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Volumn 58, Issue 2, 2010, Pages 544-550

Attenuation of morphine antinociceptive tolerance by a CB1 receptor agonist and an NMDA receptor antagonist: Interactive effects

Author keywords

Antinociception; Cannabinoid; CB1; Dose addition; Morphine; NMDA; Tolerance

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; DECAHYDRO 6 PHOSPHONOMETHYL 3 ISOQUINOLINECARBOXYLIC ACID; MORPHINE SULFATE;

EID: 72049125608     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2009.08.005     Document Type: Article
Times cited : (24)

References (45)
  • 1
    • 33745938930 scopus 로고    scopus 로고
    • Tolerance to morphine analgesia: evidence for stimulus intensity as a key factor and complete reversal by a glycine site-specific NMDA antagonist
    • Adam F., Bonnet F., and Le Bars D. Tolerance to morphine analgesia: evidence for stimulus intensity as a key factor and complete reversal by a glycine site-specific NMDA antagonist. Neuropharmacology 51 (2006) 191-202
    • (2006) Neuropharmacology , vol.51 , pp. 191-202
    • Adam, F.1    Bonnet, F.2    Le Bars, D.3
  • 2
    • 38649102166 scopus 로고    scopus 로고
    • The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism
    • Adam F., Dufour E., and Le Bars D. The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism. Neuropharmacology 54 (2008) 588-596
    • (2008) Neuropharmacology , vol.54 , pp. 588-596
    • Adam, F.1    Dufour, E.2    Le Bars, D.3
  • 3
    • 0033680193 scopus 로고    scopus 로고
    • Attenuation of mu-opioid tolerance and cross-tolerance by the competitive N-methyl-d-aspartate receptor antagonist LY235959 is related to tolerance and cross-tolerance magnitude
    • Allen R.M., and Dykstra L.A. Attenuation of mu-opioid tolerance and cross-tolerance by the competitive N-methyl-d-aspartate receptor antagonist LY235959 is related to tolerance and cross-tolerance magnitude. J. Pharmacol. Exp. Ther. 295 (2000) 1012-1021
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , pp. 1012-1021
    • Allen, R.M.1    Dykstra, L.A.2
  • 4
    • 25644452783 scopus 로고    scopus 로고
    • Effects of the competitive N-methyl-d-aspartate receptor antagonist, LY235959 [(-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid], on responding for cocaine under both fixed and progressive ratio schedules of reinforcement
    • Allen R.M., Carelli R.M., Dykstra L.A., Suchey T.L., and Everett C.V. Effects of the competitive N-methyl-d-aspartate receptor antagonist, LY235959 [(-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid], on responding for cocaine under both fixed and progressive ratio schedules of reinforcement. J. Pharmacol. Exp. Ther. 315 (2005) 449-457
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 449-457
    • Allen, R.M.1    Carelli, R.M.2    Dykstra, L.A.3    Suchey, T.L.4    Everett, C.V.5
  • 5
    • 34548489849 scopus 로고    scopus 로고
    • Continuous intracerebroventricular infusion of the competitive NMDA receptor antagonist, LY235959, facilitates escalation of cocaine self-administration and increases break point for cocaine in Sprague-Dawley rats
    • Allen R.M., Uban K.A., Atwood E.M., Albeck D.S., and Yamamoto D.J. Continuous intracerebroventricular infusion of the competitive NMDA receptor antagonist, LY235959, facilitates escalation of cocaine self-administration and increases break point for cocaine in Sprague-Dawley rats. Pharmacol. Biochem. Behav. 88 (2007) 82-88
    • (2007) Pharmacol. Biochem. Behav. , vol.88 , pp. 82-88
    • Allen, R.M.1    Uban, K.A.2    Atwood, E.M.3    Albeck, D.S.4    Yamamoto, D.J.5
  • 6
    • 0036867665 scopus 로고    scopus 로고
    • Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids
