메뉴 건너뛰기




Volumn 83, Issue 17, 2009, Pages 8662-8673

Measurement of human immunodeficiency virus type 1 preintegration transcription by using Rev-dependent Rev-CEM cells reveals a sizable transcribing DNA population comparable to that from proviral templates

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; REV PROTEIN; TRANSACTIVATOR PROTEIN; VIRUS DNA; CIRCULAR DNA; MESSENGER RNA; VIRUS RNA;

EID: 69249219158     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00874-09     Document Type: Article
Times cited : (30)

References (66)
  • 1
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., H. E. Gendelman, S. Koenig, T. Folks, R. Willey, A. Rabson, and M. A. Martin. 1986. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:284-291. (Pubitemid 16013975)
    • (1986) Journal of Virology , vol.59 , Issue.2 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3
  • 2
    • 0028351327 scopus 로고
    • A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects
    • Aguilar-Cordova, E., J. Chinen, L. Donehower, D. E. Lewis, and J. W. Belmont. 1994. A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects. AIDS Res. Hum. Retrovir. 10:295-301.
    • (1994) AIDS Res. Hum. Retrovir. , vol.10 , pp. 295-301
    • Aguilar-Cordova, E.1    Chinen, J.2    Donehower, L.3    Lewis, D.E.4    Belmont, J.W.5
  • 3
    • 0030835321 scopus 로고    scopus 로고
    • Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for nef and the sensitivity to Cyclosporin a
    • Aiken, C. 1997. Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A. J. Virol. 71:5871-5877. (Pubitemid 27304923)
    • (1997) Journal of Virology , vol.71 , Issue.8 , pp. 5871-5877
    • Aiken, C.1
  • 4
    • 0032544559 scopus 로고    scopus 로고
    • Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat
    • Benkirane, M., R. F. Chun, H. Xiao, V. V. Ogryzko, B. H. Howard, Y. Nakatani, and K. T. Jeang. 1998. Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat. J. Biol. Chem. 273:24898-24905.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24898-24905
    • Benkirane, M.1    Chun, R.F.2    Xiao, H.3    Ogryzko, V.V.4    Howard, B.H.5    Nakatani, Y.6    Jeang, K.T.7
  • 5
    • 0023647997 scopus 로고
    • Correct integration of retroviral DNA in vitro
    • Brown, P. O., B. Bowerman, H. E. Varmus, and J. M. Bishop. 1987. Correct integration of retroviral DNA in vitro. Cell 49:347-356.
    • (1987) Cell , vol.49 , pp. 347-356
    • Brown, P.O.1    Bowerman, B.2    Varmus, H.E.3    Bishop, J.M.4
  • 6
    • 4644251528 scopus 로고    scopus 로고
    • Evidence for gene expression by unintegrated human immunodeficiency virus type 1 DNA species
    • DOI 10.1128/JVI.78.20.11263-11271.2004
    • Brussel, A., and P. Sonigo. 2004. Evidence for gene expression by uninte-grated human immunodeficiency virus type 1 DNA species. J. Virol. 78: 11263-11271. (Pubitemid 39299665)
    • (2004) Journal of Virology , vol.78 , Issue.20 , pp. 11263-11271
    • Brussel, A.1    Sonigo, P.2
  • 7
    • 0026054892 scopus 로고
    • Quiescent T lymphocytes as an inducible virus reservoir in HIV-1 infection
    • Bukrinsky, M. I., T. L. Stanwick, M. P. Dempsey, and M. Stevenson. 1991. Quiescent T lymphocytes as an inducible virus reservoir in HIV-1 infection. Science 254:423-427.
    • (1991) Science , vol.254 , pp. 423-427
    • Bukrinsky, M.I.1    Stanwick, T.L.2    Dempsey, M.P.3    Stevenson, M.4
  • 8
    • 0035025888 scopus 로고    scopus 로고
    • A quantitative assay for HIV DNA integration in vivo
    • Butler, S. L., M. S. Hansen, and F. D. Bushman. 2001. A quantitative assay for HIV DNA integration in vivo. Nat. Med. 7:631-634.
