Defect of regulatory T cells in patients with Omenn syndrome

Journal of Allergy and Clinical Immunology

Volumn 125, Issue 1-3, 2010, Pages 209-216

  Cassani, Barbara ^a   Poliani, Pietro Luigi ^b   Moratto, Daniele ^b   Sobacchi, Cristina ^a,c   Marrella, Veronica ^a,c   Imperatori, Laura ^b   Vairo, Donatella ^b   Plebani, Alessandro ^b   Giliani, Silvia ^b   Vezzoni, Paolo ^a,c   Facchetti, Fabio ^b   Porta, Fulvio ^b   Notarangelo, Luigi D ^d   Villa, Anna ^c,e   Badolato, Raffaele ^b  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c CNR   (Italy)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

Author keywords

anergy and tolerance; FOXP3; Immunodeficiency; Omenn syndrome; regulatory T cells; thymus and the development of T lymphocytes; V(D)J recombination

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL FRACTIONATION; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGICAL TOLERANCE; IMMUNOPHENOTYPING; LYMPH NODE; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; OMENN SYNDROME; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; THYMUS;

AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; HOMEODOMAIN PROTEINS; HUMANS; INFANT, NEWBORN; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPH NODES; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 73149109976     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.10.023     Document Type: Article

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