    • Alger B.E. Retrograde signaling in the regulation of synaptic transmission: focus on endocannabinoids. Prog. Neurobiol. 68 (2002) 247-286
    • (2002) Prog. Neurobiol. , vol.68 , pp. 247-286
    • Alger, B.E.1
  • 7
    • 0034044078 scopus 로고    scopus 로고
    • Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons
    • Auclair N., Otani S., Soubrie P., and Crepel F. Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons. J. Neurophysiol. 83 (2000) 3287-3293
    • (2000) J. Neurophysiol. , vol.83 , pp. 3287-3293
    • Auclair, N.1    Otani, S.2    Soubrie, P.3    Crepel, F.4
  • 8
    • 0017202327 scopus 로고
    • Effect of some cannabinoids on naloxone-precipitated abstinence in morphine-dependent mice
    • Bhargava H.N. Effect of some cannabinoids on naloxone-precipitated abstinence in morphine-dependent mice. Psychopharmacology (Berl.) 49 (1976) 267-270
    • (1976) Psychopharmacology (Berl.) , vol.49 , pp. 267-270
    • Bhargava, H.N.1
  • 9
    • 3042542729 scopus 로고    scopus 로고
    • Endocannabinoids inhibit transmission at granule cell to Purkinje cell synapses by modulating three types of presynaptic calcium channels
    • Brown S.P., Safo P.K., and Regehr W.G. Endocannabinoids inhibit transmission at granule cell to Purkinje cell synapses by modulating three types of presynaptic calcium channels. J. Neurosci. 24 (2004) 5623-5631
    • (2004) J. Neurosci. , vol.24 , pp. 5623-5631
    • Brown, S.P.1    Safo, P.K.2    Regehr, W.G.3
  • 11
    • 0037512412 scopus 로고    scopus 로고
    • Modulation of oral morphine antinociceptive tolerance and naloxone-precipitated withdrawal signs by oral Delta 9-tetrahydrocannabinol
    • Cichewicz D.L., and Welch S.P. Modulation of oral morphine antinociceptive tolerance and naloxone-precipitated withdrawal signs by oral Delta 9-tetrahydrocannabinol. J. Pharmacol. Exp. Ther. 305 (2003) 812-817
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 812-817
    • Cichewicz, D.L.1    Welch, S.P.2
  • 12
    • 2342498975 scopus 로고    scopus 로고
    • 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): a novel cannabinoid Cb1/Cb2 receptor partial agonist with antihyperalgesic and antiallodynic effects
    • De Vry J., Denzer D., Reissmueller E., Eijckenboom M., Heil M., Meier H., and Mauler F. 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): a novel cannabinoid Cb1/Cb2 receptor partial agonist with antihyperalgesic and antiallodynic effects. J. Pharmacol. Exp. Ther. 310 (2004) 620-632
    • (2004) J. Pharmacol. Exp. Ther. , vol.310 , pp. 620-632
    • De Vry, J.1    Denzer, D.2    Reissmueller, E.3    Eijckenboom, M.4    Heil, M.5    Meier, H.6    Mauler, F.7
  • 13
    • 0000510767 scopus 로고    scopus 로고
    • Assessing transient and persistent pain in animals
    • Wall P.D., and Melzack R. (Eds), Churchill Livingstone, Edinburgh, UK
    • Dubner R., and Ren K. Assessing transient and persistent pain in animals. In: Wall P.D., and Melzack R. (Eds). Textbook of Pain (1999), Churchill Livingstone, Edinburgh, UK 359-369
    • (1999) Textbook of Pain , pp. 359-369
    • Dubner, R.1    Ren, K.2
  • 14
    • 0037661996 scopus 로고    scopus 로고
    • Role of endogenous cannabinoids in synaptic signaling
    • Freund T.F., Katona I., and Piomelli D. Role of endogenous cannabinoids in synaptic signaling. Physiol. Rev. 83 (2003) 1017-1066
    • (2003) Physiol. Rev. , vol.83 , pp. 1017-1066
    • Freund, T.F.1    Katona, I.2    Piomelli, D.3
  • 15
    • 33747620315 scopus 로고    scopus 로고
    • Interactions between an NMDA antagonist and low-efficacy opioid receptor agonists in assays of schedule-controlled responding and thermal nociception
