabolite-augmented trabeculectomy. J Glaucoma. 1998;7:237-239.
6. McDermott ML, Wang J, Shin DH. Mitomycin and the human corneal endothelium. Arch Ophthalmol. 1994;112:533-537.
7. Sadeghi HM, Seitz B, Hayashi S, LaBree L, McDonnell PJ. In vitro effects of mitomycin-C on human keratocytes. J Refract Surg. 1998;14:534-540.
8. Wu KY, Hong SJ, Huang HT, Lin CP, Chen CW. Toxic effects of mitomycin-C on cultured corneal keratocytes and endothelial cells. J Ocul Pharmacol Ther. 1999;15:401-411.
9. Nuyts RM, Pels E, Greve EL. The effects of 5-fluorouracil and mitomycin C on the corneal endothelium. Curr Eye Res. 1992;11:565-570.
10. Schultz RO, Matsuda M, Yee RW, Edelhauser HF, Schultz KJ. Corneal endothelial changes in type I and type II diabetes mellitus. Am J Ophthalmol. 1984;98:401-410.
11. Geroski DH, Edelhauser HF. Morphometric analysis of the corneal endothelium. Specular microscopy vs. alizarin red staining. Invest Ophthalmol Vis Sci. 1989;30:254-259.
12. Caubet E. Course of subepithelial corneal haze over 18 months after photorefractive keratectomy for myopia. Refract Corneal Surg. 1993;9:S65-S70.
13. Azar DT, Jain S. Topical MMC for subepithelial fibrosis after corneal refractive surgery. Ophthalmology. 2001;108:239-240.
14. Epstein RJ, Majmudar PA. Alternative approach to the treatment of subepithelial fibrosis following radial keratotomy. Arch Ophthalmol. 2006;124:288.
15. Carones F, Vigo L, Scandola E, Vacchini L. Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy. J Cataract Refract Surg. 2002;28:2088-2095.
16. Lee DH, Chung HS, Jeon YC, Boo SD, Yoon YD, Kim JG. Photorefractive keratectomy with intraoperative mitomycin-C application. J Cataract Refract Surg. 2005;31:2293-2298.
17. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E. Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Ophthalmology. 2005;113:208-218.
18. Netto MV, Mohan RR, Sinha S, Sharma A, Gupta PC, Wilson SE. Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. J Refract Surg. 2006;22:562-574.
19. Kim T, Sorenson AL, Krishnasamy S, Carlson AN, Edelhauser HF. Acute corneal endothelial changes after laser in situ keratomileusis. Cornea. 2001;20:597-602.
20. Collins MJ, Carr JD, Stulting RD, Azar RG, Waring GO, Smith RE, Thompson KP, Edelhauser HF. Effects of laser in situ keratomileusis (LASIK) on the corneal endothelium 3 years post-operatively. Am J Ophthalmol. 2001;131:1-6.