N-methyl-D-aspartate antagonists and WIN 55212-2 [4,5-dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl) -6H-pyrrolo[3,2,1-i,j]quinolin-6-one], a cannabinoid agonist, interact to produce synergistic hypothermia

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 1, 2002, Pages 395-402

  Rawls, Scott M ^a   Cowan, A ^a   Tallarida, R J ^a   Geller, Ellen B ^a   Adler, Martin W ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; DECAHYDRO 6 PHOSPHONOMETHYL 3 ISOQUINOLINECARBOXYLIC ACID; DEXTROMETHORPHAN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

AGONIST; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; DRUG RESPONSE; HYPOTHERMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BODY TEMPERATURE; CALCIUM CHANNEL BLOCKERS; CANNABINOIDS; DEXTROMETHORPHAN; DRUG SYNERGISM; EXCITATORY AMINO ACID ANTAGONISTS; HYPOTHERMIA; ISOQUINOLINES; KINETICS; MORPHOLINES; N-METHYLASPARTATE; NAPHTHALENES; RATS; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036784507     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.037473     Document Type: Article

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