    • Fischer B.D., and Dykstra L.A. Interactions between an NMDA antagonist and low-efficacy opioid receptor agonists in assays of schedule-controlled responding and thermal nociception. J. Pharmacol. Exp. Ther. 318 (2006) 1300-1306
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 1300-1306
    • Fischer, B.D.1    Dykstra, L.A.2
  • 16
    • 38749131191 scopus 로고    scopus 로고
    • Morphine in combination with metabotropic glutamate receptor antagonists on schedule-controlled responding and thermal nociception
    • Fischer B.D., Zimmerman E.I., Picker M.J., and Dykstra L.A. Morphine in combination with metabotropic glutamate receptor antagonists on schedule-controlled responding and thermal nociception. J. Pharmacol. Exp. Ther. 324 (2008) 732-739
    • (2008) J. Pharmacol. Exp. Ther. , vol.324 , pp. 732-739
    • Fischer, B.D.1    Zimmerman, E.I.2    Picker, M.J.3    Dykstra, L.A.4
  • 17
    • 34249780096 scopus 로고    scopus 로고
    • CB1 receptors diminish both Ca(2+) influx and glutamate release through two different mechanisms active in distinct populations of cerebrocortical nerve terminals
    • Godino M.C., Torres M., and Sánchez-Prieto J. CB1 receptors diminish both Ca(2+) influx and glutamate release through two different mechanisms active in distinct populations of cerebrocortical nerve terminals. J. Neurochem. 101 (2007) 1471-1482
    • (2007) J. Neurochem. , vol.101 , pp. 1471-1482
    • Godino, M.C.1    Torres, M.2    Sánchez-Prieto, J.3
  • 18
    • 0016427104 scopus 로고
    • Morphine-dependent rats: blockade of precipitated abstinence by tetrahydrocannabinol
    • Hine B., Friedman E., Torrelio M., and Gershon S. Morphine-dependent rats: blockade of precipitated abstinence by tetrahydrocannabinol. Science 187 (1975) 443-445
    • (1975) Science , vol.187 , pp. 443-445
    • Hine, B.1    Friedman, E.2    Torrelio, M.3    Gershon, S.4
  • 19
    • 0042844731 scopus 로고    scopus 로고
    • Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence
    • Inoue M., Mishina M., and Ueda H. Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence. J. Neurosci. 23 (2003) 6529-6536
    • (2003) J. Neurosci. , vol.23 , pp. 6529-6536
    • Inoue, M.1    Mishina, M.2    Ueda, H.3
  • 20
    • 0037278221 scopus 로고    scopus 로고
    • Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-d-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice
    • Kozela E., Pilc A., and Popik P. Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-d-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice. Psychopharmacology (Berl.) 165 (2003) 245-251
    • (2003) Psychopharmacology (Berl.) , vol.165 , pp. 245-251
    • Kozela, E.1    Pilc, A.2    Popik, P.3
  • 21
    • 0035053627 scopus 로고    scopus 로고
    • Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells
    • Kreitzer A.C., and Regehr W.G. Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron 29 (2001) 717-727
    • (2001) Neuron , vol.29 , pp. 717-727
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 23
    • 0034893982 scopus 로고    scopus 로고
    • Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice
    • Lichtman A.H., Sheikh S.M., Loh H.H., and Martin B.R. Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice. J. Pharmacol. Exp. Ther. 298 (2001) 1007-1014
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 1007-1014
    • Lichtman, A.H.1    Sheikh, S.M.2    Loh, H.H.3    Martin, B.R.4
  • 24
    • 38949123202 scopus 로고    scopus 로고
    • NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats
    • Mendez I.A., and Trujillo K.A. NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats. Psychopharmacology (Berl.) 196 (2008) 497-509
    • (2008) Psychopharmacology (Berl.) , vol.196 , pp. 497-509
    • Mendez, I.A.1    Trujillo, K.A.2
  • 25
    • 34447525394 scopus 로고    scopus 로고
