Oligoclonal expansion of CD45RO+ T lymphocytes in Omenn syndrome

Journal of Clinical Immunology

Volumn 17, Issue 4, 1997, Pages 322-332

  Harville, Terry O ^a   Adams, Denise M ^a   Howard, Thad A ^a   Ware, Russell E ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cytokines; Omenn syndrome; T cell receptor; T lymphocytes; T(H)1 cells; T(H)2 cells

Indexed keywords

CD45 ANTIGEN; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5;

ARTICLE; CASE REPORT; COMBINED IMMUNODEFICIENCY; EOSINOPHILIA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOPATHOGENESIS; IMMUNOSTIMULATION; INFANT; LYMPHOCYTE CLONE; MALE; OMENN SYNDROME; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

AMINO ACIDS; ANTIGENS, CD45; CLONE CELLS; CYTOKINES; DERMATITIS, EXFOLIATIVE; EOSINOPHILIA; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; IMMUNOGLOBULIN E; INFANT, NEWBORN; LYMPHOCYTOSIS; MALE; MULTIGENE FAMILY; PROTEIN BIOSYNTHESIS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SEVERE COMBINED IMMUNODEFICIENCY; SYNDROME; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH2 CELLS;

EID: 0030806253     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1027330800085     Document Type: Article

References (65)

