메뉴 건너뛰기




Volumn 8, Issue 7, 1999, Pages 1253-1262

A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3'-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; COMPLEMENTARY DNA; CONTIG; RNA;

EID: 0032776138     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/8.7.1253     Document Type: Article
Times cited : (124)

References (37)
  • 1
    • 0026747761 scopus 로고
    • Purification, sequence and cellular localisation of a novel chromosomal protein that binds to methylated DNA
    • Lewis, J.D., Meehan, R.R., Henzel, W.J., Maurer-Fogy, I., Jeppesen, P., Klein, F. and Bird, A. (1992) Purification, sequence and cellular localisation of a novel chromosomal protein that binds to methylated DNA. Cell. 69, 905-914.
    • (1992) Cell. , vol.69 , pp. 905-914
    • Lewis, J.D.1    Meehan, R.R.2    Henzel, W.J.3    Maurer-Fogy, I.4    Jeppesen, P.5    Klein, F.6    Bird, A.7
  • 2
    • 0022540321 scopus 로고
    • CpG rich islands and the function of DNA methylation
    • Bird, A.P. (1986) CpG rich islands and the function of DNA methylation. Nature, 321, 209-213.
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 3
    • 0031149162 scopus 로고    scopus 로고
    • DNA methylation: A molecular lock
    • Siegfried, Z. and Cedar, H. (1997) DNA methylation: a molecular lock. Curr. Biol., 7, R305-R307.
    • (1997) Curr. Biol. , vol.7
    • Siegfried, Z.1    Cedar, H.2
  • 4
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacelylase complex
    • Nan, X., Ng, H.-H., Johnson, C.A., Laherty, C.D., Turner, B.M., Eisenman, R.N. and Bird, A. (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacelylase complex. Nature, 393, 386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.-H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 6
    • 0030071685 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 is essential for embryonic development in the mouse
    • Tate, P., Skarnes, W. and Bird, A. (1996) The methyl-CpG-binding protein MeCP2 is essential for embryonic development in the mouse. Nature Genet., 12, 205-208.
    • (1996) Nature Genet. , vol.12 , pp. 205-208
    • Tate, P.1    Skarnes, W.2    Bird, A.3
  • 7
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T.H. and Jaenisch, R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell, 69, 915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 8
    • 0028386510 scopus 로고
    • Identification of tissue-specific expressed sequences in human band Xq28 with complex pig cDNA probes
    • Coy, J.F, Kioschis, P., Sedlacek, Z. and Poustka, A. (1994) Identification of tissue-specific expressed sequences in human band Xq28 with complex pig cDNA probes. Mamm. Genome, 5, 131-137.
    • (1994) Mamm. Genome , vol.5 , pp. 131-137
    • Coy, J.F.1    Kioschis, P.2    Sedlacek, Z.3    Poustka, A.4
  • 9
    • 0029976005 scopus 로고    scopus 로고
    • Molecular cloning of tissue-specific transcripts of a transketolase related gene: Implications for the evolution of new vertebrate genes
    • Coy, J.F., Dübel, S., Kioschis, P., Thomas, K., Micklem, G., Delius, H. and Poustka, A. (1996) Molecular cloning of tissue-specific transcripts of a transketolase related gene: implications for the evolution of new vertebrate genes. Genomics, 32, 309-316.
    • (1996) Genomics , vol.32 , pp. 309-316
    • Coy, J.F.1    Dübel, S.2    Kioschis, P.3    Thomas, K.4    Micklem, G.5    Delius, H.6    Poustka, A.7
  • 10
    • 0029887459 scopus 로고    scopus 로고
    • Isolation, differential splicing and protein expression of a DNase on the human X chromosome
    • Coy, J.F., Velhagen, I., Himmele, R., Delius, H., Poustka, A. and Zentgraf, H. (1996) Isolation, differential splicing and protein expression of a DNase on the human X chromosome. Cell Death Differ., 3, 199-206.
    • (1996) Cell Death Differ. , vol.3 , pp. 199-206
    • Coy, J.F.1    Velhagen, I.2    Himmele, R.3    Delius, H.4    Poustka, A.5    Zentgraf, H.6
  • 11
    • 0030188404 scopus 로고    scopus 로고
    • Isolation, physical mapping and northern analysis of the X-linked human gene encoding methyl CpG-binding protein, MeCP2
    • D'Esposito, M., Quaderi, N.A., Ciccodicola, A., Bruni, P., Esposito, T., D'Urso, M. and Brown, S.D (1996) Isolation, physical mapping and northern analysis of the X-linked human gene encoding methyl CpG-binding protein, MeCP2. Mamm. Genome, 7, 533-535.
