-
1
-
-
23144451917
-
Cdc2-cyclin E complexes regulate the G1/S phase transition
-
Aleem E, Kiyokawa H, Kaldis P (2005) Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol 7: 831-836
-
(2005)
Nat Cell Biol
, vol.7
, pp. 831-836
-
-
Aleem, E.1
Kiyokawa, H.2
Kaldis, P.3
-
2
-
-
0142116249
-
Cdk2 knockout mice are viable
-
Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P (2003) Cdk2 knockout mice are viable. Curr Biol 13: 1775-1785
-
(2003)
Curr Biol
, vol.13
, pp. 1775-1785
-
-
Berthet, C.1
Aleem, E.2
Coppola, V.3
Tessarollo, L.4
Kaldis, P.5
-
3
-
-
0022981734
-
Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs
-
Blow JJ, Laskey RA (1986) Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell 47: 577-587
-
(1986)
Cell
, vol.47
, pp. 577-587
-
-
Blow, J.J.1
Laskey, R.A.2
-
4
-
-
0025073063
-
A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts
-
Blow JJ, Nurse P (1990) A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts. Cell 62: 855-862
-
(1990)
Cell
, vol.62
, pp. 855-862
-
-
Blow, J.J.1
Nurse, P.2
-
5
-
-
0035825156
-
Replication origins in Xenopus egg extract are 5-15 kilobases apart and are activated in clusters that fire at different times
-
Blow JJ, Gillespie PJ, Francis D, Jackson DA (2001) Replication origins in Xenopus egg extract are 5-15 kilobases apart and are activated in clusters that fire at different times. J Cell Biol 152: 15-25
-
(2001)
J Cell Biol
, vol.152
, pp. 15-25
-
-
Blow, J.J.1
Gillespie, P.J.2
Francis, D.3
Jackson, D.A.4
-
6
-
-
0029015715
-
Both cdc2 and cdk2 promote S phase initiation in Xenopus egg extracts
-
Chevalier S, Tassan JP, Cox R, Philippe M, Ford C (1995) Both cdc2 and cdk2 promote S phase initiation in Xenopus egg extracts. J Cell Sci 108 (Part 5): 1831-1841
-
(1995)
J Cell Sci
, vol.108
, Issue.PART 5
, pp. 1831-1841
-
-
Chevalier, S.1
Tassan, J.P.2
Cox, R.3
Philippe, M.4
Ford, C.5
-
7
-
-
0036305474
-
Distinct roles for cyclins E and A during DNA replication complex assembly and activation
-
Coverley D, Laman H, Laskey RA (2002) Distinct roles for cyclins E and A during DNA replication complex assembly and activation. Nat Cell Biol 4: 523-528
-
(2002)
Nat Cell Biol
, vol.4
, pp. 523-528
-
-
Coverley, D.1
Laman, H.2
Laskey, R.A.3
-
8
-
-
0036785882
-
Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor
-
Davies TG, Bentley J, Arris CE, Boyle FT, Curtin NJ, Endicott JA, Gibson AE, Golding BT, Griffin RJ, Hardcastle IR, Jewsbury P, Johnson LN, Mesguiche V, Newell DR, Noble ME, Tucker JA, Wang L, Whitfield HJ (2002) Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor. Nat Struct Biol 9: 745-749
-
(2002)
Nat Struct Biol
, vol.9
, pp. 745-749
-
-
Davies, T.G.1
Bentley, J.2
Arris, C.E.3
Boyle, F.T.4
Curtin, N.J.5
Endicott, J.A.6
Gibson, A.E.7
Golding, B.T.8
Griffin, R.J.9
Hardcastle, I.R.10
Jewsbury, P.11
Johnson, L.N.12
Mesguiche, V.13
Newell, D.R.14
Noble, M.E.15
Tucker, J.A.16
Wang, L.17
Whitfield, H.J.18
-
9
-
-
0032134456
-
CLB5-dependent activation of late replication origins in S. cerevisiae
-
Donaldson AD, Raghuraman MK, Friedman KL, Cross FR, Brewer BJ, Fangman WL (1998) CLB5-dependent activation of late replication origins in S. cerevisiae. Mol Cell 2: 173-182