1. Omenn GS: Familial reticuloendotheliosis with eosinophilia. N Engl J Med 273:427-432, 1965
2. Ochs HD, Davis SD, Mickelson E, Lerner KG, Wedgwood RJ: Combined immunodeficiency and reticuloendotheliosis with eosinophilia. J Pediatr 85:463-465, 1974
3. Velders AJ, Kuis W, van Dijk HA, Poppema S, Elema JD, Klokke AH, van Voorst Vader PC: Omenn syndrome: Familial reticuloendotheliosis with eosinophilia and combined immunodeficiency. Br J Dermatol 108:118-120, 1983
4. Ruco LP, Stoppacciaro A, Pezzella F, Mirolo M, Uccini S, Barsotti P, Cassano AM, Boner AL, Businco L, DiFazio A, Baroni CD: The Omenn's syndrome: Histological, immunohistochemical and ultrastructural evidence tor a partial T cell deficiency evolving in an abnormal proliferation of T lymphocytes and S-100+/T-6+ Langerhans-like cells. Virchow Arch [A] 407:69-82, 1985
5. Morren M, Van Lierde S, Lacquet F, Ceuppens JL, Delabie J, Dewolf-Peeters C, Degreef H: A case of Omenn-like immunodeficiency syndrome. Dermatology 185:302-304, 1992
6. Cederbaum SD, Niwayama G, Stiehm ER, Neerhout RC, Ammann AJ, Berman W: Combined immunodeficiency presenting as the Letterer-Siwe syndrome. J Pediatr 85:466-471, 1974
7. Jouan H, Le Deist F, Nezelof C: Omenn's syndrome - Pathologic arguments in favor of a graft versus host pathogenesis: A report of nine cases. Hum Pathol 18:1101-1108, 1987
8. Barth RF, Vergara GG, Khurana SK, Lowman JT, Beckwith JB: Rapidly fatal familial histiocytosis associated with eosinophilia and primary immunological deficiency. Lancet 2:503-506, 1972
9. Tachinami T, Koizumi S, Yachie A, Yamagami M, Yokoi T, Ohno I, Taniguchi N, Takada I, Kawashima A, Okada Y: Immune status in two brothers with Omenn's syndrome: No discernible chimerism on FACS analysis using a monoclonal antibody specific for a maternally restricted HLA antigen. Am J Pediatr Hematol Oncol 12:343-350, 1990
10. H2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 7:145-173, 1989
11. Schandene L, Ferster A, Mascart-Lemone F, Crusiaux A, Gerard C, Marchant A, Lybin M, Velu T, Sariban E, Goldman M: T helper type 2-like cells and therapeutic effects of interferon-γ in combined immunodeficiency with hypereosinophilia (Omenn's syndrome). Eur J Immunol 23:56-60, 1993
12. Karol RA, Eng J, Cooper JB, Dennison DK, Sawyer MK, Lawrence EC, Marcus DM, Shearer WT: Imbalances in subsets of T lymphocytes in an inbred pedigree with Omenn's syndrome. Clin Immunol Immunopathol 27:412-427, 1983
13. de Saint-Basile G, Le Deist F, de Villartay JP, Cerf-Bensussan N, Journet O, Brousse N, Griscelli C, Fischer A: Restricted heterogeneity of T lymphocytes in combined immunodeficiency with hypereosinophilia (Omenn's syndrome). J Clin Invest 87:1352-1359, 1991
14. Wirt DP, Brooks EG, Vaidya S, Klimpel GR, Waldmann TA, Goldblum RM: Novel T-lymphocyte population in combined immunodeficiency with features of graft-versus-host disease. N Engl J Med 321:370-374, 1989
15. - T cell population expressing high levels of IL-5 in Omenn's syndrome. Clin Exp Immunol 95:14-21, 1994
16. Rieux-Laucat F, Le Deist F, Hivroz C, Roberts IA, Debatin KM, Fischer A, de Villartay JP: Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268: 1347-1349, 1995
17. Fisher GH, Rosenberg FJ, Straus SE, Dale JK, Middleton LA, Lin AY, Strober W, Lenardo MJ, Puck JM: Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81:935-946, 1995
18. - lymphocyte subpopulation. J Immunol 154:4294-4301, 1995
19. Prussin C, Metcalfe DD: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods 188:117-128, 1995
20. Buckley RH, Schiff SE, Sampson HA, Schiff RI, Markert ML, Knutsen AP, Hershfield MS, Huang AT, Mickey GH, Ward FE: Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation. J Immunol 136:2398-2407, 1986
21. Ware RE, Hart MK, Haynes BF: Induction of T cell CD7 gene transcription by non-mitogenic ionomycin-induced transmembrane calcium flux. J Immunol 147:2787-2794, 1991
22. Wilson RK, Lai E, Kim LD, Hood L: Sequence and expression of a novel human T-cell receptor β-chain variable gene segment subfamily. Immunogenetics 32:406-412, 1990
23. Ferradini L, Roman-Roman S, Azocar J, Michalaki H, Triebel F, Hercend T: Studies on the human T cell receptor α/β variable region genes. II. Identification of four additional Vβ subfamilies. Eur J Immunol 21:935-942, 1991
24. Plaza A, Kono DH, Theofilopoulous AN: New human Vβ genes and polymorphic variants. J Immunol 147:4360-4365, 1991
25. Wei S, Charmley P, Robinson MA, Concannon P: The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenelics 40:27-36, 1994
26. Winter SS, Hanissian GA, Harville TO, Ware RE: Tumor necrosis factor-α supresses hematopoiesis in children with myelodysplasia. Med Pediatr Oncol 28:69-74, 1997
27. Ware RE, Rosse WF, Howard TA: Mutations within the Piga gene in patients with paroxysmal nocturnal hemoglobinuria. Blood 83:2418-2422, 1994
28. George JF Jr, Schroeder HW Jr: Developmental regulation of Dβ reading frame and junctional diversity in T cell receptor-β transcripts from human thymus. J Immunol 148:1230-1239, 1992
29. Bonati A, Zanelli P, Ferrari S, Plebani A, Starcich B, Savi M, Neri TM: T-cell receptor β-chain gene rearrangement and expression during human thymic ontogenesis. Blood 79:1472-1483, 1992
30. Sleasman JW, Harville TO, White GB, George JF, Barrett DJ, Goodenow MM: Arrested rearrangement of TCR Vβ genes in thymocytes from children with X-linked severe combined immunodeficiency disease. J Immunol 153:442-448, 1994
31. Breit TM, van Dongen JJ: Unraveling human T-cell receptor junctional region sequences. Thymus 222:177-199, 1994
32. Akolkar PN, Gulwani-Akolkar B, McKinley M, Fisher SE, Silver J: Comparisons of T cell receptor (TCR) Vβ repertoires of lamina propria and peripheral blood lymphocytes with respect to frequency and oligoclonality. Clin Immunol Immunopathol 76:155-163, 1995