    • (2001) Nat. Med. , vol.7 , pp. 631-634
    • Butler, S.L.1    Hansen, M.S.2    Bushman, F.D.3
  • 10
    • 0026442236 scopus 로고
    • An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1
    • Collman, R., J. W. Balliet, S. A. Gregory, H. Friedman, D. L. Kolson, N. Nathanson, and A. Srinivasan. 1992. An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J. Virol. 66:7517-7521.
    • (1992) J. Virol. , vol.66 , pp. 7517-7521
    • Collman, R.1    Balliet, J.W.2    Gregory, S.A.3    Friedman, H.4    Kolson, D.L.5    Nathanson, N.6    Srinivasan, A.7
  • 11
    • 0026591789 scopus 로고
    • The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs
    • D'Agostino, D. M., B. K. Felber, J. E. Harrison, and G. N. Pavlakis. 1992. The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs. Mol. Cell. Biol. 12:1375-1386.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1375-1386
    • D'Agostino, D.M.1    Felber, B.K.2    Harrison, J.E.3    Pavlakis, G.N.4
  • 12
    • 0024390073 scopus 로고
    • Retrovirus vectors containing an internal attachment site: Evidence that circles are not intermediates to murine retrovirus integration
    • Ellis, J., and A. Bernstein. 1989. Retrovirus vectors containing an internal attachment site: evidence that circles are not intermediates to murine retrovirus integration. J. Virol. 63:2844-2846. (Pubitemid 19137566)
    • (1989) Journal of Virology , vol.63 , Issue.6 , pp. 2844-2846
    • Ellis, J.1    Bernstein, A.2
  • 13
    • 0028915128 scopus 로고
    • Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
    • Engelman, A., G. Englund, J. M. Orenstein, M. A. Martin, and R. Craigie. 1995. Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. J. Virol. 69:2729-2736.
    • (1995) J. Virol. , vol.69 , pp. 2729-2736
    • Engelman, A.1    Englund, G.2    Orenstein, J.M.3    Martin, M.A.4    Craigie, R.5
  • 14
    • 27144505682 scopus 로고    scopus 로고
    • Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement
    • Fenard, D., W. Yonemoto, C. de Noronha, M. Cavrois, S. A. Williams, and W. C. Greene. 2005. Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. J. Immunol. 175:6050-6057. (Pubitemid 41508091)
    • (2005) Journal of Immunology , vol.175 , Issue.9 , pp. 6050-6057
    • Fenard, D.1    Yonemoto, W.2    De Noronha, C.3    Cavrois, M.4    Williams, S.A.5    Greene, W.C.6
  • 15
    • 0026544416 scopus 로고
    • A mutation in the human immunodeficiency virus type 1 transmembrane glycoprotein gp41 dominantly interferes with fusion and infectivity
    • Freed, E. O., E. L. Delwart, G. L. Buchschacher, Jr., and A. T. Panganiban. 1992. A mutation in the human immunodeficiency virus type 1 transmembrane glycoprotein gp41 dominantly interferes with fusion and infectivity. Proc. Natl. Acad. Sci. USA 89:70-74.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 70-74
    • Freed, E.O.1    Delwart, E.L.2    Buchschacher Jr., G.L.3    Panganiban, A.T.4
  • 16
    • 0023508124 scopus 로고
    • Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus
    • Garcia, J. A., F. K. Wu, R. Mitsuyasu, and R. B. Gaynor. 1987. Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus. EMBO J. 6:3761-3770.
    • (1987) EMBO J. , vol.6 , pp. 3761-3770
    • Garcia, J.A.1    Wu, F.K.2    Mitsuyasu, R.3    Gaynor, R.B.4
  • 17
    • 0031926091 scopus 로고    scopus 로고
    • Mutations in the human immunodeficiency virus type 1 integrase D,D(35)E motif do not eliminate provirus formation
    • Gaur, M., and A. D. Leavitt. 1998. Mutations in the human immunodeficiency virus type 1 integrase D,D(35)E motif do not eliminate provirus formation. J. Virol. 72:4678-4685.
    • (1998) J. Virol. , vol.72 , pp. 4678-4685
    • Gaur, M.1    Leavitt, A.D.2
  • 23
    • 0025149054 scopus 로고
    • Mutational analysis of the human immunodeficiency virus type 1 Rev trans-activator: Essential residues near the amino terminus
    • Hope, T. J., D. McDonald, X. J. Huang, J. Low, and T. G. Parslow. 1990. Mutational analysis of the human immunodeficiency virus type 1 Rev trans-activator: essential residues near the amino terminus. J. Virol. 64:5360-5366.
