-
1
-
-
0344121735
-
Crossing the bridge: Large animal models in translational transplantation research
-
Kirk AD. Crossing the bridge: Large animal models in translational transplantation research. Immunol Rev 2003; 196: 176.
-
(2003)
Immunol Rev
, vol.196
, pp. 176
-
-
Kirk, A.D.1
-
2
-
-
33745235090
-
Transplant tolerance in non-human primates: Progress, current challenges and unmet needs
-
Kean LS, Gangappa S, Pearson TC, et al. Transplant tolerance in non-human primates: Progress, current challenges and unmet needs. Am J Transplant 2006; 6 (5 Pt 1): 884.
-
(2006)
Am J Transplant
, vol.6
, Issue.5 PART 1
, pp. 884
-
-
Kean, L.S.1
Gangappa, S.2
Pearson, T.C.3
-
4
-
-
17144374934
-
Regulatory T-cell therapy: Is it ready for the clinic?
-
Bluestone JA. Regulatory T-cell therapy: Is it ready for the clinic? Nat Rev Immunol 2005; 5: 343.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 343
-
-
Bluestone, J.A.1
-
5
-
-
34547150491
-
What does the future hold for cell-based tolerogenic therapy?
-
Bluestone JA, Thomson AW, Shevach EM, et al. What does the future hold for cell-based tolerogenic therapy? Nat Rev Immunol 2007; 7: 650.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 650
-
-
Bluestone, J.A.1
Thomson, A.W.2
Shevach, E.M.3
-
6
-
-
0037364976
-
Regulatory T cells in transplantation tolerance
-
Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3: 199.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 199
-
-
Wood, K.J.1
Sakaguchi, S.2
-
7
-
-
33846214275
-
In vitro-expanded donor alloantigen-specific CD4+CD25 + regulatory T cells promote experimental transplantation tolerance
-
Golshayan D, Jiang S, Tsang J, et al. In vitro-expanded donor alloantigen-specific CD4+CD25 + regulatory T cells promote experimental transplantation tolerance. Blood 2007; 109: 827.
-
(2007)
Blood
, vol.109
, pp. 827
-
-
Golshayan, D.1
Jiang, S.2
Tsang, J.3
-
8
-
-
38149050594
-
Ex vivo-expanded natural CD4+CD25 + regulatory T cells synergize with host T-cell depletion to promote long-term survival of allografts
-
Xia G, He J, Leventhal JR. Ex vivo-expanded natural CD4+CD25 + regulatory T cells synergize with host T-cell depletion to promote long-term survival of allografts. Am J Transplant 2008; 8: 298.
-
(2008)
Am J Transplant
, vol.8
, pp. 298
-
-
Xia, G.1
He, J.2
Leventhal, J.R.3
-
9
-
-
2542496868
-
Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes
-
Joffre O, Gorsse N, Romagnoli P, et al. Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes. Blood 2004; 103: 4216.
-
(2004)
Blood
, vol.103
, pp. 4216
-
-
Joffre, O.1
Gorsse, N.2
Romagnoli, P.3
-
10
-
-
0346690399
-
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
-
Trenado A, Charlotte F, Fisson S, et al. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J Clin Invest 2003; 112: 1688.
-
(2003)
J Clin Invest
, vol.112
, pp. 1688
-
-
Trenado, A.1
Charlotte, F.2
Fisson, S.3
-
11
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi S, Yamaguchi T, Nomura T, et al. Regulatory T cells and immune tolerance. Cell 2008; 133: 775.
-
(2008)
Cell
, vol.133
, pp. 775
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
-
12
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004; 22: 531.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531
-
-
Sakaguchi, S.1
-
14
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4: 330.
-
(2003)
Nat Immunol
, vol.4
, pp. 330
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
15
-
-
33646240855
-
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
-
Gavin MA, Torgerson TR, Houston E, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl AcadSci USA2006; 103:6659.