33. Even J, Lim A, Puisieux I, Ferradini L, Dietrich PY, Toubert A, Hercend T, Triebel F, Pannetier C, Kourilsky P: T-cell repertoires in healthy and diseased human tissues analyzed by T-cell receptor β-chain CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases. Res Immunol 146: 65-80, 1995
34. Moller DR, Konishi K, Kirby M, Balbi B, Crystal RG: Bias toward use of a specific T cell receptor β chain variable region in subgroup of individuals with sarcoidosis. J Clin Invest 82:1183-1191, 1988
35. Seboun E, Robinson MA, Doolittle TH, Ciulla TA, Kindt TJ, Mauser SL: A susceptibility locus for multiple sclerosis is linked to the T cell receptor beta chain complex. Cell 57:1095-1100, 1989
36. Davey MP, Munkirs DD: Patterns of T-cell receptor variable beta gene expression by synovial fluid and peripheral blood T-cells in rheumatoid arthritis. Clin Immunol Immunopathol 68:79-87, 1993
37. Posnett DN, Schmelkin I, Burton DA, August A, McGrath H, Mayer LF: T cell antigen receptor V gene usage. Increases in Vβ8+ T cells in Crohn's disease. J Clin Invest 85:1770-1776, 1990
38. Kotzin BL, Karuturi S, Chou YK, Lafferty J, Forrester JM, Better M, Nedwin GE, Offner H, Vandenbark AA: Preferential T-cell receptor β-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis. Proc Natl Acad Sci USA 88:9161-9165, 1991
39. Dayan CM, Londei M, Corcoran AE, Grubeck-Loebenstein B, James RF, Rapoport B, Feldmann M: Autoantigen recognition by thyroid-infiltrating T cells in Graves disease. Proc Natl Acad Sci USA 88:7415-7419, 1991
40. Viale M, Merli A, Bacigalupo A: Analysis at the clonal level of T cell phenotype and functions in severe aplastic anemia patients. Blood 78:1268-1274, 1991
41. Ware RE, Howard TA: Phenotypic and clonal analysis of T lymphocytes in childhood immune thrombocytopenic purpura. Blood 82:2137-2142, 1993
42. + T cells with restricted T-cell receptor beta chain variability after bone marrow transplantation. Blood 83:587-595, 1994
43. + subset. J Immunol 154:6182-6190, 1995
44. Regnault A, Kourilsky P, Cumano A: The TCR-beta chain repertoire of gut-derived T lymphocytes. Semin Immunol 7:307-319, 1995
45. + intestinal mucosa T cells in ulcerative colitis. J Immunol 156:3024-3035, 1996
46. + T cell population of rheumatoid arthritis patients. J Immunol 156:852-858, 1996
47. Jones CM, Lake RA, Wijeyekoon JB, Mitchell DM, du Bois RM, O'Hehir RE: Oligoclonal V gene usage by T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients. Am J Resp Cell Mol Biol 14:470-477, 1996
48. Kumar A, Farace F, Gaudin C, Triebel F: Clonal T cell expansion induced by interleukin 2 therapy in blood and tumors. J Clin Invest 97:1219-1226, 1996
49. Masuko K, Kato S, Hagihara M, Tsuchida F, Takemoto Y, Izawa K, Kato T, Yamamori S, Mizushima Y, Nishioka K, Tsuji K, Yamamoto K: Stable clonal expansion of T cells induced by hone marrow transplantation. Blood 87:789-799, 1996
50. Puisieux I, Bain C, Merrouche Y, Malacher P, Kourilsky P, Even J, Favrot M: Restriction of the T-cell repertoire in tumor-infiltrating lymphocytes from nine patients with renal-cell carcinoma. Relevance of the CDR3 length analysis for the identification of in situ clonal T-cell expansions. Int J Cancer 66:201-208, 1996
51. + subset in normal human subjects. J Immunol 151:5762-5769, 1993
52. Sottini A, Quiros-Roidan E, Notarangelo LD, Malagoli A, Primi D, Imberti L: Engrafted maternal T cells in a severe combined immunodeficiency patient express T-cell receptor variable beta segments characterized by a restricted V-D-J junctional diversity. Blood 85:2105-2113, 1995
53. Kappler J, Kotzin B, Herron L, Gelfand EW, Bigler RD, Boylston A, Carrel S, Posnett DN, Choi Y, Marrack P: Vβ-specific stimulation of human T cells by staphylococcal toxins. Science 244: 811-813, 1989
54. Choi Y, Lafferty JA, Clements JR, Tood JK, Gelfand EW, Kappler J, Marrack P, Kotzin B: Selective expansion of cells expressing Vβ2 in toxic shock syndrome. J Exp Med 172:981-984, 1990
55. Marrack P, Kappler J: The staphylococcal enterotoxins and their relatives. Science 248:1066, 1990
56. Fink PJ, Blair MJ, Matis LA, Hedricks SM: Molecular analysis of the influences of positive selection, tolerance induction, and antigen presentation on the T cell receptor repertoire. J Exp Med 172:139-150, 1990
57. Ferber I, Schonrich G, Schenkel J, Mellor AL, Hammerling GJ, Arnold B: Levels of peripheral T cell tolerance induced by different doses of tolerogen. Science 263:674-676, 1994
58. Golstein P, Ojcius DM, Young JD: Cell death mechanisms and the immune system. Immunol Rev 121:29-55, 1991
59. Wesselborg S, Junsson O, Kabelitz D: Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J Immunol 150:4338-4345, 1993
60. Taga K, Cherney B, Tosato G: IL-10 inhibits apoptotic cell death in human T cells starved of IL-2. Int Immunol 5:1599-1608, 1993
61. Hong R, Gilbert FF, Opitz JM: Omenn disease: Termination in lymphoma. Pediatr Pathol 3:144-154, 1985
62. Reiner SL, Wang ZE, Hatam F, Scott P, Locksley RM: Th1 and Th2 cell antigen receptors in experimental leishmaniasis. Science 259:1457-1460, 1993
63. Friedrich V, Goldmann SF, Ebell W, Blutters-Sawatzki R, Gaedicke G, Raghavachar A, Peter HH, Belohradsky B, Kreth V, Kubanek B, Kleihauer E: Severe combined immunodeficiency: Treatment by hone marrow transplantation in 15 infants using HLA-haploidentical donors. Eur J Podialr 144:125-130, 1985
64. Junker AK, Chan KW, Massing BG: Clinical and immune recovery from Omenn syndrome alter bone marrow transplantation. J Pediatr 114:596-600, 1989
65. Heyderman RS, Morgan G, Levinsky RJ, Strobel S: Successful bone marrow transplantation and treatment ot BCG infection in two patients with severe combined immunodeficiency. Eur J Pediatr 150:477-480, 1991