    • Animal model of schizophrenia: dysfunction of NMDA receptor-signaling in mice following withdrawal from repeated administration of phencyclidine
    • Nabeshima T., Mouri A., Murai R., and Noda Y. Animal model of schizophrenia: dysfunction of NMDA receptor-signaling in mice following withdrawal from repeated administration of phencyclidine. Ann. N. Y. Acad. Sci. 1086 (2006) 160-168
    • (2006) Ann. N. Y. Acad. Sci. , vol.1086 , pp. 160-168
    • Nabeshima, T.1    Mouri, A.2    Murai, R.3    Noda, Y.4
  • 27
    • 0035179658 scopus 로고    scopus 로고
    • NMDA receptor regulation of memory and behavior in humans
    • Newcomer J.W., and Krystal J.H. NMDA receptor regulation of memory and behavior in humans. Hippocampus 11 (2001) 529-542
    • (2001) Hippocampus , vol.11 , pp. 529-542
    • Newcomer, J.W.1    Krystal, J.H.2
  • 28
    • 0037095762 scopus 로고    scopus 로고
    • Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses
    • Ohno-Shosaku T., Tsubokawa H., Mizushima I., Yoneda N., Zimmer A., and Kano M. Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses. J. Neurosci. 22 (2002) 3864-3872
    • (2002) J. Neurosci. , vol.22 , pp. 3864-3872
    • Ohno-Shosaku, T.1    Tsubokawa, H.2    Mizushima, I.3    Yoneda, N.4    Zimmer, A.5    Kano, M.6
  • 29
    • 0035050883 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals
    • Ohno-Shosaku T., Maejima T., and Kano M. Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals. Neuron 29 (2001) 729-738
    • (2001) Neuron , vol.29 , pp. 729-738
    • Ohno-Shosaku, T.1    Maejima, T.2    Kano, M.3
  • 30
    • 37049023653 scopus 로고    scopus 로고
    • Antinociceptive effect and interaction of uncompetitive and competitive NMDA receptor antagonists upon capsaicin and paw pressure testing in normal and monoarthritic rats
    • Pelissier T., Infante C., Constandil L., Espinosa J., Lapeyra C.D., and Hernández A. Antinociceptive effect and interaction of uncompetitive and competitive NMDA receptor antagonists upon capsaicin and paw pressure testing in normal and monoarthritic rats. Pain 134 (2008) 113-127
    • (2008) Pain , vol.134 , pp. 113-127
    • Pelissier, T.1    Infante, C.2    Constandil, L.3    Espinosa, J.4    Lapeyra, C.D.5    Hernández, A.6
  • 31
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoid receptors and pain
    • Pertwee R.G. Cannabinoid receptors and pain. Prog. Neurobiol. 63 (2001) 569-611
    • (2001) Prog. Neurobiol. , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 32
    • 0036784507 scopus 로고    scopus 로고
    • N-Methyl-d-aspartate antagonists and WIN 55212-2 [4,5-dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1-i, j]quinolin-6-one], a cannabinoid agonist, interact to produce synergistic hypothermia
    • Rawls S.M., Cowan A., Tallarida R.J., Geller E.B., and Adler M.W. N-Methyl-d-aspartate antagonists and WIN 55212-2 [4,5-dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1-i, j]quinolin-6-one], a cannabinoid agonist, interact to produce synergistic hypothermia. J. Pharmacol. Exp. Ther. 303 (2002) 395-402
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 395-402
    • Rawls, S.M.1    Cowan, A.2    Tallarida, R.J.3    Geller, E.B.4    Adler, M.W.5
  • 34
    • 34548483418 scopus 로고    scopus 로고
    • Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors
    • Smith P.A., Selley D.E., Sim-Selley L.J., and Welch S.P. Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors. Eur. J. Pharmacol. 571 (2007) 129-137
    • (2007) Eur. J. Pharmacol. , vol.571 , pp. 129-137
    • Smith, P.A.1    Selley, D.E.2    Sim-Selley, L.J.3    Welch, S.P.4
  • 36
    • 0345599257 scopus 로고    scopus 로고
    • Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception
