Probes for narcotic receptor mediated phenomena. 40. N-Substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 1, 2010, Pages 91-99

  Iyer, Malliga R ^a   Lee, Yong Sok ^b   Deschamps, Jeffrey R ^c   Rothman, Richard B ^d   Dersch, Christina M ^d   Jacobson, Arthur E ^a   Rice, Kenner C ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NAVAL RESEARCH LABORATORY   (United States)

^d NIDA Addiction Research Center   (United States)

Author keywords

Geometry optimization; N substituted cis 4a ethyl 1,2,3,4,4a,9a hexahydrobenzofuro 2,3 c pyridin 8 ols; Opioid receptor binding; Oxide bridged phenylmorphans; Superposition; Synthesis

Indexed keywords

2 (CYCLOPROPYLMETHYL) 4A ETHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO [2,3 C]PYRIDIN 8 OL; 2 METHYL 4A PHENETHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO [2,3 C]PYRIDIN 8 OL; 4A ETHYL 2 (4 FLUOROBENZYL) 1,2,3,4,4A,9A HEXAHYDROBENZOFURO [2,3 C]PYRIDIN 8 OL; 4A ETHYL 2 (4 FLUOROPHENETHYL) 1,2,3,4,4A,9A HEXAHYDROBENZOFURO [2,3 C]PYRIDIN 8 OL; 4A ETHYL 2 (4 NITROPHENETHYL) 1,2,3,4,4A,9A HEXAHYDROBENZOFURO [2,3 C]PYRIDIN 8 OL; 4A ETHYL 2 METHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO [2,3 C]PYRIDIN 8 OL; 4A ETHYL 2 PHENETHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO [2,3 C]PYRIDIN 8 OL; ANTINOCICEPTIVE AGENT; OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR BINDING; X RAY CRYSTALLOGRAPHY;

ANIMALS; BENZOFURANS; CHO CELLS; CRICETINAE; CRICETULUS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; PYRIDINES; RECEPTORS, OPIOID;

EID: 72149134651     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.11.022     Document Type: Article

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