-
(1998)
Mol Cell
, vol.2
, pp. 173-182
-
-
Donaldson, A.D.1
Raghuraman, M.K.2
Friedman, K.L.3
Cross, F.R.4
Brewer, B.J.5
Fangman, W.L.6
-
10
-
-
0025831974
-
Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes
-
Fang F, Newport JW (1991) Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell 66: 731-742
-
(1991)
Cell
, vol.66
, pp. 731-742
-
-
Fang, F.1
Newport, J.W.2
-
11
-
-
0029670828
-
A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins
-
Fisher DL, Nurse P (1996) A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins. EMBO J 15: 850-860
-
(1996)
EMBO J
, vol.15
, pp. 850-860
-
-
Fisher, D.L.1
Nurse, P.2
-
12
-
-
0035911969
-
Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication
-
Furstenthal L, Kaiser BK, Swanson C, Jackson PK (2001) Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. J Cell Biol 152: 1267-1278
-
(2001)
J Cell Biol
, vol.152
, pp. 1267-1278
-
-
Furstenthal, L.1
Kaiser, B.K.2
Swanson, C.3
Jackson, P.K.4
-
13
-
-
33846018073
-
Kinase-independent function of cyclin E
-
Geng Y, Lee YM, Welcker M, Swanger J, Zagozdzon A, Winer JD, Roberts JM, Kaldis P, Clurman BE, Sicinski P (2007) Kinase-independent function of cyclin E. Mol Cell 25: 127-139
-
(2007)
Mol Cell
, vol.25
, pp. 127-139
-
-
Geng, Y.1
Lee, Y.M.2
Welcker, M.3
Swanger, J.4
Zagozdzon, A.5
Winer, J.D.6
Roberts, J.M.7
Kaldis, P.8
Clurman, B.E.9
Sicinski, P.10
-
14
-
-
0042528364
-
Cyclin E ablation in the mouse
-
Geng Y, Yu Q, Sicinska E, Das M, Schneider JE, Bhattacharya S, Rideout WM, Bronson RT, Gardner H, Sicinski P (2003) Cyclin E ablation in the mouse. Cell 114: 431-443
-
(2003)
Cell
, vol.114
, pp. 431-443
-
-
Geng, Y.1
Yu, Q.2
Sicinska, E.3
Das, M.4
Schneider, J.E.5
Bhattacharya, S.6
Rideout, W.M.7
Bronson, R.T.8
Gardner, H.9
Sicinski, P.10
-
15
-
-
0037900888
-
Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication
-
Hashimoto Y, Takisawa H (2003) Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication. EMBO J 22: 2526-2535
-
(2003)
EMBO J
, vol.22
, pp. 2526-2535
-
-
Hashimoto, Y.1
Takisawa, H.2
-
16
-
-
0034725550
-
Replication fork density increases during DNA synthesis in X. laevis egg extracts
-
Herrick J, Stanislawski P, Hyrien O, Bensimon A (2000) Replication fork density increases during DNA synthesis in X. laevis egg extracts. J Mol Biol 300: 1133-1142
-
(2000)
J Mol Biol
, vol.300
, pp. 1133-1142
-
-
Herrick, J.1
Stanislawski, P.2
Hyrien, O.3
Bensimon, A.4
-
17
-
-
0028829358
-
Transition in specification of embryonic metazoan DNA replication origins
-
Hyrien O, Maric C, Mechali M (1995) Transition in specification of embryonic metazoan DNA replication origins. Science 270: 994-997
-
(1995)
Science
, vol.270
, pp. 994-997
-
-
Hyrien, O.1
Maric, C.2
Mechali, M.3
-
18
-
-
34447558662
-
An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells
-
Hochegger H, Dejsuphong D, Sonoda E, Saberi A, Rajendra E, Kirk J, Hunt T, Takeda S (2007) An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells. J Cell Biol 178: 257-268
-
(2007)
J Cell Biol
, vol.178
, pp. 257-268
-
-
Hochegger, H.1
Dejsuphong, D.2
Sonoda, E.3
Saberi, A.4
Rajendra, E.5
Kirk, J.6
Hunt, T.7
Takeda, S.8
-
19
-
-
0029125622
-
