Effects of chronic treatment with a low dose of nicorandil on the function of the rat aorta during ageing

Clinical and Experimental Pharmacology and Physiology

Volumn 36, Issue 10, 2009, Pages 988-994

  Raveaud, Stéphanie ^a   Mezin, Paulette ^c   Lavanchy, Nicole ^b   Starcher, Barry ^d   Mecham, Robert P ^e   Verdetti, Jean ^a   Faury, Gilles ^a,f  

^a Laboratory of Vascular Physiopathologies: Cellular Interactions Signalling and Ageing   (France)

^b Domaine Universitaire   (France)

^c GRENOBLE UNIVERSITY HOSPITAL   (France)

^d UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f CEA GRENOBLE   (France)

Author keywords

Ageing; Arterial mechanics; Arteries; ATP dependent potassium channels; Cardiovascular system; Collagen; Elastic fibres; Elastin; Nicorandil; Vasoactivity

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; COLLAGEN; DESMOSINE; ELASTIN; GLIBENCLAMIDE; HYDROXYPROLINE; NICORANDIL; NITRIC OXIDE; NITRIC OXIDE DONOR; NORADRENALIN; PROTEIN;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA WALL; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART PROTECTION; HISTOLOGY; LONG TERM CARE; LOW DRUG DOSE; MYOGRAPHY; NONHUMAN; PROTEIN CONTENT; PROTEIN FUNCTION; RAT; SMOOTH MUSCLE RELAXATION; THORACIC AORTA; VASOCONSTRICTION; VASODILATATION;

AGING; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA; BIOMECHANICS; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION, PRECLINICAL; ELASTIN; FEMALE; NIACINAMIDE; NICORANDIL; RATS; RATS, WISTAR; TIME FACTORS; VASODILATION;

EID: 72449146324     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2009.05174.x     Document Type: Article

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