Pharmacological modulation of subliminal learning in Parkinson's and Tourette's syndromes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 45, 2009, Pages 19179-19184

  Palminteri, Stefano ^a,b   Lebreton, Maël ^a,b   Worbe, Yulia ^a,b   Grabli, David ^a,b,c   Hartmann, Andreas ^a,b,d   Pessiglione, Mathias ^a,b  

^a INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^d National Rare Disease Reference Center Gilles de la Tourette Syndrome   (France)

Author keywords

Dopamine; Instrumental learning; Punishment; Reward; Subliminal perception

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA; PIMOZIDE; RISPERIDONE;

ADULT; ARTICLE; ASSOCIATION; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; FEMALE; GILLES DE LA TOURETTE SYNDROME; HUMAN; LEARNING; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PRIORITY JOURNAL; REWARD; TASK PERFORMANCE; VISUAL DISCRIMINATION;

ADOLESCENT; ADULT; AVOIDANCE LEARNING; CONDITIONING (PSYCHOLOGY); CUES; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; FEMALE; HUMANS; LEVODOPA; MALE; MIDDLE AGED; PARKINSON DISEASE; PHOTIC STIMULATION; REWARD; RISPERIDONE; SUBLIMINAL STIMULATION; TOURETTE SYNDROME;

EID: 73149090095     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904035106     Document Type: Article

References (35)

1. Rescorla RA, Wagner AR (1972) A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement. Classical Conditioning II: Current Research and Theory, eds Black AH, Prokasy WF (Appleton-Century-Crofts, New York), pp 64-99.
2. Sutton RS, Barto AG (1998) Reinforcement Learning. (MIT Press, Cambridge, MA).
3. Daw ND, Doya K (2006) The computational neurobiology of learning and reward. Curr Opin Neurobiol 16(2):199-204.
4. O'Doherty JP, Hampton A, Kim H (2007) Model-based fMRI and its application to reward learning and decision making. Ann N Y Acad Sci 1104:35-53.
5. Schultz W, Dayan P, Montague PR (1997) A neural substrate of prediction and reward. Science 275(5306):1593-1599.
6. Waelti P, Dickinson A, Schultz W (2001) Dopamine responses comply with basic assumptions of formal learning theory. Nature 412(6842):43-48.
7. Pessiglione M, Seymour B, Flandin G, Dolan RJ, Frith CD (2006) Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans. Nature 442(7106):1042-1045.
8. Frank MJ, Seeberger LC, O'Reilly RC (2004) By carrot or by stick: Cognitive reinforcement learning in parkinsonism. Science 306(5703):1940-1943.
9. Cools R, Altamirano L, D'Esposito M (2006) Reversal learning in Parkinson's disease depends on medication status and outcome valence. Neuropsychologia 44(10):1663-1673.
10. Frank MJ (2005) Dynamic dopamine modulation in the basal ganglia: A neurocomputational account of cognitive deficits in medicated and nonmedicated Parkinsonism. J Cogn Neurosci 17(1):51-72.
11. Pessiglione M, et al. (2008) Subliminal instrumental conditioning demonstrated in the human brain. Neuron 59(4):561-567.
12. Kouider S, Dehaene S (2007) Levels of processing during non-conscious perception: A critical review of visual masking. Philos Trans R Soc Lond B Biol Sci 362(1481):857-875.
13. Dehaene S, Changeux JP, Naccache L, Sackur J, Sergent C (2006) Conscious, preconscious, and subliminal processing: A testable taxonomy. Trends Cogn Sci 10(5):204-211.
14. Knowlton BJ, Mangels JA, Squire LR (1996) A neostriatal habit learning system in humans. Science 273(5280):1399-1402.
15. Shohamy D, et al. (2004) Cortico-striatal contributions to feedback-based learning: Converging data from neuroimaging and neuropsychology. Brain 127(Pt 4):851-859.
16. Lagnado DA, Newell BR, Kahan S, Shanks DR (2006) Insight and strategy in multiple-cue learning. J Exp Psychol Gen 135(2):162-183.
17. Lovibond PF, Shanks DR (2002) The role of awareness in Pavlovian conditioning: Empirical evidence and theoretical implications. J Exp Psychol Anim Behav Process 28(1):3-26.
18. Wilkinson L, Shanks DR (2004) Intentional control and implicit sequence learning. J Exp Psychol Learn Mem Cogn 30(2):354-369.
19. Morris JS, Ohman A, Dolan RJ (1998) Conscious and unconscious emotional learning in the human amygdala. Nature 393(6684):467-470.
20. Olsson A, Phelps EA (2004) Learned fear of "unseen" faces after Pavlovian, observational, and instructed fear. Psychol Sci 15(12):822-828.
21. Knight DC, Nguyen HT, Bandettini PA (2003) Expression of conditional fear with and without awareness. Proc Natl Acad Sci USA 100(25):15280-15283.
22. Seitz AR, Kim D, Watanabe T (2009) Rewards evoke learning of unconsciously processed visual stimuli in adult humans. Neuron 61(5):700-707.
23. Li W, Howard JD, Parrish TB, Gottfried JA (2008) Aversive learning enhances perceptual and cortical discrimination of indiscriminable odor cues. Science 319(5871):1842-1845.
24. Braak H, Del Tredici K (2008) Invited article: Nervous system pathology in sporadic Parkinson disease. Neurology 70(20):1916-1925.
25. Pessiglione M, et al. (2005) An effect of dopamine depletion on decision-making: The temporal coupling of deliberation and execution. J Cogn Neurosci 17(12):1886-1896.
26. Voon V, Potenza MN, Thomsen T (2007) Medication-related impulse control and repetitive behaviors in Parkinson's disease. Curr Opin Neurol 20(4):484-492.
27. Lawrence AD, Evans AH, Lees AJ (2003) Compulsive use of dopamine replacement therapy in Parkinson's disease: Reward systems gone awry? Lancet Neurol 2(10):595-604.
28. Singer HS (2005) Tourette's syndrome: From behaviour to biology. Lancet Neurol 4(3):149-159.
29. Albin RL, Mink JW (2006) Recent advances in Tourette syndrome research. Trends Neurosci 29(3):175-182.
30. Leckman JF (2002) Tourette's syndrome. Lancet 360(9345):1577-1586.
31. Wong DF, et al. (2008) Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: Clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology 33(6):1239-1251.
32. Tarnok Z, et al. (2007) Dopaminergic candidate genes in Tourette syndrome: Association between tic severity and 3′ UTR polymorphism of the dopamine transporter gene. Am J Med Genet B Neuropsychiatr Genet 144B(7):900-905.
33. Gilbert DL, et al. (2006) Altered mesolimbocortical and thalamic dopamine in Tourette syndrome. Neurology 67(9):1695-1697.
34. Yoon DY, et al. (2007) Dopaminergic polymorphisms in Tourette syndrome: Association with the DAT gene (SLC6A3). Am J Med Genet B Neuropsychiatr Genet 144B(5):605-610.
35. Schmidt L, et al. (2008) Disconnecting force from money: Effects of basal ganglia damage on incentive motivation. Brain 131(Pt 5):1303-1310.