Early events in DNA replication require cyclin E and are blocked by p21CIP1
-
Jackson PK, Chevalier S, Philippe M, Kirschner MW (1995) Early events in DNA replication require cyclin E and are blocked by p21CIP1. J Cell Biol 130: 755-769
-
(1995)
J Cell Biol
, vol.130
, pp. 755-769
-
-
Jackson, P.K.1
Chevalier, S.2
Philippe, M.3
Kirschner, M.W.4
-
20
-
-
0035873249
-
A complex degradation signal in cyclin A required for G1 arrest, and a C-terminal region for mitosis
-
Jacobs HW, Keidel E, Lehner CF (2001) A complex degradation signal in cyclin A required for G1 arrest, and a C-terminal region for mitosis. EMBO J 20: 2376-2386
-
(2001)
EMBO J
, vol.20
, pp. 2376-2386
-
-
Jacobs, H.W.1
Keidel, E.2
Lehner, C.F.3
-
21
-
-
0034659412
-
Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading
-
Jares P, Blow JJ (2000) Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading. Genes Dev 14: 1528-1540
-
(2000)
Genes Dev
, vol.14
, pp. 1528-1540
-
-
Jares, P.1
Blow, J.J.2
-
22
-
-
0028358931
-
Cyclin E controls S phase progression and its downregulation during Drosophila embryogenesis is required for the arrest of cell proliferation
-
Knoblich JA, Sauer K, Jones L, Richardson H, Saint R, Lehner CF (1994) Cyclin E controls S phase progression and its downregulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell 77: 107-120
-
(1994)
Cell
, vol.77
, pp. 107-120
-
-
Knoblich, J.A.1
Sauer, K.2
Jones, L.3
Richardson, H.4
Saint, R.5
Lehner, C.F.6
-
24
-
-
0026395073
-
Cyclins and their partners during Xenopus oocyte maturation
-
Kobayashi H, Golsteyn R, Poon R, Stewart E, Gannon J, Minshull J, Smith R, Hunt T (1991) Cyclins and their partners during Xenopus oocyte maturation. Cold Spring Harb Symp Quant Biol 56: 437-447
-
(1991)
Cold Spring Harb Symp Quant Biol
, vol.56
, pp. 437-447
-
-
Kobayashi, H.1
Golsteyn, R.2
Poon, R.3
Stewart, E.4
Gannon, J.5
Minshull, J.6
Smith, R.7
Hunt, T.8
-
25
-
-
28344440877
-
Mitotic remodeling of the replicon and chromosome structure
-
Lemaitre JM, Danis E, Pasero P, Vassetzky Y, Mechali M (2005) Mitotic remodeling of the replicon and chromosome structure. Cell 123: 787-801
-
(2005)
Cell
, vol.123
, pp. 787-801
-
-
Lemaitre, J.M.1
Danis, E.2
Pasero, P.3
Vassetzky, Y.4
Mechali, M.5
-
26
-
-
14544270984
-
Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates
-
Loog M, Morgan DO (2005) Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 434: 104-108
-
(2005)
Nature
, vol.434
, pp. 104-108
-
-
Loog, M.1
Morgan, D.O.2
-
27
-
-
0034711945
-
Mechanisms ensuring rapid and complete DNA replication despite random initiation in Xenopus early embryos
-
Lucas I, Chevrier-Miller M, Sogo JM, Hyrien O (2000) Mechanisms ensuring rapid and complete DNA replication despite random initiation in Xenopus early embryos. J Mol Biol 296: 769-786
-
(2000)
J Mol Biol
, vol.296
, pp. 769-786
-
-
Lucas, I.1
Chevrier-Miller, M.2
Sogo, J.M.3
Hyrien, O.4
-
28
-
-
12344254254
-
Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus
-
Luciani MG, Oehlmann M, Blow JJ (2004) Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus. J Cell Sci 117: 6019-6030
-
(2004)
J Cell Sci
, vol.117
, pp. 6019-6030
-
-
Luciani, M.G.1
Oehlmann, M.2
Blow, J.J.3