    • (1990) J. Virol. , vol.64 , pp. 5360-5366
    • Hope, T.J.1    McDonald, D.2    Huang, X.J.3    Low, J.4    Parslow, T.G.5
  • 24
    • 0026089413 scopus 로고
    • Minimal Rev-response element for type 1 human immunodeficiency virus
    • Huang, X. J., T. J. Hope, B. L. Bond, D. McDonald, K. Grahl, and T. G. Parslow. 1991. Minimal Rev-response element for type 1 human immunodeficiency virus. J. Virol. 65:2131-2134.
    • (1991) J. Virol. , vol.65 , pp. 2131-2134
    • Huang, X.J.1    Hope, T.J.2    Bond, B.L.3    McDonald, D.4    Grahl, K.5    Parslow, T.G.6
  • 25
    • 0028290825 scopus 로고
    • Control of RNA initiation and elongation at the HIV-1 promoter
    • Jones, K. A., and B. M. Peterlin. 1994. Control of RNA initiation and elongation at the HIV-1 promoter. Annu. Rev. Biochem. 63:717-743.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 717-743
    • Jones, K.A.1    Peterlin, B.M.2
  • 26
    • 0035794637 scopus 로고    scopus 로고
    • The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
    • DOI 10.1093/emboj/20.7.1726
    • Jordan, A., P. Defechereux, and E. Verdin. 2001. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J. 20:1726-1738. (Pubitemid 32299409)
    • (2001) EMBO Journal , vol.20 , Issue.7 , pp. 1726-1738
    • Jordan, A.1    Defechereux, P.2    Verdin, E.3
  • 27
    • 0023513563 scopus 로고
    • Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product
    • Kao, S. Y., A. F. Calman, P. A. Luciw, and B. M. Peterlin. 1987. Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature 330:489-493.
    • (1987) Nature , vol.330 , pp. 489-493
    • Kao, S.Y.1    Calman, A.F.2    Luciw, P.A.3    Peterlin, B.M.4
  • 28
    • 39449110192 scopus 로고    scopus 로고
    • Human macrophages support persistent transcription from unintegrated HIV-1 DNA
    • Kelly, J., M. H. Beddall, D. Yu, S. R. Iyer, J. W. Marsh, and Y. Wu. 2008. Human macrophages support persistent transcription from unintegrated HIV-1 DNA. Virology 372:300-312.
    • (2008) Virology , vol.372 , pp. 300-312
    • Kelly, J.1    Beddall, M.H.2    Yu, D.3    Iyer, S.R.4    Marsh, J.W.5    Wu, Y.6
  • 29
    • 0026562720 scopus 로고
    • Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene
    • Kimpton, J., and M. Emerman. 1992. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene. J. Virol. 66: 2232-2239.
    • (1992) J. Virol. , vol.66 , pp. 2232-2239
    • Kimpton, J.1    Emerman, M.2
  • 30
    • 0021835658 scopus 로고
    • Insertion mutagenesis of embryonal carcinoma cells by retroviruses
    • King, W., M. D. Patel, L. I. Lobel, S. P. Goff, and M. C. Nguyen-Huu. 1985. Insertion mutagenesis of embryonal carcinoma cells by retroviruses. Science 228:554-558. (Pubitemid 15071400)
    • (1985) Science , vol.228 , Issue.4699 , pp. 554-558
    • King, W.1    Patel, M.D.2    Lobel, L.I.3
  • 31
    • 36849011656 scopus 로고    scopus 로고
    • Detection, characterization and regulation of antisense transcripts in HIV-1
    • DOI 10.1186/1742-4690-4-71
    • Landry, S., M. Halin, S. Lefort, B. Audet, C. Vaquero, J. M. Mesnard, and B. Barbeau. 2007. Detection, characterization and regulation of antisense transcripts in HIV-1. Retrovirology 4:71. (Pubitemid 350226890)
    • (2007) Retrovirology , vol.4 , pp. 71
    • Landry, S.1    Halin, M.2    Lefort, S.3    Audet, B.4    Vaquero, C.5    Mesnard, J.-M.6    Barbeau, B.7
  • 32
    • 0025212686 scopus 로고
    • Identification of a cis-acting element in human immunodeficiency virus type 2 (HIV-2) that is responsive to the HIV-1 rev and human T-cell leukemia virus types I and II rex proteins
    • Lewis, N., J. Williams, D. Rekosh, and M. L. Hammarskjold. 1990. Identification of a cis-acting element in human immunodeficiency virus type 2 (HIV-2) that is responsive to the HIV-1 rev and human T-cell leukemia virus types I and II rex proteins. J. Virol. 64:1690-1697. (Pubitemid 20104907)
    • (1990) Journal of Virology , vol.64 , Issue.4 , pp. 1690-1697
    • Lewis, N.1    Williams, J.2    Rekosh, D.3    Hammarskjold, M.-L.4
  • 34
    • 0024337080 scopus 로고
    • The palindromic LTR-LTR junction of Moloney murine leukemia virus is not an efficient substrate for proviral integration
    • Lobel, L. I., J. E. Murphy, and S. P. Goff. 1989. The palindromic LTR-LTR junction of Moloney murine leukemia virus is not an efficient substrate for proviral integration. J. Virol. 63:2629-2637.
