TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116

Biochemical and Biophysical Research Communications

Volumn 391, Issue 1, 2010, Pages 449-454

  Choi, Jee Hye ^a   Min, Na Young ^a   Park, Jina ^a   Kim, Jin Hong ^a   Park, Soo Hyun ^a   Ko, Young Jong ^a   Kang, Yoonsung ^a,b   Moon, Young Joon ^a   Rhee, Sangmyung ^a   Ham, Seung Wook ^a   Park, Ae Ja ^a   Lee, Kwang Ho ^a  

^a Chung Ang University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

DNA methylation; DNA methyltransferase 1; Epigenetic regulation; Human telomerase reverse transcriptase; Trichostatin A

Indexed keywords

DNA METHYLTRANSFERASE 1; ENZYME INHIBITOR; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR CTCF; TRICHOSTATIN A;

APOPTOSIS; ARTICLE; BINDING SITE; CELL CYCLE ARREST; CHROMATIN IMMUNOPRECIPITATION; COLON CANCER; CONTROLLED STUDY; CPG ISLAND; DEMETHYLATION; DOWN REGULATION; EPIGENETICS; GENE CONTROL; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DOWN-REGULATION; EPIGENESIS, GENETIC; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; TELOMERASE;

EID: 72949088625     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.11.078     Document Type: Article

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