-
29
-
-
0035907338
-
Aphidicolin triggers a block to replication origin firing in Xenopus egg extracts
-
Marheineke K, Hyrien O (2001) Aphidicolin triggers a block to replication origin firing in Xenopus egg extracts. J Biol Chem 276: 17092-17100
-
(2001)
J Biol Chem
, vol.276
, pp. 17092-17100
-
-
Marheineke, K.1
Hyrien, O.2
-
30
-
-
3142544855
-
Control of replication origin density and firing time in Xenopus egg extracts: Role of a caffeine-sensitive, ATR-dependent checkpoint
-
Marheineke K, Hyrien O (2004) Control of replication origin density and firing time in Xenopus egg extracts: role of a caffeine-sensitive, ATR-dependent checkpoint. J Biol Chem 279: 28071-28081
-
(2004)
J Biol Chem
, vol.279
, pp. 28071-28081
-
-
Marheineke, K.1
Hyrien, O.2
-
31
-
-
13044316665
-
Dynamic molecular combing: Stretching the whole human genome for high-resolution studies
-
Michalet X, Ekong R, Fougerousse F, Rousseaux S, Schurra C, Hornigold N, van Slegtenhorst M, Wolfe J, Povey S, Beckmann JS, Bensimon A (1997) Dynamic molecular combing: stretching the whole human genome for high-resolution studies. Science 277: 1518-1523
-
(1997)
Science
, vol.277
, pp. 1518-1523
-
-
Michalet, X.1
Ekong, R.2
Fougerousse, F.3
Rousseaux, S.4
Schurra, C.5
Hornigold, N.6
van Slegtenhorst, M.7
Wolfe, J.8
Povey, S.9
Beckmann, J.S.10
Bensimon, A.11
-
32
-
-
0037655970
-
Unmasking the S-phase-promoting potential of cyclin B1
-
Moore JD, Kirk JA, Hunt T (2003) Unmasking the S-phase-promoting potential of cyclin B1. Science 300: 987-990
-
(2003)
Science
, vol.300
, pp. 987-990
-
-
Moore, J.D.1
Kirk, J.A.2
Hunt, T.3
-
33
-
-
1842843544
-
Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis
-
Moore JD, Kornbluth S, Hunt T (2002) Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis. Mol Biol Cell 13: 4388-4400
-
(2002)
Mol Biol Cell
, vol.13
, pp. 4388-4400
-
-
Moore, J.D.1
Kornbluth, S.2
Hunt, T.3
-
34
-
-
0032529574
-
Cdk2 activity is dispensable for the onset of DNA replication during the first mitotic cycles of the sea urchin early embryo
-
Moreau JL, Marques F, Barakat A, Schatt P, Lozano JC, Peaucellier G, Picard A, Geneviere AM (1998) Cdk2 activity is dispensable for the onset of DNA replication during the first mitotic cycles of the sea urchin early embryo. Dev Biol 200: 182-197
-
(1998)
Dev Biol
, vol.200
, pp. 182-197
-
-
Moreau, J.L.1
Marques, F.2
Barakat, A.3
Schatt, P.4
Lozano, J.C.5
Peaucellier, G.6
Picard, A.7
Geneviere, A.M.8
-
35
-
-
0025246110
-
Universal control mechanism regulating onset of M-phase
-
Nurse P (1990) Universal control mechanism regulating onset of M-phase. Nature 344: 503-508
-
(1990)
Nature
, vol.344
, pp. 503-508
-
-
Nurse, P.1
-
36
-
-
0041854279
-
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
-
Ortega S, Prieto I, Odajima J, Martin A, Dubus P, Sotillo R, Barbero JL, Malumbres M, Barbacid M (2003) Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet 35: 25-31
-
(2003)
Nat Genet
, vol.35
, pp. 25-31
-
-
Ortega, S.1
Prieto, I.2
Odajima, J.3
Martin, A.4
Dubus, P.5
Sotillo, R.6
Barbero, J.L.7
Malumbres, M.8
Barbacid, M.9
-
37
-
-
0141737069
-
Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells
-