    • (1989) J. Virol. , vol.63 , pp. 2629-2637
    • Lobel, L.I.1    Murphy, J.E.2    Goff, S.P.3
  • 35
    • 0032520144 scopus 로고    scopus 로고
    • Infectivity enhancement by HIV-1 Nef is dependent on the pathway of virus entry: Implications for HIV-based gene transfer systems
    • DOI 10.1006/viro.1997.8966
    • Luo, T., J. L. Douglas, R. L. Livingston, and J. V. Garcia. 1998. Infectivity enhancement by HIV-1 Nef is dependent on the pathway of virus entry: implications for HIV-based gene transfer systems. Virology 241:224-233. (Pubitemid 28384195)
    • (1998) Virology , vol.241 , Issue.2 , pp. 224-233
    • Luo, T.1    Douglas, J.L.2    Livingston, R.L.3    Garcia, J.V.4
  • 36
    • 0024518918 scopus 로고
    • The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
    • Malim, M. H., J. Hauber, S. Y. Le, J. V. Maizel, and B. R. Cullen. 1989. The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. Nature 338:254-257.
    • (1989) Nature , vol.338 , pp. 254-257
    • Malim, M.H.1    Hauber, J.2    Le, S.Y.3    Maizel, J.V.4    Cullen, B.R.5
  • 37
    • 0038228138 scopus 로고
    • HIV-1 gp120/160 expressing cells up-regulate HIV-1 LTR directed gene expression in a cell line transfected with HIV-1 LTR-reporter gene constructs
    • Merzouki, A., P. Patel, S. Cassol, M. Ennaji, P. Tailor, F. R. Turcotte, M. O'Shaughnessy, and M. Arella. 1995. HIV-1 gp120/160 expressing cells up-regulate HIV-1 LTR directed gene expression in a cell line transfected with HIV-1 LTR-reporter gene constructs. Cell. Mol. Biol. (Noisy-le-Grand) 41: 445-452.
    • (1995) Cell. Mol. Biol. (Noisy-le-Grand) , vol.41 , pp. 445-452
    • Merzouki, A.1    Patel, P.2    Cassol, S.3    Ennaji, M.4    Tailor, P.5    Turcotte, F.R.6    O'Shaughnessy, M.7    Arella, M.8
  • 38
    • 0023553078 scopus 로고
    • Simple, rapid, quantitative, syncytium-forming microassay for the detection of human immunodeficiency virus neutralizing antibody
    • Nara, P. L., W. C. Hatch, N. M. Dunlop, W. G. Robey, L. O. Arthur, M. A. Gonda, and P. J. Fischinger. 1987. Simple, rapid, quantitative, syncytium-forming microassay for the detection of human immunodeficiency virus neutralizing antibody. AIDS Res. Hum. Retrovir. 3:283-302.
