Cobalt toxicity: Chemical and radiological combined effects on HaCaT keratinocyte cell line

Toxicology in Vitro

Volumn 24, Issue 1, 2010, Pages 92-98

  Gault, N ^a   Sandre, C ^b   Poncy, J L ^c   Moulin, C ^b   Lefaix, J L ^d   Bresson, C ^b  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b DIF   (France)

^c CEA DIF   (France)

^d INSTITUT DE RADIOBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

Author keywords

Additive effects; Cobalt; Combined chemical and radiochemical toxicity; DNA damage; HaCaT

Indexed keywords

COBALT; COBALT 60; COBALT CHLORIDE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL VIABILITY; CLONOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; GAMMA RADIATION; HUMAN; HUMAN CELL; KERATINOCYTE; OXIDATIVE STRESS; RADIATION EXPOSURE;

CELL LINE; CELL SURVIVAL; CLONE CELLS; COBALT; COBALT RADIOISOTOPES; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; HUMANS; KERATINOCYTES; REACTIVE OXYGEN SPECIES; RISK ASSESSMENT; SKIN;

EID: 72149121302     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.08.027     Document Type: Article

References (50)

1. Anard D., Kirsch-Volders M., Elhajouji A., Belpaeme K., and Lison D. In vitro genotoxic effects of hard metal particles assessed by alkaline single cell gel and elution assays. Carcinogenesis 18 (1997) 177-184
2. Asmuss M., Mullenders L.H., Eker A., and Hartwig A. Differential effects of toxic metal compounds on the activities of Fpg and XPA, two zinc finger proteins involved in DNA repair. Carcinogenesis 21 (2000) 2097-2104
3. Baldwin E.L., Byl J.A., and Osheroff N. Cobalt enhances DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells. Biochemistry 43 (2004) 728-735
4. Barceloux D.G. Cobalt. Journal of Toxicology. Clinical Toxicology 37 (1999) 201-206
5. Borenfreund E., and Puerner J.A. A simple quantitative procedure using monolayer cultures for cytotoxicity assays. Journal of Tissue Culture Methods 9 (1984) 7-9
6. Bresson C., Lamouroux C., Sandre C., Tabarant M., Gault N., Poncy J.L., Lefaix J.L., Den Auwer C., Spezia R., Gaigeot M.P., Ansoborlo E., Mounicou S., Fraysse A., Deves G., Bacquart T., Seznec H., Pouthier T., Moretto P., Ortega R., Lobinski R., and Moulin C. An interdisciplinary approach to investigate the impact of cobalt in a human keratinocyte cell line. Biochimie (2006) 1619-1629
7. Burgaz S., Demircigil G.C., Yilmazer M., Ertaş N., Kemaloglu Y., and Burgaz Y. Assessment of cytogenetic damage in lymphocytes and in exfoliated nasal cells of dental laboratory technicians exposed to chromium, cobalt, and nickel. Mutation Research 521 (2002) 47-56
8. Burkart W., and Ogorek B. Genotoxic action of cadmium and mercury in cell cultures and modulation of radiation effects. Toxicology and Environmental Chemistry 12 (1986) 173-183
9. Cadet J., Berger M., Douki T., and Ravanat J.L. Oxidative damage to DNA: formation, measurement, and biological significance. Reviews of Physiology, Biochemistry and Pharmacology 131 (1997) 1-87 (Review)
10. 60CO. Health Physics 92 (2007) 332-344
11. De Boeck M., Lison D., and Kirsch-Volders M. Evaluation of the in vitro direct and indirect genotoxic effects of cobalt compounds using the alkaline comet assay. Influence of inter donor and inter experimental variability. Carcinogenesis 19 (1998) 2021-2029
12. De Boeck M., Kirsch-Volders M., and Lison D. Cobalt and antimony: genotoxicity and carcinogenicity. Mutation Research 533 (2003) 135-152
13. Ermolli M., Menné C., Pozzi G., Serra M.A., and Clerici L.A. Nickel, cobalt and chromium-induced cytotoxicity and intracellular accumulation in human hacat keratinocytes. Toxicology 159 (2001) 23-31
14. Fotakis G., Cemeli E., Anderson D., and Timbrell J.A. Cadmium chloride-induced DNA and lysosomal damage in a hepatoma cell line. Toxicology In Vitro 19 (2005) 481-489
15. Gault N., Poncy J.L., and Lefaix J.L. Radiation-induced apoptosis: a new approach using infrared microspectroscopy. Canadian Journal of Physiology and Pharmacology 82 (2004) 38-49
16. 2-treated human cells. International Journal of Radiation Biology 81 (2005) 767-779
17. Hall E.J., and Brenner D.J. The dose-rate effect revisited: radiobiological considerations of importance in radiotherapy. International Journal of Radiation Oncology Biology Physics 21 (1991) 1403-1414
18. Hartwig A., Snyder R.D., Schlepegrell R., and Beyersmann D. Modulation by Co(II) of UV-induced DNA repair, mutagenesis and sister-chromatid exchanges in mammalian cells. Mutation Research 248 (1991) 177-185
19. Hartwig A., Asmuss M., Ehleben I., Herzer U., Kostelac D., Pelzer A., Schwerdtle T., and Bürkle A. Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms. Environmental Health Perspectives 110 (2002) 797-799
20. Hengstler J.G., Bolm-Audorff U., Faldum A., et al. Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected. Carcinogenesis 24 (2003) 63-73
21. Henseleit U., Rosenbach T., and Kolde G. Induction of apoptosis in human HaCaT keratinocytes. Archives of Dermatological Research 288 (1996) 676-683