    • (1996) Mamm. Genome , vol.7 , pp. 533-535
    • D'Esposito, M.1    Quaderi, N.A.2    Ciccodicola, A.3    Bruni, P.4    Esposito, T.5    D'Urso, M.6    Brown, S.D.7
  • 12
    • 0029005521 scopus 로고
    • Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts
    • Decker, C.J. and Parker, R. (1995) Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts. Curr. Opin. Cell Biol., 7, 386-392.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 386-392
    • Decker, C.J.1    Parker, R.2
  • 15
    • 0029865142 scopus 로고    scopus 로고
    • IRAK: A kinase associated with the interleukin-1 receptor
    • Cao, Z., Henzel, W.J. and Gao, X. (1996) IRAK: a kinase associated with the interleukin-1 receptor. Science, 271, 1128-1131.
    • (1996) Science , vol.271 , pp. 1128-1131
    • Cao, Z.1    Henzel, W.J.2    Gao, X.3
  • 16
    • 0028762437 scopus 로고
    • The reference library system - Sharing biological material and experimental data
    • Zehetner, G. and Lehrach, H. (1994) The reference library system - sharing biological material and experimental data. Nature, 367, 489-491.
    • (1994) Nature , vol.367 , pp. 489-491
    • Zehetner, G.1    Lehrach, H.2
  • 17
    • 0025338173 scopus 로고
    • How the messenger got its tail: Addition of poly (A) in the nucleus
    • Wickens, M. (1990) How the messenger got its tail: addition of poly (A) in the nucleus. Trends Biochem. Sci., 15, 277-281.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 277-281
    • Wickens, M.1
  • 18
    • 0026100322 scopus 로고
    • Poly(A) signals
    • Proudfoot, N. (1991) Poly(A) signals. Cell, 64, 671-674.
    • (1991) Cell , vol.64 , pp. 671-674
    • Proudfoot, N.1
  • 19
    • 0028788194 scopus 로고
    • AU-rich elements: Characterisation and importance in mRNA degradation
    • Chen, C.-Y.A. and Shyu, A.-B. (1995) AU-rich elements: characterisation and importance in mRNA degradation. Trends Biochem. Sci., 20, 465-470.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 465-470
    • Chen, C.-Y.A.1    Shyu, A.-B.2
  • 20
    • 0019876473 scopus 로고
    • Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information
    • Zuker, M. and Stiegler, P. (1981) Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. Nucleic Acids Res., 9, 133-148.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 133-148
    • Zuker, M.1    Stiegler, P.2
  • 21
    • 0030789131 scopus 로고    scopus 로고
    • Alternative poly(A) site selection in complex transcription units: Means to an end?
    • Edwalds-Gilbert, G., Veraldi, K.L. and Milcarek, C. (1997) Alternative poly(A) site selection in complex transcription units: means to an end? Nucleic Acids Res., 25, 2547-2561.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2547-2561
    • Edwalds-Gilbert, G.1    Veraldi, K.L.2    Milcarek, C.3
  • 22
    • 0031859991 scopus 로고    scopus 로고
    • Alternate polyadenylation in human mRNAs: A large-scale analysis by EST clustering
    • Gautheret, D., Poirot, O., Lopez, F., Audic, S. and Claverie, J.-M. (1998) Alternate polyadenylation in human mRNAs: a large-scale analysis by EST clustering. Genome Res., 8, 524-530.
    • (1998) Genome Res. , vol.8 , pp. 524-530
    • Gautheret, D.1    Poirot, O.2    Lopez, F.3    Audic, S.4    Claverie, J.-M.5
  • 23
    • 0023853932 scopus 로고
    • Localisation and sequence analysis of poly(A) sites generating multiple dihydrofolate reductase mRNAs
    • Hook, A.G. and Kellems, R.E. (1988) Localisation and sequence analysis of poly(A) sites generating multiple dihydrofolate reductase mRNAs. J. Biol. Chem., 263, 2337-2343.