Parisi T, Beck AR, Rougier N, McNeil T, Lucian L, Werb Z, Amati B (2003) Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells. EMBO J 22: 4794-4803
-
(2003)
EMBO J
, vol.22
, pp. 4794-4803
-
-
Parisi, T.1
Beck, A.R.2
Rougier, N.3
McNeil, T.4
Lucian, L.5
Werb, Z.6
Amati, B.7
-
38
-
-
0345700833
-
Building a cell cycle oscillator: Hysteresis and bistability in the activation of Cdc2
-
Pomerening JR, Sontag ED, Ferrell Jr JE (2003) Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat Cell Biol 5: 346-351
-
(2003)
Nat Cell Biol
, vol.5
, pp. 346-351
-
-
Pomerening, J.R.1
Sontag, E.D.2
Ferrell Jr, J.E.3
-
39
-
-
34547952048
-
Cdk1 is sufficient to drive the mammalian cell cycle
-
Santamaria D, Barrière C, Cerqueira A, Hunt S, Tardy C, Newton K, Cáceres J, Dubus P, Malumbres M, Barbacid M (2007) Cdk1 is sufficient to drive the mammalian cell cycle. Nature 448: 6046-6050
-
(2007)
Nature
, vol.448
, pp. 6046-6050
-
-
Santamaria, D.1
Barrière, C.2
Cerqueira, A.3
Hunt, S.4
Tardy, C.5
Newton, K.6
Cáceres, J.7
Dubus, P.8
Malumbres, M.9
Barbacid, M.10
-
40
-
-
34249706797
-
Cyclin E/Cdk2 is required for sperm maturation, but not DNA replication, in early sea urchin embryos
-
Schnackenberg BJ, Palazzo RE, Marzluff WF (2007) Cyclin E/Cdk2 is required for sperm maturation, but not DNA replication, in early sea urchin embryos. Genesis 45: 282-291
-
(2007)
Genesis
, vol.45
, pp. 282-291
-
-
Schnackenberg, B.J.1
Palazzo, R.E.2
Marzluff, W.F.3
-
41
-
-
0242708738
-
Small-molecule cyclin-dependent kinase modulators
-
Senderowicz AM (2003) Small-molecule cyclin-dependent kinase modulators. Oncogene 22: 6609-6620
-
(2003)
Oncogene
, vol.22
, pp. 6609-6620
-
-
Senderowicz, A.M.1
-
42
-
-
3242670803
-
ATR and ATM regulate the timing of DNA replication origin firing
-
Shechter D, Costanzo V, Gautier J (2004) ATR and ATM regulate the timing of DNA replication origin firing. Nat Cell Biol 6: 648-655
-
(2004)
Nat Cell Biol
, vol.6
, pp. 648-655
-
-
Shechter, D.1
Costanzo, V.2
Gautier, J.3
-
43
-
-
0033575920
-
Deregulated cyclin E induces chromosome instability
-
Spruck CH, Won KA, Reed SI (1999) Deregulated cyclin E induces chromosome instability. Nature 401: 297-300
-
(1999)
Nature
, vol.401
, pp. 297-300
-
-
Spruck, C.H.1
Won, K.A.2
Reed, S.I.3
-
44
-
-
0029891988
-
Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts
-
Strausfeld UP, Howell M, Descombes P, Chevalier S, Rempel RE, Adamczewski J, Maller JL, Hunt T, Blow JJ (1996) Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts. J Cell Sci 109: 1555-1563
-
(1996)
J Cell Sci
, vol.109
, pp. 1555-1563
-
-
Strausfeld, U.P.1
Howell, M.2
Descombes, P.3
Chevalier, S.4
Rempel, R.E.5
Adamczewski, J.6
Maller, J.L.7
Hunt, T.8
Blow, J.J.9
-
45
-
-
0041327168
-
Proliferation of cancer cells despite CDK2 inhibition
-
Tetsu O, McCormick F (2003) Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell 3: 233-245
-
(2003)
Cancer Cell
, vol.3
, pp. 233-245
-
-
Tetsu, O.1
McCormick, F.2
-
46
-
-
0032562610
-
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
-
Zou L, Stillman B (1998) Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280: 593-596
-
(1998)
Science
, vol.280
, pp. 593-596
-
-
Zou, L.1
Stillman, B.2
|