Probes for narcotic receptor mediated phenomena. 39. Enantiomeric n-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans

Journal of Medicinal Chemistry

Volumn 52, Issue 23, 2009, Pages 7570-7579

  Zhang, Yi ^a   Lee, Yong Sok ^a   Rothman, Richard B ^a   Dersch, Christina M ^a   Deschamps, Jeffrey R ^b   Jacobson, Arthur E ^a   Rice, Kenner C ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NAVAL RESEARCH LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2' HYDROXY 2 PHENYLETHYL) 4A ETHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO[2,3 C]PYRIDIN 6 OL; 2 (2' HYDROXY 2' PHENYLETHYL) 4A ETHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO[2,3 C]PYRIDIN 6 OL; 4A ETHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO[2,3 C]PYRIDIN 6 OL; 4A ETHYL 2 (2 PHENYLETHYL) 1,2,3,4,4A,9A HEXAHYDROBENZOFURO[2,3 C]PYRIDIN 6 OL; 4A ETHYL 2 METHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO[2,3 C]PYRIDIN 6 OL; 4A ETHYL 2 PHENYLETHYL 1,2,3,4,4A,9A HEXAHYDROBENZOFURO[2,3 C]PYRIDIN 6 OL; BENZOFURAN DERIVATIVE; MORPHINE; MORPHINE DERIVATIVE; OPIATE AGONIST; OPIATE RECEPTOR; OXIDE; PHENYLMORPHAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG BINDING; DRUG CONFORMATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; FEMALE; MOLECULAR PROBE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MORPHINANS; NITROGEN; OXIDES; PYRIDINES; QUANTUM THEORY; RECEPTORS, OPIOID; STEREOISOMERISM;

EID: 72249108558     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9004225     Document Type: Article

References (23)

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