-
(2006)
Proc Natl AcadSci USA
, vol.103
, pp. 6659
-
-
Gavin, M.A.1
Torgerson, T.R.2
Houston, E.3
-
16
-
-
33846375082
-
Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells
-
Wang J, Ioan-Facsinay A, van der Voort EI, et al. Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells. Eur J Im-munol2007; 37: 129.
-
(2007)
Eur J Im-munol
, vol.37
, pp. 129
-
-
Wang, J.1
Ioan-Facsinay, A.2
Van Der Voort, E.I.3
-
17
-
-
85047692469
-
CD4+CD25+ regulatory T cells suppress allograft rejection mediated by memory CD8+ T cells via a CD30-dependent mechanism
-
Dai Z, Li Q, Wang Y, et al. CD4+CD25+ regulatory T cells suppress allograft rejection mediated by memory CD8+ T cells via a CD30-dependent mechanism. J Clin Invest 2004; 113: 310.
-
(2004)
J Clin Invest
, vol.113
, pp. 310
-
-
Dai, Z.1
Li, Q.2
Wang, Y.3
-
18
-
-
0036467522
-
CD25 + CD4+ regulatoryTcells prevent graft rejection: CTLA-4-and IL-10-dependent immunoregu-lation of alloresponses
-
KingsleyC, Karim M, Bushell A, et al. CD25 + CD4+ regulatoryTcells prevent graft rejection: CTLA-4-and IL-10-dependent immunoregu-lation of alloresponses. J Immunol 2002; 168: 1080.
-
(2002)
J Immunol
, vol.168
, pp. 1080
-
-
Kingsley, C.1
Karim, M.2
Bushell, A.3
-
19
-
-
3242801352
-
Large-scale in vitro expansion of polyclonal human CD4(+)CD25 high regulatory T cells
-
Hoffmann P, Eder R, Kunz-Schughart LA, et al. Large-scale in vitro expansion of polyclonal human CD4(+)CD25 high regulatory T cells. Blood2004; 104: 895.
-
(2004)
Blood
, vol.104
, pp. 895
-
-
Hoffmann, P.1
Eder, R.2
Kunz-Schughart, L.A.3
-
20
-
-
3142519564
-
In vitro-expanded human CD4( + )CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures
-
Godfrey WR, Ge YG, Spoden DJ, et al. In vitro-expanded human CD4( + )CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood 2004; 104: 453.
-
(2004)
Blood
, vol.104
, pp. 453
-
-
Godfrey, W.R.1
Ge, Y.G.2
Spoden, D.J.3
-
21
-
-
52049118092
-
Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation
-
Peters JH, Preijers FW, Woestenenk R, et al. Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation. PLoS One 2008; 3: e3161.
-
(2008)
PLoS One
, vol.3
-
-
Peters, J.H.1
Preijers, F.W.2
Woestenenk, R.3
-
22
-
-
0141678976
-
Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo
-
Jiang S, CamaraN, Lombardi G, et al. Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo. Blood 2003; 102:2180.
-
(2003)
Blood
, vol.102
, pp. 2180
-
-
Jiang, S.1
Camaran Lombardi, G.2
-
23
-
-
33746328653
-
Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity
-
Yamazaki S, Inaba K, Tarbell KV, et al. Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity. ImmunolRev 2006; 212: 314.
-
(2006)
ImmunolRev
, vol.212
, pp. 314
-
-
Yamazaki, S.1
Inaba, K.2
Tarbell, K.V.3
-
25
-
-
34248394243
-
Expansion of CD4+CD25 + suppressive regulatory T cells from rhesus macaque peripheral blood by FN18/antihuman CD28-coated Dynal beads
-
Gansuvd B, Asiedu CK, Goodwin J, et al. Expansion of CD4+CD25 + suppressive regulatory T cells from rhesus macaque peripheral blood by FN18/antihuman CD28-coated Dynal beads. Hum Immunol 2007; 68: 478.
