Gastroretentive drug delivery systems: Current developments in novel system design and evaluation

Current Drug Delivery

Volumn 6, Issue 5, 2009, Pages 451-460

  Murphy, Caragh S ^a   Pillay, Viness ^a   Choonara, Yahya E ^a   Du Toit, Lisa C ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Bioavailability; Biocompatible polymers; Buoyancy; Drug delivery; Effervescent; Expanding; Gastric retention; High density; Mucoadhesion; Multi units

Indexed keywords

ACICLOVIR; ALGINIC ACID; BARIUM SULFATE; BICARBONATE; CALCIUM ALGINATE; CAPTOPRIL; CELLACEFATE; CHITOSAN; CIPROFLOXACIN; CITRIC ACID; CROSCARMELLOSE SODIUM; ETHYL CELLULOSE; EUDRAGIT; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; IRON; LEVODOPA; MACROGOL; METFORMIN; METOCLOPRAMIDE; NITROFURANTOIN; POLYPROPYLENE; PROPANTHELINE BROMIDE; TARTARIC ACID; TITANIUM DIOXIDE; ZINC OXIDE;

DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG RELEASE; DRUG RETENTION; DRUG SCREENING; EFFERVESCENT TABLET; GAMMA SCINTIGRAPHY; GASTROINTESTINAL TRANSIT; HUMAN; HYDROGEL; ISOTOPE LABELING; MAGNET; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; STOMACH; STOMACH EMPTYING; STOMACH JUICE;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; GASTRIC EMPTYING; HUMANS; PHARMACEUTIC AIDS; PHARMACOKINETICS; STOMACH;

EID: 72149083842     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720109789941687     Document Type: Review

References (40)

