Activation of Cdk4 and Cdk2 during rat liver regeneration is associated with intranuclear rearrangements of cyclin-cdk complexes

Hepatology

Volumn 29, Issue 2, 1999, Pages 385-395

  Jaumot, Montserrat ^a   Estanyol, Josef Maria ^a   Serratosa, Joan ^b   Agell, Neus ^a   Bachs, Oriol ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Instituto de Investigaciones   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEMIHEPATECTOMY; IMMUNOCYTOCHEMISTRY; LIVER REGENERATION; MALE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM;

ANIMALS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CELL NUCLEUS; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; ENZYME INHIBITORS; G1 PHASE; HEPATECTOMY; IMMUNOHISTOCHEMISTRY; KINETICS; LIVER; LIVER REGENERATION; MALE; MICROTUBULE-ASSOCIATED PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; S PHASE; TUMOR SUPPRESSOR PROTEINS;

EID: 0032985495     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510290226     Document Type: Article

References (14)

1. Higgings GM, Anderson RM. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931;12:186-202.
2. Steer CJ. Liver regeneration. FASEB J 1995;9:1396-1400.
3. Michalopoulos GK, DeFrances MC. Liver regeneration. Science 1997;276:60-66.
4. Mead JE, Fausto N. Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc Natl Acad Sci U S A 1989;86:1558-1562.
5. Skov-Olsen P, Boesby S, Kirkegaard P, Therkelsen K, Almdal T, Poulsen SS, Nexo E. Influence of epidermal growth factor on liver regeneration after partial hepatectomy in rats. HEPATOLOGY 1988;8:992-996.
6. Lindroos PM, Zarnegar R, Michalopoulos GK. Hepatocyte growth factor (hepatopoietin A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulated by partial hepatectomy and carbon tetrachloride administration. HEPATOLOGY 1991;13:743-750.
7. Fausto N, Laird AD, Webber EM. Role of growth factors and cytokines in hepatic regeneration. FASEB J 1995;9:1527-1536.
8. Yamada Y, Kirillova I, Peschon JJ, Fausto N. Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proc Natl Acad Sci U S A 1997;94:1441-1446.
9. Sherr CJ. G1 phase progression: cycling on cue. Cell 1994;79:551-556.
10. Pines J. Cyclins and cyclin-dependent kinases: a biochemical view. Biochem J 1995;308:697-711.
11. Graña X, Reddy PE. Cell cycle control in mammalian cells: role of cyclins, cyclin-dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 1995;11:211-219.
12. Morgan DO. Principles of CDK regulation. Nature 1995;374:131-134.
13. Sclafani RA. Cyclin dependent kinase activating kinases. Curr Opin Cell Biol 1996;8:788-794.
14. Lew DL, Kornbluth S. Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. Curr Opin Cell Biol 1996;8:795-804.