    • (1988) J. Biol. Chem. , vol.263 , pp. 2337-2343
    • Hook, A.G.1    Kellems, R.E.2
  • 24
    • 0030871226 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: Structural diversity of untranslated sequences suggest complex post-transcriptional regulation of ATM gene expression
    • Savitsky, K., Platzer, M., Uziel, T., Gilad, S., Sartiel, A., Rosenthal, A., Elroy-Stein, O., Shiloh, Y. and Rotman, G. (1997) Ataxia-telangiectasia: structural diversity of untranslated sequences suggest complex post-transcriptional regulation of ATM gene expression. Nucleic Acids Res., 25, 1678-1684.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1678-1684
    • Savitsky, K.1    Platzer, M.2    Uziel, T.3    Gilad, S.4    Sartiel, A.5    Rosenthal, A.6    Elroy-Stein, O.7    Shiloh, Y.8    Rotman, G.9
  • 25
    • 0025302185 scopus 로고
    • In the beginning is the end: Regulation of poly(A) addition and removal during early development
    • Wickens. M. (1990) In the beginning is the end: regulation of poly(A) addition and removal during early development. Trends Biochem. Sci., 15, 320-324.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 320-324
    • Wickens, M.1
  • 26
    • 0030743612 scopus 로고    scopus 로고
    • DNA methylation and imprinting: Why bother?
    • Jaenisch, R. (1997) DNA methylation and imprinting: why bother? Trends Genet., 13, 323-329.
    • (1997) Trends Genet. , vol.13 , pp. 323-329
    • Jaenisch, R.1
  • 27
    • 0030710153 scopus 로고    scopus 로고
    • How does DNA methylation repress transcription?
    • Kass, S.U., Pruss, D. and Wolffe, A.P. (1997) How does DNA methylation repress transcription? Trends Genet., 13, 444-449.
    • (1997) Trends Genet. , vol.13 , pp. 444-449
    • Kass, S.U.1    Pruss, D.2    Wolffe, A.P.3
  • 28
    • 0032483028 scopus 로고    scopus 로고
    • Evolutionary parameters of the transcribed mammalian genome: An analysis of 2820 orthologous rodent and human sequences
    • Makalowski, W. and Boguski, M.S. (1998) Evolutionary parameters of the transcribed mammalian genome: an analysis of 2820 orthologous rodent and human sequences. Proc. Natl Acad. Sci. USA, 95, 9407-9412.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 9407-9412
    • Makalowski, W.1    Boguski, M.S.2
  • 29
    • 0027280998 scopus 로고
    • Strong conservation of non-coding sequences during vertebrates evolution: Potential involvement in post-transcriptional regulation of gene expression
    • Duret, L., Dorkeld, F. and Gautier, C. (1993) Strong conservation of non-coding sequences during vertebrates evolution: potential involvement in post-transcriptional regulation of gene expression. Nucleic Acids Res., 21, 2315-2322.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2315-2322
    • Duret, L.1    Dorkeld, F.2    Gautier, C.3
  • 30
    • 0020793569 scopus 로고
    • A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity
    • Feinberg, A.P. and Vogelstein, B. (1983) A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132, 6.
    • (1983) Anal. Biochem. , vol.132 , pp. 6
    • Feinberg, A.P.1    Vogelstein, B.2
  • 32
    • 0023371227 scopus 로고
    • DNA sequence analysis with a modified bacteriophage T7 DNA polymerase
    • Tabor, S. and Richardson, C.C. (1987) DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Proc. Natl Acad. Sci. USA, 84, 4767.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 4767
    • Tabor, S.1    Richardson, C.C.2
  • 33
    • 0024234855 scopus 로고
    • CLUSTAL, a package for performing multiple sequence alignment on a microcomputer
    • Higgins, D.G. and Sharp, P.M. (1988) CLUSTAL, a package for performing multiple sequence alignment on a microcomputer. Gene. 73, 237-244.
    • (1988) Gene. , vol.73 , pp. 237-244
    • Higgins, D.G.1    Sharp, P.M.2
  • 34
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Devereux, J., Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res., 12, 387-395.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Devereux, J.1    Haeberli, P.2    Smithies, O.3
  • 35
    • 0023989064 scopus 로고
    • Improved tools for biological sequence comparison
    • Pearson, W.R. and Lipman, D.J. (1988) Improved tools for biological sequence comparison. Proc. Natl Acad. Sci. USA, 85, 2444-2448.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 2444-2448
    • Pearson, W.R.1    Lipman, D.J.2
  • 36
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 37
    • 0028914366 scopus 로고
    • Expression patterns of two human genes coding for different rat GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport
    • Bächner, D., Sedlacek, Z., Korn, B., Hameister, H. and Poustka, A. (1995) Expression patterns of two human genes coding for different rat GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport. Hum. Mol. Genet., 4, 701-708.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 701-708
    • Bächner, D.1    Sedlacek, Z.2    Korn, B.3    Hameister, H.4    Poustka, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.