InsulinPI3K signaling protects dentate neurons from oxygen-glucose deprivation in organotypic slice cultures

Journal of Neurochemistry

Volumn 112, Issue 2, 2010, Pages 377-388

  Sun, Xiaolu ^a   Yao, Hang ^a   Douglas, Robert M ^a   Gu, Xiang Q ^a   Wang, Juan ^a   Haddad, Gabriel G ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RADY CHILDREN'S HOSPITAL   (United States)

Author keywords

Akt; Dentate gyrus; Insulin; Insulin like growth factor 1; Oxygen glucose deprivation; Phosphatidylinositol 3 kinase

Indexed keywords

3 (CARBOXYPIPERAZIN 4 YL)PROPYL 1 PHOSPHONIC ACID; GLUCOSE; GLUTAMIC ACID; INSULIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OXYGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIDIUM IODIDE; PROTEIN KINASE B; SOMATOMEDIN C; UNCLASSIFIED DRUG; 4',6 DIAMIDINO 2 PHENYLINDOLE; AMINO ACID RECEPTOR BLOCKING AGENT; DIAGNOSTIC AGENT; ENZYME INHIBITOR; INDOLE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN SLICE; CELL DAMAGE; CELL DISRUPTION; CELL FUNCTION; CELL INTERACTION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOARCHITECTURE; DENTATE GYRUS; DISEASE PREDISPOSITION; DISEASE RESISTANCE; DRUG MECHANISM; ENZYME INHIBITION; HIPPOCAMPUS; IN VITRO STUDY; MOUSE; NEUROANATOMY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TISSUE CULTURE; ANALYSIS OF VARIANCE; ANIMAL; ANOXIA; CELL DEATH; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; METABOLISM; NERVE CELL; NEWBORN; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGY; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANOXIA; CELL DEATH; DENTATE GYRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GLUCOSE; GLUTAMIC ACID; INDOLES; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MICE; NEURONS; ORGAN CULTURE TECHNIQUES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 72849132293     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06450.x     Document Type: Article

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