    • (1987) AIDS Res. Hum. Retrovir. , vol.3 , pp. 283-302
    • Nara, P.L.1    Hatch, W.C.2    Dunlop, N.M.3    Robey, W.G.4    Arthur, L.O.5    Gonda, M.A.6    Fischinger, P.J.7
  • 40
    • 0036838605 scopus 로고    scopus 로고
    • A sensitive, quantitative assay for human immunodeficiency virus type 1 integration
    • DOI 10.1128/JVI.76.21.10942-10950.2002
    • O'Doherty, U., W. J. Swiggard, D. Jeyakumar, D. McGain, and M. H. Malim. 2002. A sensitive, quantitative assay for human immunodeficiency virus type 1 integration. J. Virol. 76:10942-10950. (Pubitemid 35176211)
    • (2002) Journal of Virology , vol.76 , Issue.21 , pp. 10942-10950
    • O'Doherty, U.1    Swiggard, W.J.2    Jeyakumar, D.3    McGain, D.4    Malim, M.H.5
  • 41
    • 0036892676 scopus 로고    scopus 로고
    • Differential requirements for activation of integrated and transiently transfected human T-cell leukemia virus type 1 long terminal repeat
    • DOI 10.1128/JVI.76.24.12564-12573.2002
    • Okada, M., and K. T. Jeang. 2002. Differential requirements for activation of integrated and transiently transfected human T-cell leukemia virus type 1 long terminal repeat. J. Virol. 76:12564-12573. (Pubitemid 35386942)
    • (2002) Journal of Virology , vol.76 , Issue.24 , pp. 12564-12573
    • Okada, M.1    Jeang, K.-T.2
  • 42
    • 0025008853 scopus 로고
    • High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients
    • DOI 10.1038/343085a0
    • Pang, S., Y. Koyanagi, S. Miles, C. Wiley, H. V. Vinters, and I. S. Chen. 1990. High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature 343:85-89. (Pubitemid 20036361)
    • (1990) Nature , vol.343 , Issue.6253 , pp. 85-89
    • Pang, S.1    Koyanagi, Y.2    Miles, S.3    Wiley, C.4    Vinsters, H.V.5    Chen, I.S.Y.6
  • 43
    • 0021255866 scopus 로고
    • Circles with two tandem LTRs are precursors to integrated retrovirus DNA
    • Panganiban, A. T., and H. M. Temin. 1984. Circles with two tandem LTRs are precursors to integrated retrovirus DNA. Cell 36:673-679.
    • (1984) Cell , vol.36 , pp. 673-679
    • Panganiban, A.T.1    Temin, H.M.2
  • 44
    • 0025052645 scopus 로고
    • Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells
    • Pauza, C. D., J. E. Galindo, and D. D. Richman. 1990. Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells. J. Exp. Med. 172: 1035-1042.
    • (1990) J. Exp. Med. , vol.172 , pp. 1035-1042
    • Pauza, C.D.1    Galindo, J.E.2    Richman, D.D.3
  • 46
    • 0030007416 scopus 로고    scopus 로고
    • Production and characterization of high-titer stocks of rev-defective HIV-1
    • Riggs, N. L., and J. C. Guatelli. 1996. Production and characterization of high-titer stocks of rev-defective HIV-1. Virology 217:602-606.
    • (1996) Virology , vol.217 , pp. 602-606
    • Riggs, N.L.1    Guatelli, J.C.2
  • 47
    • 0025039294 scopus 로고
    • Accumulation of human immunodeficiency virus type 1 DNA in T cells: Result of multiple infection events
    • Robinson, H. L., and D. M. Zinkus. 1990. Accumulation of human immunodeficiency virus type 1 DNA in T cells: results of multiple infection events. J. Virol. 64:4836-4841. (Pubitemid 20329803)
    • (1990) Journal of Virology , vol.64 , Issue.10 , pp. 4836-4841
    • Robinson, H.L.1    Zinkus, D.M.2
  • 48
    • 1542287499 scopus 로고    scopus 로고
    • Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: Analysis with class I integrase mutants
    • Saenz, D. T., N. Loewen, M. Peretz, T. Whitwam, R. Barraza, K. G. Howell, J. M. Holmes, M. Good, and E. M. Poeschla. 2004. Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants. J. Virol. 78:2906-2920.
