Discriminative stimulus effects of L-838,417 (7-tert-butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-yl methoxy)-[1,2,4]triazolo[4,3-b]pyridazine): Role of GABAA receptor subtypes

Neuropharmacology

Volumn 58, Issue 2, 2010, Pages 357-364

  Licata, Stephanie C ^a   Platt, Donna M ^a   Rüedi Bettschen, Daniela ^a   Atack, John R ^b   Dawson, Gerard R ^b   Van Linn, Michael L ^c   Cook, James M ^c   Rowlett, James K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^c UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

Benzodiazepine; Discriminative stimulus; GABAA receptor; L 838,417; Squirrel monkey; Subjective effects

Indexed keywords

3 METHYL 6 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 TRIAZOLO[4,3 B]PYRIDAZINE; 4 AMINOBUTYRIC ACID A RECEPTOR; 7 TERT BUTYL 3 (2,5 DIFLUOROPHENYL) 6 (2 METHYL 2H 1,2,4 TRIAZOL 3 YLMETHOXY) 1,2,4 TRIAZOLO[4,3 B]PYRIDAZINE; ALCOHOL; AMOBARBITAL; BARBITURIC ACID DERIVATIVE; BETA CARBOLINE 3 CARBOXYLIC ACID BUTYL ESTER; BRETAZENIL; CHLORDIAZEPOXIDE; DIAZEPAM; FLUMAZENIL; MIDAZOLAM; MORPHINE; MUSCIMOL; PENTOBARBITAL; RECEPTOR SUBTYPE; SODIUM CHLORIDE; ZALEPLON; ZOLPIDEM;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR UPREGULATION; REINFORCEMENT; SQUIRREL MONKEY; STIMULUS RESPONSE;

ANIMALS; BARBITURATES; CARBOLINES; CATHETERIZATION; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DIAZEPAM; DISCRIMINATION (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FLUMAZENIL; FLUOROBENZENES; GABA AGONISTS; GABA ANTAGONISTS; GABA MODULATORS; NEUROPSYCHOLOGICAL TESTS; PYRIDINES; RECEPTORS, GABA-A; SAIMIRI; TRIAZOLES;

EID: 72149132029     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2009.10.004     Document Type: Article

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