    • Stevenson G.W., Folk J.E., Linsenmayer D.C., Rice K.C., and Negus S.S. Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception. J. Pharmacol. Exp. Ther. 307 (2003) 1054-1064
    • (2003) J. Pharmacol. Exp. Ther. , vol.307 , pp. 1054-1064
    • Stevenson, G.W.1    Folk, J.E.2    Linsenmayer, D.C.3    Rice, K.C.4    Negus, S.S.5
  • 37
    • 23044473575 scopus 로고    scopus 로고
    • Interactions between δ and μ opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: studies with SNC80 [(+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N, N-diethylbenzamide] and heroin
    • Stevenson G.W., Folk J.E., Rice K.C., and Negus S.S. Interactions between δ and μ opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: studies with SNC80 [(+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N, N-diethylbenzamide] and heroin. J. Pharmacol. Exp. Ther. 314 (2005) 221-231
    • (2005) J. Pharmacol. Exp. Ther. , vol.314 , pp. 221-231
    • Stevenson, G.W.1    Folk, J.E.2    Rice, K.C.3    Negus, S.S.4
  • 39
    • 0036299135 scopus 로고    scopus 로고
    • The interaction index: a measure of drug synergism
    • Tallarida R.J. The interaction index: a measure of drug synergism. Pain 98 (2002) 163-168
    • (2002) Pain , vol.98 , pp. 163-168
    • Tallarida, R.J.1
  • 40
    • 0030732241 scopus 로고    scopus 로고
    • Theory and statistics of detecting synergism between two active drugs: cocaine and buprenorphine
    • Tallarida R.J., Kimmel H.L., and Holtzman S.G. Theory and statistics of detecting synergism between two active drugs: cocaine and buprenorphine. Psychopharmacology (Berl.) 133 (1997) 378-382
    • (1997) Psychopharmacology (Berl.) , vol.133 , pp. 378-382
    • Tallarida, R.J.1    Kimmel, H.L.2    Holtzman, S.G.3
  • 41
    • 0033847254 scopus 로고    scopus 로고
    • Are NMDA receptors involved in opiate-induced neural and behavioral plasticity? A review of preclinical studies
    • Trujillo K.A. Are NMDA receptors involved in opiate-induced neural and behavioral plasticity? A review of preclinical studies. Psychopharmacology (Berl.) 151 (2000) 121-141
    • (2000) Psychopharmacology (Berl.) , vol.151 , pp. 121-141
    • Trujillo, K.A.1
  • 42
    • 12444281775 scopus 로고    scopus 로고
    • New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia
    • Ujike H., and Morita Y. New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia. J. Pharmacol. Sci. 96 (2004) 376-381
    • (2004) J. Pharmacol. Sci. , vol.96 , pp. 376-381
    • Ujike, H.1    Morita, Y.2
  • 43
    • 0029048756 scopus 로고
    • Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine
    • Vela G., Ruiz-Gayo M., and Fuentes J.A. Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. Neuropharmacology 34 (1995) 665-668
    • (1995) Neuropharmacology , vol.34 , pp. 665-668
    • Vela, G.1    Ruiz-Gayo, M.2    Fuentes, J.A.3
  • 44
    • 42449164739 scopus 로고    scopus 로고
    • Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in mice
    • Ward S.J., Lefever T.W., Jackson C., Tallarida R.J., and Walker E.A. Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in mice. J. Pharmacol. Exp. Ther. 325 (2008) 567-576
    • (2008) J. Pharmacol. Exp. Ther. , vol.325 , pp. 567-576
    • Ward, S.J.1    Lefever, T.W.2    Jackson, C.3    Tallarida, R.J.4    Walker, E.A.5
  • 45
    • 48049095955 scopus 로고    scopus 로고
    • The cannabinoid CB(1) receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task
    • Wise L.E., Iredale P.A., and Lichtman A.H. The cannabinoid CB(1) receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task. Eur. J. Pharmacol. 590 (2008) 246-249
    • (2008) Eur. J. Pharmacol. , vol.590 , pp. 246-249
    • Wise, L.E.1    Iredale, P.A.2    Lichtman, A.H.3


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