    • (2004) J. Virol. , vol.78 , pp. 2906-2920
    • Saenz, D.T.1    Loewen, N.2    Peretz, M.3    Whitwam, T.4    Barraza, R.5    Howell, K.G.6    Holmes, J.M.7    Good, M.8    Poeschla, E.M.9
  • 49
    • 1142309492 scopus 로고    scopus 로고
    • Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment
    • Sastry, L., Y. Xu, R. Cooper, K. Pollok, and K. Cornetta. 2004. Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment. Hum. Gene Ther. 15:221-226.
    • (2004) Hum. Gene Ther. , vol.15 , pp. 221-226
    • Sastry, L.1    Xu, Y.2    Cooper, R.3    Pollok, K.4    Cornetta, K.5
  • 50
    • 0033529258 scopus 로고    scopus 로고
    • HIV-1 Nef increases T cell activation in a stimulus-dependent manner
    • Schrager, J. A., and J. W. Marsh. 1999. HIV-1 Nef increases T cell activation in a stimulus-dependent manner. Proc. Natl. Acad. Sci. USA 96:8167-8172.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8167-8172
    • Schrager, J.A.1    Marsh, J.W.2
  • 51
    • 0021717961 scopus 로고
    • Molecular characterization of human T-cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome
    • Shaw, G. M., B. H. Hahn, S. K. Arya, J. E. Groopman, R. C. Gallo, and F. Wong-Staal. 1984. Molecular characterization of human T-cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome. Science 226:1165-1171. (Pubitemid 15221732)
    • (1984) Science , vol.226 , Issue.4679 , pp. 1165-1171
    • Shaw, G.M.1    Hahn, B.H.2    Arya, S.K.3
  • 52
    • 0019304428 scopus 로고
    • Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: Implications for retrovirus integration
    • Shoemaker, C., S. Goff, E. Gilboa, M. Paskind, S. W. Mitra, and D. Baltimore. 1980. Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: implications for retrovirus integration. Proc. Natl. Acad. Sci. USA 77:3932-3936.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 3932-3936
    • Shoemaker, C.1    Goff, S.2    Gilboa, E.3    Paskind, M.4    Mitra, S.W.5    Baltimore, D.6
  • 53
    • 0025238945 scopus 로고
    • HIV-1 replication is controlled at the level of T cell activation and proviral integration
    • Stevenson, M., T. L. Stanwick, M. P. Dempsey, and C. A. Lamonica. 1990. HIV-1 replication is controlled at the level of T cell activation and proviral integration. EMBO J. 9:1551-1560. (Pubitemid 20137012)
    • (1990) EMBO Journal , vol.9 , Issue.5 , pp. 1551-1560
    • Stevenson, M.1    Stanwick, T.L.2    Dempsey, M.P.3    Lamonica, C.A.4
  • 54
    • 1842457823 scopus 로고    scopus 로고
    • Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions
    • Svarovskaia, E. S., R. Barr, X. Zhang, G. C. Pais, C. Marchand, Y. Pommier, T. R. Burke, Jr., and V. K. Pathak. 2004. Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions. J. Virol. 78:3210-3222.
    • (2004) J. Virol. , vol.78 , pp. 3210-3222
    • Svarovskaia, E.S.1    Barr, R.2    Zhang, X.3    Pais, G.C.4    Marchand, C.5    Pommier, Y.6    Burke Jr., T.R.7    Pathak, V.K.8
  • 55
    • 0030940427 scopus 로고    scopus 로고
    • Circular forms of unintegrated human immunodeficiency virus type 1 DNA and high levels of viral protein expression: Association with dementia and multinucleated giant cells in the brains of patients with AIDS
    • Teo, I., C. Veryard, H. Barnes, S. F. An, M. Jones, P. L. Lantos, P. Luthert, and S. Shaunak. 1997. Circular forms of unintegrated human immunodeficiency virus type 1 DNA and high levels of viral protein expression: association with dementia and multinucleated giant cells in the brains of patients with AIDS. J. Virol. 71:2928-2933. (Pubitemid 27119935)
    • (1997) Journal of Virology , vol.71 , Issue.4 , pp. 2928-2933
    • Teo, I.1    Veryard, C.2    Barnes, H.3    An, S.F.4    Jones, M.5    Lantos, P.L.6    Luthert, P.7    Shaunak, S.8
  • 56
  • 57
    • 56349129585 scopus 로고    scopus 로고
    • Conditionally replicating lentiviral-hybrid episomal vectors for suicide gene therapy
    • Vargas, J., Jr., M. E. Klotman, and A. Cara. 2008. Conditionally replicating lentiviral-hybrid episomal vectors for suicide gene therapy. Antivir. Res. 80:288-294.