-
(2007)
Hum Immunol
, vol.68
, pp. 478
-
-
Gansuvd, B.1
Asiedu, C.K.2
Goodwin, J.3
-
26
-
-
35748961135
-
Suppression of SIV-specific CD4 + T cells by infant but not adult macaque regulatory T cells: Implications for SIV disease progression
-
Hartigan-O'Connor DJ, Abel K, McCune JM. Suppression of SIV-specific CD4 + T cells by infant but not adult macaque regulatory T cells: Implications for SIV disease progression. J Exp Med 2007; 204:2679.
-
(2007)
J Exp Med
, vol.204
, pp. 2679
-
-
Hartigan-O'Connor, D.J.1
Abel, K.2
McCune, J.M.3
-
27
-
-
42549109116
-
Characterization of naturally occurring CD4+CD25+ regulatory T cells in rhesus monkeys
-
Haanstra KG, van der Maas MJ, Hart BA, et al. Characterization of naturally occurring CD4+CD25+ regulatory T cells in rhesus monkeys. Transplantation 2008; 85: 1185.
-
(2008)
Transplantation
, vol.85
, pp. 1185
-
-
Haanstra, K.G.1
Van Der Maas, M.J.2
Hart, B.A.3
-
28
-
-
43449136472
-
Superiority of bone marrow-derived dendritic cells over monocyte-derived ones for the expansion of regulatory T cells in the macaque
-
Moreau A, Chiffoleau E, Beriou G, et al. Superiority of bone marrow-derived dendritic cells over monocyte-derived ones for the expansion of regulatory T cells in the macaque. Transplantation 2008; 85: 1351.
-
(2008)
Transplantation
, vol.85
, pp. 1351
-
-
Moreau, A.1
Chiffoleau, E.2
Beriou, G.3
-
29
-
-
34547514184
-
Characterization and expansion of baboon CD4+CD25+ Treg cells for potential use in a non-human primate xenotransplantation model
-
Porter CM, Horvath-Arcidiacono JA, Singh AK, et al. Characterization and expansion of baboon CD4+CD25+ Treg cells for potential use in a non-human primate xenotransplantation model. Xenotransplantation 2007; 14: 298.
-
(2007)
Xenotransplantation
, vol.14
, pp. 298
-
-
Porter, C.M.1
Horvath-Arcidiacono, J.A.2
Singh, A.K.3
-
30
-
-
53749087931
-
Expanded nonhuman primate Tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses
-
Anderson A, Martens CL, Hendrix R, et al. Expanded nonhuman primate Tregs exhibit a unique gene expression signature and potently downregulate alloimmune responses. Am J Transplant 2008; 8: 2252.
-
(2008)
Am J Transplant
, vol.8
, pp. 2252
-
-
Anderson, A.1
Martens, C.L.2
Hendrix, R.3
-
31
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
-
Liu W, Putnam AL, Xu-Yu Z, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006; 203: 1701.
-
(2006)
J Exp Med
, vol.203
, pp. 1701
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
-
32
-
-
33745813929
-
Expression of interleu-kin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki N, Santner-Nanan B, Martinson J, et al. Expression of interleu-kin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006; 203: 1693.
-
(2006)
J Exp Med
, vol.203
, pp. 1693
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
-
33
-
-
34547627452
-
Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques
-
Zahorchak AF, Kean LS, Tokita D, et al. Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques. Transplantation 2007; 84: 196.
-
(2007)
Transplantation
, vol.84
, pp. 196
-
-
Zahorchak, A.F.1
Kean, L.S.2
Tokita, D.3
-
34
-
-
0034161714
-
1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
-
Penna G, Adorini L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 2000; 164: 2405.
-
(2000)
J Immunol
, vol.164
, pp. 2405
-
-
Penna, G.1
Adorini, L.2
-
35
-
-
0031573204
-
Induction of tolerance by IL-10-treated dendritic cells
-
Steinbrink K, Wolfl M, Jonuleit H, et al. Induction of tolerance by IL-10-treated dendritic cells. J Immunol 1997; 159: 4772.