22. Hininger I., Benaraba R., Osman M., Faure H., Marie Roussel A., and Anderson R.A. Safety of trivalent chromium complexes: no evidence for DNA damage in human HaCaT keratinocytes. Free Radical Biology and Medicine 42 (2007) 1759-1765
23. Hornhardt S., Gomolka M., Walsh L., and Jung T. Comparative investigations of sodium arsenite, arsenic trioxide and cadmium sulphate in combination with gamma-radiation on apoptosis, micronuclei induction and DNA damage in a human lymphoblastoid cell line. Mutation Research 600 (2006) 165-176
24. IARC, 2006. Monographs on the Evaluation of Carcinogenic Risks to Humans, Cobalt in Hard-metals and Cobalt Sulfate, Gallium Arsenide, Indium Phosphide and Vanadium Pentoxide, vol. 86. International Agency for Research on Cancer, Lyon, France.
25. 2-induced apoptosis. Brain Research Bulletin 76 (2008) 579-585
26. Kasten U., Mullenders L.H., and Hartwig A. Cobalt(II) inhibits the incision and the polymerization step of nucleotide excision repair in human fibroblasts. Mutation Research 383 (1997) 81-89
27. 60Co source. Health Physics 51 (1986) 601-607
28. Kopera E., Schwerdtle T., Hartwig A., and Bal W. Co(II) and Cd(II) substitute for Zn(II) in the zinc finger derived from the DNA repair protein XPA, demonstrating a variety of potential mechanisms of toxicity. Chemical Research in Toxicology 17 (2004) 1452-1458
29. Kusaka Y., Iki M., Kumagai S., and Goto S. Epidemiological study of hard metal asthma. Occupational and Environmental Medicine 53 (1996) 188-193
30. Lankoff A., Banasik A., Duma A., Ochniak E., Lisowska H., Kuszewski T., Góźdź S., and Wojcik A. A comet assay study reveals that aluminium induces DNA damage and inhibits the repair of radiation-induced lesions in human peripheral blood lymphocytes. Toxicology Letters 161 (2006) 27-36
31. Lauwerys R., and Lison D. Health risks associated with cobalt exposure - an overview. Science of the Total Environment 150 (1994) 1-6
32. Le Guen, B., Ansoborlo, E., 2005. Le cobalt et ses isotopes. Traité EMC. Elsevier SAS, Paris, 16-002-C-60.
33. Linna A., Oksa P., Palmroos P., Roto P., Laippala P., and Uitti J. Respiratory health of cobalt production workers. American Journal of Industrial Medicine 44 (2003) 124-132
34. Lison D., De Boeck M., Verougstraete V., and Kirsch-Volders M. Update on the genotoxicity and carcinogenicity of cobalt compounds. Occupational and Environmental Medicine 58 (2001) 619-625
35. Nackerdien Z., Kasprzak K.S., Rao G., Halliwell B., and Dizdaroglu M. Nickel(II)- and cobalt(II)-dependent damage by hydrogen peroxide to the DNA bases in isolated human chromatin. Cancer Research 51 (1991) 5837-5842
36. Nzengue Y., Steiman R., Garrel C., Lefèbvre E., and Guiraud P. Oxidative stress and DNA damage induced by cadmium in the human keratinocyte HaCaT cell line: role of glutathione in the resistance to cadmium. Toxicology 243 (2008) 193-206
37. Olive P.L. DNA damage and repair in individual cells: applications of the comet assay in radiobiology. International Journal of Radiation Biology 75 (1999) 395-405 (Review)
38. Petit-Frère C., Capulas E., Lyon D.A., Norbury C.J., Lowe J.E., Clingen P.H., Riballo E., Green M.H., and Arlett C.F. Apoptosis and cytokine release induced by ionizing or ultraviolet B radiation in primary and immortalized human keratinocytes. Carcinogenesis 21 (2000) 1087-1095
39. Pouget J.P., and Mather S.J. General aspects of the cellular response to low- and high-LET radiation. European Journal of Nuclear Medicine 28 (2001) 541-561 (Review)
40. Robison S.H., Cantoni O., and Costa M. Strand breakage and decreased molecular weight of DNA induced by specific metal compounds. Carcinogenesis 3 (1982) 657-662
41. Salnikow K., An W.G., Melillo G., Blagosklonny M.V., and Costa M. Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors. Carcinogenesis 20 (1999) 1819-1823
42. 2) in rats. Laboratory Animals 11 (1977) 43-46
43. Singh N.P., McCoy MT., Tice R.R., and Schreider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Experimental Cell Research 175 (1988) 184-191
44. Stavem P., Brogger A., Devik F., Flatby J., Vanderhagen C.B., Henriksen T., Hoel P.S., Host H., Kett K., and Petersen B. Acta Radiologica Oncology 24 (1985) 61-63
45. Van Goethem F., Lison D., and Kirsch-Volders M. Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide. Mutation Research 392 (1997) 31-43
46. Vengellur A., and LaPres J.J. The role of hypoxia inducible factor 1 alpha in cobalt chloride induced cell death in mouse embryonic fibroblasts. Toxicological Sciences 82 (2004) 638-646
47. Wang P., Guliaev A.B., and Hang B. Metal inhibition of human N-methylpurine-DNA glycosylase activity in base excision repair. Toxicology Letters 166 (2006) 237-247
48. 2-induced apoptosis. Toxicology In Vitro 23 (2009) 1069-1075
49. Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Progress in Nucleic Acid Research and Molecular Biology 35 (1988) 95-125 (Review)
50. Wild P., Perdrix A., Romanizi S., Moulin J.J., and Pellet F. Lung cancer mortality in a site producing hard metals. Occupational and Environmental Medicine 57 (2000) 568-573