1. Bardonnet, P.L.; Faivre, V.; Pugh, W.J.; Piffaretti, J.C.; Falson, F. Gastroretentive dosage forms: Overview and special case of Helicobacter pylori. J. Control. Release, 2006, 111, 1-18. (Pubitemid 43289989)
2. Davis, S.S. Formulation strategies for absorption windows. Drug Deliv. Today, 2005, 10, 249-257.
3. Sungthongjeen, S.; Sriamornsak, P.; Puttipipatkhachorn, S. Design and evaluation of floating multi-layer coated tablets based on gas formation. Eur. J. Pharm. Biopharm., 2008, 69, 255-263.
4. Fukuda, M.; Peppas, N.A.; McGinity, J.W. Floating hot-melt extruded tablets for gastroretentive controlled drug release system. J. Control. Release, 2006, 115, 121-129.
5. Ahmed, I.S.; Ayres, J.W. Bioavailability of riboflavin from a gastric retentive formulation. Int. J. Pharm., 2007, 330, 146-154.
6. Liu, Q.; Fassihi, R. Zero-order delivery of a highly soluble, low dose drug alfuzosin hydrochloride via gastro-retentive system. Int. J. Pharm., 2008, 348, 27-34. (Pubitemid 350278551)
7. Talukder, R.; Fassihi, R. Gastroretentive delivery systems: A mini review. Drug Dev. Indus. Pharm., 2004, 30, 1019-1028. (Pubitemid 39577994)
8. Streubel, A.; Siepmann J.; Bodmeier, R. Drug delivery to the upper small intestine window using gastroretentive technologies. Curr. Opin. Pharmacol., 2006, 6, 501-508. (Pubitemid 44340666)
9. Ishak, R.A.H.; Awad, G.A.S.; Mortada, N.D.; Nour, S.A.K. Preparation, in vitro and in vivo evaluation of stomach-specific metronidazole-loaded alginate beads as local anti-Helicobacter pylori therapy. J. Control. Release, 2007, 119, 207-214.
10. Goole, J.; Vanderbist, F.; Amighi, K. Development and evaluation of new multiple-unit levodopa sustained-release floating dosage forms. Int. J. Pharm., 2007, 334, 35-41.
11. Jain, S.K.; Awasthi, A.M.; Jain, N.K.; Agrawal, G.P. Calcium silicate based microspheres of repaglinide for gastroretentive floating drug delivery: Preparation and vitro characterization. J. Control. Release, 2005, 107, 300-309.
12. Smart, J.D. The basics and underlying mechanisms of mucoadhesion. Adv. Drug Deliv. Rev., 2005, 57, 1556-1568.
13. Thongborisute, J.; Takeuchi, H. Evaluation of mucoadhesiveness of polymers by BIACORE method and mucin-particle method. Int. J. Pharm., 2008, 354, 204-209.
14. Jamzad, S.; Fassihi, R. Development of a controlled release low dose class II drug-Glipizide. Int. J. Pharm., 2006, 312, 24-32.
15. Sher, P.; Ingavle, G.; Ponratnam, S.; Pawar, A. Low density porous carrier: Drug adsorption and release by response surface methodology using different solvents. Int. J. Pharm., 2007, 331, 72-83. (Pubitemid 46176502)
16. Crowley, M.M.; Schroeder, B.; Fredersdorf, A.; Obara, S.; Talarico, M.; Kucera, S.; McGinity, J.W. Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion. Int. J. Pharm., 2004, 269, 509-522.
17. Moustafine, R.I.; Kabanova, T.V.; Kemenova, V.A.; Van den Mooter, G. Characteristics of interpolyelectrolyte complexes of Eudragit E100 with Eudragit L100. J. Control. Release, 2005, 103, 191-198. (Pubitemid 40248571)
18. Arora, S.; Ali, J.; Ahuja, A.; Khar, R.K.; Baboota, S. Floating Drug Delivery Systems: A Review. AAPS PharmSciTech, 2005, 6, 372-390.
19. Sher, P.; Ingavle, G.; Ponratnam, S.; Pawar, A. Low density porous carrier based conceptual drug delivery system. Microporous Mesoporous Mater., 2007, 102, 290-298. (Pubitemid 46603115)
20. Badve, S.S.; Sher, P.; Korde, A.; Pawar, A.P. Development of hollow/porous pectinate beads for floating-pulsatile drug delivery. Eur. J. Pharm. Biopharm., 2007, 65, 85-93.
21. Yong-Dan Tang, Y.D.; Venkatraman, S.S.; Boey, F.Y.C.; Wang, L.W. Sustained release of hydrophobic and hydrophilic drugs from a floating dosage form. Int. J. Pharm., 2007, 336, 159-165. (Pubitemid 46566484)
22. Ali, J.; Arora, S.; Ahuja, A.; Babbar, A.K.; Sharma, R.K.; Khar, R.K.; Baboota, S. Formulation and development of hydrodynamically balanced system for metformin: In vitro and in vivo evaluation. Eur. J. Pharm. Biopharm., 2007, 67, 196-201. (Pubitemid 46991323)
23. Mididoddi, P.K.; Repka, M.A. Characterization of hot-melt extruded drug delivery systems for onychomycosis. Eur. J. Pharm. Biopharm., 2007, 66, 95-105. (Pubitemid 46412960)
24. Bruce, L.D.; Shah, N.H.; Malick, A.W.; Infeld, M.H.; McGinty, J.W. Properties of hot-melt extruded tablet formulations for the colonic delivery of 5-aminosalicylic acid. Eur. J. Pharm. Biopharm., 2005, 59, 85-97.
25. Rouge, N.; All mann, E.; Gex-Fabry, M.; Balant, L.; Cole, E.T.; Buri, P.; Doelker, E. Comparative pharmacokinetic study of a floating multiple-unit capsule, a high density multiple-unit capsule and an immediate-release tablet containing 25mg atenolol. Pharmaceut. Acta Helv., 1998, 73, 81-87.
26. Bernkop-Schnürch, A. Mucoadhesive systems in oral drug delivery. Drug Discov. Today: Tech., 2005, 2, 83-87. (Pubitemid 40946312)
27. Tur, K.M.; Ch'ng, H.S. Evaluation of possible mechanism(s) of bioadhesion. Int. J. Pharm., 1998, 160, 61-74. (Pubitemid 28059930)
28. Thongborisute, J.; Takeuchi, H. Evaluation of mucoadhesiveness of polymers by BIACORE method and mucin-particle method. Int. J. Pharm., 2008, 354, 204-209.
29. Hoyer, H.; Schlocker, W.; Krum, K.; Bernkop-Schnürch, A. Preparation and evaluation of microparticles from thiolated polymers via air jet milling. Eur. J. Pharm. Biopharm., 2008, 69, 476-485.
30. Gröning, R.; Cloera, C.; Georgarakis, M.; Müller, R.S. Compressed collagen sponges as gastroretentive dosage forms: In vitro and in vivo studies. Eur. J. Pharm. Sci., 2007, 30, 1-6.
31. Caldwell, L.J.; Gardner, C.; Cargill, R.C.; Higuchi, T. Drug delivery device which can be retained in the stomach for a controlled period of time. US patent 4758436, July 19, 1988.
32. Curatolo, W.J.; Lo, J. Gastric retention system for controlled drug release. US Patent 5443843, August 22, 1995.
33. Sonobe, T.; Watanabe, S.; Katsuma, M.; Takamatsu, N.; Konno, Y.; Takagi, H. Gastric retention device. Eur. patent 0415671, March 13, 1991.
34. Kagan, L.; Lapidot, N.; Afargan, M.; Kirmayer, D.; Moor, E.; Mardor, Y.; Friedman, M.; Hoffman, A. Gastroretentive Accordion Pill: Enhancement of riboflavin bioavailability in humans. J. Control. Release, 2006, 113, 208-215.
35. Stops, F.; Fell, J.T.; Collett, J.H.; Martini, L.G.; Sharma, H.L.; Smith, A.M. The use of citric acid to prolong the in vivo gastro-retention of a floating dosage form in the fasted state. Int. J. Pharm., 2006, 308, 8-13. (Pubitemid 43097229)
36. Badve, S.S.; Sher, P.; Korde, A.; Pawar, A.P. Development of hollow/porous pectinate beads for floating-pulsatile drug delivery. Eur. J. Pharm. Biopharm., 2007, 65, 85-93.
37. Tuǧu-Demiröz, F.; Acartürk, F.; Takka, S.; Konu -Boyuna a, Ö. Evaluation of alginate based mesalazine tablets for intestinal drug delivery. Eur. J. Pharm. Biopharm., 2007, 67, 491-497. (Pubitemid 47211910)
38. Corá, L.A.; Romeiro, F.G.; Stelzer, M.; Américo, M.F.; Oliveira, R.B.; Baffa, O.; Miranda, J.R.A. AC biosusceptometry in the study of drug delivery. Adv. Drug Deliv. Rev., 2005, 57, 1223-1241.
39. Kagan, L.; Lapidot, N.; Afargan, M.; Kirmayer, D.; Moor E.; Mardor, Y. Friedman, M.; Hoffman, A. Gastroretentive Accordian Pill: Enhancement of riboflavin bioavailability in humans. J. Control. Release, 2006, 113, 208-215.
40. Corá, L.A.; Romero, F.G.; America, M.F.; Oliveira, R.B.; Biffa, O.; Seltzer, M.; de Aruba Miranda, J.R. Gastrointestinal transit and disintegration of enteric coated magnetic tablets assessed by ac biosusceptometry. Eur. J. Pharm. Sci., 2006, 27, 1-8. (Pubitemid 41728249)