Toxicogenomics of non-viral vectors for gene therapy: A microarray study of lipofectin- and oligofectamine-induced gene expression changes in human epithelial cells

Journal of Drug Targeting

Volumn 11, Issue 6, 2003, Pages 311-323

  Omidi, Yadollah ^a   Hollins, Andrew J ^a   Benboubetra, Mustapha ^a   Drayton, Ross ^a   Benter, Ibrahim F ^b   Akhtari, Saghir ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Antisense; Cationic lipids; Gene delivery; Gene expression profiling; Gene silencing; siRNA

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; DRUG CARRIER; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; LIPOFECTIN; OLIGOFECTAMINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CULTURE; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; DNA HYBRIDIZATION; DNA MICROARRAY; EPITHELIUM CELL; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; GENETIC COMPATIBILITY; GENETIC TOXICOLOGY; GENOTYPE; HUMAN; HUMAN CELL; NONVIRAL GENE THERAPY; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; TARGET CELL;

ANNEXIN A5; APOPTOSIS; CELLS, CULTURED; COMET ASSAY; DNA, COMPLEMENTARY; EPITHELIAL CELLS; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE THERAPY; GENETIC VECTORS; HUMANS; IN SITU HYBRIDIZATION; LIPIDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHATIDYLETHANOLAMINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 0347756922     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860310001636908     Document Type: Article

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