Novel regulation of HIV-1 replication and pathogenicity: Rev inhibition of integration

Protein Engineering, Design and Selection

Volumn 22, Issue 12, 2009, Pages 753-763

  Levin, Aviad ^a   Hayouka, Zvi ^b   Brack Werner, Ruth ^c   Volsky, David J ^d   Friedler, Assaf ^b   Loyter, Abraham ^a  

^a The Alexander Silberman Institute of Life Sciences   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cell death; HIV 1; Integrase; Integration regulation; Rev

Indexed keywords

HIV-1; HIV-1 INTEGRASE; HOST CELLS; HUMAN IMMUNODEFICIENCY VIRUS TYPE-1; INFECTED CELLS; INTEGRASE; MOLECULAR MECHANISM; NUMBER OF INTEGRATIONS; QUANTITATIVE ESTIMATION; REGULATORY FUNCTIONS; REVERSE TRANSCRIPTION; VIRAL INTEGRASE; VIRAL RNA;

AMINES; CELL CULTURE; CELL DEATH; LAWS AND LEGISLATION; NUCLEIC ACIDS; RNA; TRANSCRIPTION; VIRUSES;

INTEGRATION;

REV PROTEIN; VIRUS PROTEIN;

ARTICLE; CELL DEATH; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SPLICING; VIRUS REPLICATION; VIRUS VIRULENCE;

BASE SEQUENCE; CELL LINE; DNA PRIMERS; DNA, VIRAL; GENE PRODUCTS, REV; HIV-1; HUMANS; IMMUNOPRECIPITATION; POLYMERASE CHAIN REACTION; VIRUS INTEGRATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 72649102986     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzp060     Document Type: Article

References (39)

1. Bahner, I., Zhou, C., Yu, X.J., Hao, Q.L., Guatelli, J.C. and Kohn, D.B. (1993) J. Virol., 67, 3199-3207.
2. Butler, S.L., Hansen, M.S. and Bushman, F.D. (2001) Nat. Med., 7, 631-634.
3. Cara, A. and Klotman, M.E. (2006) J. Leukoc. Biol., 80, 1013-1017.
4. Casabianca, A., Gori, C., Orlandi, C., Forbici, F., Federico Perno, C. and Magnani, M. (2007) Mol. Cell. Probes, 21, 368-378.
5. Chen, A., Weber, I.T., Harrison, R.W. and Leis, J. (2006) J. Biol. Chem., 281, 4173-4182.
6. Chun, T.W. et al. (1997) Nature, 387, 183-188.
7. Cullen, B.R. (1987) Methods Enzymol., 152, 684-704.
8. Derdeyn, C.A., Decker, J.M., Sfakianos, J.N., Wu, X., O'Brien, W.A., Ratner, L., Kappes, J.C., Shaw, G.M. and Hunter, E. (2000) J. Virol., 74, 8358-8367.
9. Engelman, A., Mizuuchi, K. and Craigie, R. (1991) Cell, 67, 1211-1221.
10. Field, F.J., Born, E., Murthy, S. and Mathur, S.N. (2002) Biochem. J., 368, 855-864.
11. Freed, E.O. (2001) Somat. Cell Mol. Genet., 26, 13-33.
12. Freed, E.O. and Martin, M.A. (2001) In Howley, P.M. (ed.), Fields Virology, Vol.2. Lippincott Williams and Wilkins, Philadelphia, pp. 1971-2041.
13. Guiot, E., Carayon, K., Delelis, O., Simon, F., Tauc, P., Zubin, E., Gottikh, M., Mouscadet, J.F., Brochon, J.C. and Deprez, E. (2006) J. Biol. Chem., 281, 22707-22719.
14. Gummuluru, S., Kinsey, C.M. and Emerman, M. (2000) J. Virol., 74, 10882-10891.
15. Hayouka, Z., Rosenbluh, J., Levin, A., Maes, M., Loyter, A. and Friedler, A. (2008) Biopolymers, 90, 481-487.
16. Iyer, S.R., Yu, D., Biancotto, A., Margolis, L.B. and Wu, Y. (2009) J. Virol., 83, 8662-8673.
17. Jung, A., Maier, R., Vartanian, J.P., Bocharov, G., Jung, V., Fischer, U., Meese, E., Wain-Hobson, S. and Meyerhans, A. (2002) Nature, 418, 144.
18. Kelly, J., Beddall, M.H., Yu, D., Iyer, S.R., Marsh, J.W. and Wu, Y. (2008) Virology, 372, 300-312.
19. Kimpton, J. and Emerman, M. (1992) J. Virol., 66, 2232-2239.
20. Kohler, F., Cardon, G., Pohlman, M., Gill, R. and Schider, O. (1989) Plant Mol. Biol., 12, 189-199.
21. Kramer-Hammerle, S., Ceccherini-Silberstein, F., Bickel, C., Wolff, H., Vincendeau, M., Werner, T., Erfle, V. and Brack-Werner, R. (2005) BMC Cell Biol., 6, 20.
22. Levin, A., Kutznetova, L., Kahana, R., Rubinstein-Guini, M. and Stram, Y. (2006) Virus Res., 120, 121-127.
23. Levin, A., Hayouka, Z., Helfer, M., Brack-Werner, R., Friedler, A. and Loyter, A. (2009) PLoS One, 4, e 4155.
24. Maertens, G., Cherepanov, P., Pluymers, W., Busschots, K., De Clercq, E., Debyser, Z. and Engelborghs, Y. (2003) J. Biol. Chem., 278, 33528-33539.
25. Nakajima, N., Lu, R. and Engelman, A. (2001) J. Virol., 75, 7944-7955.
26. Pizzato, M., Erlwein, O., Bonsall, D., Kaye, S., Muir, D. and McClure, M.O. (2009) J. Virol. Methods, 156, 1-7.
27. Pollard, V.W. and Malim, M.H. (1998) Ann. Rev. Microbiol., 52, 491-532.
28. Pommier, Y., Johnson, A.A. and Marchand, C. (2005) Nat. Rev. Drug Discov., 4, 236-248.
29. Ratner, L. et al. (1985) Nature, 313, 277-284.
30. Reiser, J. (2000) Gene Ther., 7, 910-913.
31. Rosenbluh, J., Hayouka, Z., Loya, S., Levin, A., Armon-Omer, A., Britan, E., Hizi, A., Kotler, M., Friedler, A. and Loyter, A. (2007) J. Biol. Chem., 282, 15743-15753.
32. Tan, W., Dong, Z., Wilkinson, T.A., Barbas, C.F., III and Chow, S.A. (2006) J. Virol., 80, 1939-1948.
33. Verhoef, K., Koper, M. and Berkhout, B. (1997) Virology, 237, 228-236.
34. Wolff, H., Hadian, K., Ziegler, M., Weierich, C., Kramer-Hammerle, S., Kleinschmidt, A., Erfle, V. and Brack-Werner, R. (2006) Exp. Cell Res., 312, 443-456.
35. Wu, Y. (2004) Retrovirology, 1, 13.
36. Wu, Y. and Marsh, J.W. (2003a) J. Virol., 77, 10376-10382.
37. Wu, Y. and Marsh, J.W. (2003b) Microbes Infect., 5, 1023-1027.
38. Yamamoto, N., Tanaka, C., Wu, Y., Chang, M.O., Inagaki, Y., Saito, Y., Naito, T., Ogasawara, H., Sekigawa, I. and Hayashida, Y. (2006) Virus Genes, 32, 105-113.
39. Zhang, J., Scadden, D.T. and Crumpacker, C.S. (2007) J. Clin. Invest., 117, 473-481.