A novel pro-apoptotic function of RACK1: Suppression of Src activity in the intrinsic and Akt pathways

Oncogene

Volumn 28, Issue 50, 2009, Pages 4421-4433

  Mamidipudi, V ^a   Cartwright, C A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt cell survival pathway; Apoptosis; Intrinsic pathway; Mitochondrial cell death; RACK1; Src

Indexed keywords

BIM PROTEIN; CASPASE 3; CASPASE 9; CYTOCHROME C; GREEN FLUORESCENT PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; RECEPTOR FOR ACTIVATED C KINASE 1; STAUROSPORINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR SRC; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL STRAIN HEK293; CELL SURVIVAL; COLON CANCER; CONTROLLED STUDY; DNA CONTENT; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASES; CELL SURVIVAL; COLONIC NEOPLASMS; CYTOCHROMES C; G1 PHASE; GTP-BINDING PROTEINS; HT29 CELLS; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAUROSPORINE;

EID: 72449137085     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.293     Document Type: Article

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