-
(1997)
J Immunol
, vol.159
, pp. 4772
-
-
Steinbrink, K.1
Wolfl, M.2
Jonuleit, H.3
-
36
-
-
0345827684
-
Dendritic cells: Emerging pharmacological targets of immunosuppressive drugs
-
Hackstein H, Thomson AW. Dendritic cells: Emerging pharmacological targets of immunosuppressive drugs. Nat Rev Immunol 2004; 4: 24.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 24
-
-
Hackstein, H.1
Thomson, A.W.2
-
37
-
-
39449126502
-
The Foxp3+ regulatory T cell: A jack of all trades, master of regulation
-
Tang Q, Bluestone JA. The Foxp3+ regulatory T cell: A jack of all trades, master of regulation. Nat Immunol 2008; 9: 239.
-
(2008)
Nat Immunol
, vol.9
, pp. 239
-
-
Tang, Q.1
Bluestone, J.A.2
-
38
-
-
0034613767
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 2000; 192: 1213.
-
(2000)
J Exp Med
, vol.192
, pp. 1213
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
-
39
-
-
12844274909
-
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4 + Tr cells
-
Levings MK, Gregori S, Tresoldi E, et al. Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4 + Tr cells. Blood 2005; 105: 1162.
-
(2005)
Blood
, vol.105
, pp. 1162
-
-
Levings, M.K.1
Gregori, S.2
Tresoldi, E.3
-
40
-
-
0037302966
-
Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases
-
Adorini L, Penna G, Giarratana N, et al. Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases. JCellBiochem 2003; 88:227.
-
(2003)
JCellBiochem
, vol.88
, pp. 227
-
-
Adorini, L.1
Penna, G.2
Giarratana, N.3
-
41
-
-
1642403899
-
Modified dendritic cells coexpressing self and allogeneic major histocompatibility complex molecules: An efficient way to induce indirect pathway regulation
-
Mirenda V, Berton I, Read J, et al. Modified dendritic cells coexpressing self and allogeneic major histocompatibility complex molecules: An efficient way to induce indirect pathway regulation. J Am Soc Nephrol 2004; 15: 987.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 987
-
-
Mirenda, V.1
Berton, I.2
Read, J.3
-
42
-
-
0038036797
-
Rapamycin inhibits IL-4-Induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
-
Hackstein H, Taner T, Zahorchak AF, et al. Rapamycin inhibits IL-4-Induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood 2003; 101: 4457.
-
(2003)
Blood
, vol.101
, pp. 4457
-
-
Hackstein, H.1
Taner, T.2
Zahorchak, A.F.3
-
43
-
-
34547214205
-
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
-
Roncarolo MG, Battaglia M. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat Rev Immunol 2007; 7: 585.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 585
-
-
Roncarolo, M.G.1
Battaglia, M.2
-
44
-
-
65349119715
-
Induction of heart transplant tolerance by post-transplant administration of allo-Ag apecific Treg and rapamycin
-
abstract no. 266
-
Raimondi G, Sumpter TL, Matta B, et al. Induction of heart transplant tolerance by post-transplant administration of allo-Ag apecific Treg and rapamycin. Am J Transplant 2008; 8: 249 (abstract no. 266).
-
(2008)
Am J Transplant
, vol.8
, pp. 249
-
-
Raimondi, G.1
Sumpter, T.L.2
Matta, B.3
-
45
-
-
46949102513
-
Differential regulation of naive and memory CD4+ T cells by alternatively activated dendritic cells
-
Anderson AE, Sayers BL, Haniffa MA, et al. Differential regulation of naive and memory CD4+ T cells by alternatively activated dendritic cells. J Leukoc Biol 2008; 84: 124.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 124
-
-
Anderson, A.E.1
Sayers, B.L.2
Haniffa, M.A.3
|