    • (2008) Antivir. Res. , vol.80 , pp. 288-294
    • Vargas Jr., J.1    Klotman, M.E.2    Cara, A.3
  • 58
    • 0028924020 scopus 로고
    • Human immunodeficiency virus type 1 integrase: Effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
    • Wiskerchen, M., and M. A. Muesing. 1995. Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells. J. Virol. 69:376-386. (Pubitemid 24378815)
    • (1995) Journal of Virology , vol.69 , Issue.1 , pp. 376-386
    • Wiskerchen, M.1    Muesing, M.A.2
  • 59
    • 48549099096 scopus 로고    scopus 로고
    • The second chance story of HIV-1 DNA: Unintegrated? Not a problem!
    • Wu, Y. 2008. The second chance story of HIV-1 DNA: unintegrated? Not a problem! Retrovirology 5:61.
    • (2008) Retrovirology , vol.5 , pp. 61
    • Wu, Y.1
  • 60
    • 34447259569 scopus 로고    scopus 로고
    • Rev-dependent indicator T cell line
    • Wu, Y., M. H. Beddall, and J. W. Marsh. 2007. Rev-dependent indicator T cell line. Curr. HIV Res. 5:395-403.
    • (2007) Curr. HIV Res. , vol.5 , pp. 395-403
    • Wu, Y.1    Beddall, M.H.2    Marsh, J.W.3
  • 61
    • 33847186235 scopus 로고    scopus 로고
    • Rev-dependent lentiviral expression vector
    • Wu, Y., M. H. Beddall, and J. W. Marsh. 2007. Rev-dependent lentiviral expression vector. Retrovirology 4:12.
    • (2007) Retrovirology , vol.4 , pp. 12
    • Wu, Y.1    Beddall, M.H.2    Marsh, J.W.3
  • 62
    • 0141632798 scopus 로고    scopus 로고
    • Early transcription from nonintegrated DNA in human immunodeficiency virus infection
    • DOI 10.1128/JVI.77.19.10376-10382.2003
    • Wu, Y., and J. W. Marsh. 2003. Early transcription from nonintegrated DNA in human immunodeficiency virus infection. J. Virol. 77:10376-10382. (Pubitemid 37129681)
    • (2003) Journal of Virology , vol.77 , Issue.19 , pp. 10376-10382
    • Wu, Y.1    Marsh, J.W.2
  • 63
    • 0035943355 scopus 로고    scopus 로고
    • Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA
    • DOI 10.1126/science.1061548
    • Wu, Y., and J. W. Marsh. 2001. Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA. Science 293:1503-1506. (Pubitemid 32801554)
    • (2001) Science , vol.293 , Issue.5534 , pp. 1503-1506
    • Wu, Y.1    Marsh, J.W.2
  • 65
    • 0028095020 scopus 로고
    • A general method for the generation of high-titer, pantropic retroviral vectors: Highly efficient infection of primary hepatocytes
    • Yee, J. K., A. Miyanohara, P. LaPorte, K. Bouic, J. C. Burns, and T. Friedmann. 1994. A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes. Proc. Natl. Acad. Sci. USA 91:9564-9568.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9564-9568
    • Yee, J.K.1    Miyanohara, A.2    LaPorte, P.3    Bouic, K.4    Burns, J.C.5    Friedmann, T.6
  • 66
    • 44349164639 scopus 로고    scopus 로고
    • Selective killing of HIV-1-positive macrophages and T cells by the Rev-dependent lentivirus carrying anthrolysin O from Bacillus anthracis
    • Young, J., Z. Tang, Q. Yu, D. Yu, and Y. Wu. 2008. Selective killing of HIV-1-positive macrophages and T cells by the Rev-dependent lentivirus carrying anthrolysin O from Bacillus anthracis. Retrovirology 5:36.
    • (2008) Retrovirology , vol.5 , pp. 36
    • Young, J.1    Tang, Z.2    Yu, Q.3    Yu, D.4    Wu, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.