Oxidative stress and apoptosis are induced in human endothelial cells exposed to urban particulate matter

Toxicology in Vitro

Volumn 24, Issue 1, 2010, Pages 135-141

  Montiel Dávalos, Angélica ^a   Ibarra Sánchez, María de Jesús ^b   Ventura Gallegos, José Luis ^c   Alfaro Moreno, Ernesto ^d   López Marure, Rebeca ^a  

^a INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^b INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

^d INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

Author keywords

Endothelial cells; Inflammation; NF B; Oxidative stress; Particulate matter; TNF

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; ENDOTHELIUM CELL; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; MEXICO; OXIDATIVE STRESS; PARTICLE SIZE; PARTICULATE MATTER; PROTEIN LOCALIZATION; URBAN AREA;

APOPTOSIS; CELL DEATH; CELL LINE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIAL CELLS; FEMALE; HUMANS; NF-KAPPA B; NITRIC OXIDE; OXIDATIVE STRESS; PARTICLE SIZE; PARTICULATE MATTER; REACTIVE OXYGEN SPECIES; TRANSLOCATION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 72049115240     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.08.004     Document Type: Article

References (54)

1. Alfaro-Moreno E., Martínez L., García-Cuellar C., Bonner J.C., Murray J.C., Rosas I., Rosales S.P., and Osornio-Vargas A.R. Biologic effects induced in vitro by PM10 from three different zones of Mexico City. Environ. Health Perspect. 110 (2002) 715-720
2. Alfaro-Moreno E., Nawrot T.S., Nemmar A., and Nemery B. Particulate matter in the environment: pulmonary and cardiovascular effects. Curr. Opin. Pulm. Med. 13 (2007) 98-106
3. Alfaro-Moreno E., López-Marure R., Montiel-Dávalos A., Symonds P., Osornio-Vargas A.R., Rosas I., and Clifford-Murray J. E-Selectin expression in human endothelial cells exposed to PM10: the role of endotoxin and insoluble fraction. Environ. Res. 103 (2007) 221-228
4. Alfaro-Moreno E., Ponce-de-León-Rosales S., Osornio-Vargas A.R., García-Cuellar C., Martínez L., and Rosas I. Potential toxic effects associated to metals and endotoxin present in PM10. An ancillary study using multivariate analysis. Inhal. Toxicol. 19 (2007) 49-53
5. Alfaro-Moreno E., Nawrot T.S., Vanaudenaerde B., Hoylaerts M., Vanoirbeek J., Verbeken E., Nemery B., and Hoet P.H.M. Multiple co-cultures mimic pulmonary cell communication in response to urban PM10. Eur. Respir. J. 32 (2008) 1184-1194
6. Alfaro-Moreno E., Torres V., Miranda J., Martínez L., García-Cuellar C., Nawrot T.S., Vanaudenaerde B., Hoet P., Ramírez-López P., Rosas I., Nemery B., and Osornio-Vargas A.R. Induction of IL-6 and inhibition of IL-8 secretion in the human airway cell line Calu-3 by urban particulate matter collected with a modified method of PM sampling. Environ. Res. 109 (2009) 528-535
7. Amano F., and Noda T. Improved detection of nitric oxide radical (NO) production in an activated macrophage culture with a radical scavenger, carboxy PTIO and Griess reagent. FEBS Lett. 368 (1995) 425-428
8. Baeza-Squiban A., Bonvallot V., Boland S., and Marano F. Airbone particles evoke and inflammatory response in human airway epithelium. Activation of transcription factors. Cell Biol. Toxicol. 15 (1999) 375-380
9. Becker S., Fenton M.J., and Soukup J.M. Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles. Am. J. Respir. Cell Mol. Biol. 27 (2002) 611-618
10. Becker S., Dailey L.A., Soukup J.M., Grambow S.C., Devlin R.B., and Huang Y.C.T. Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress. Environ. Health Perspect. 113 (2005) 1032-1038
11. Bonner J.C., Rice A.B., Lindroos P.M., O'Brien P.O., Dreher K.L., Rosas I., Alfaro-Moreno E., and Osornio-Vargas A.R. Induction of the lung myofibroblast PDGF receptor system by urban ambient particles from Mexico City. Am. J. Respir. Cell Mol. Biol. 19 (1998) 672-680
12. Calcabrini A., Meschini S., Marra M., Falzano L., Colone M., De Berardis B., Paoletti L., Arancia G., and Fiorentini C. Fine environmental particulate engenders alterations in human lung epithelial A549 cells. Environ. Res. 95 (2004) 82-91
13. Chin B.Y., Choi M.E., Burdick M.D., Strieter R.M., Risby T.H., and Choi A.M. Induction of apoptosis by particulate matter: role of TNF-alpha and MAPK. Am. J. Physiol. 275 (1998) 942-949
14. Choi J.H., Kim J.S., Kim Y.C., Kim Y.S., Chung N.H., and Cho M.H. Comparative study of PM2.5 and PM10-induced oxidative stress in rat lung epithelial cells. J. Vet. Sci. 5 (2005) 11-18
15. Chu Q., Yang K., and Wang A. Research progress on oxidative stress and apoptosis. Wei. Sheng. Yan. Jiu. 32 (2003) 276-279
16. Dagher Z., Garcon G., Gosset P., Ledoux F., Surpateanu G., Courcot D., Aboukais A., Puskaric E., and Shirali P. Pro-inflammatory effects of Dunkerque city air pollution particulate matter 2.5 in human epithelial lung cells (L132) in culture. J. Appl. Toxicol. 25 (2005) 166-175
17. Dagher Z., Garçon G., Billet S., Gosset P., Ledoux F., Courcot D., Aboukais A., and Shirali P. Activation of different pathways of apoptosis by air pollution particulate matter (PM2.5) in human epithelial lung cells (L132) in culture. Toxicology 225 (2006) 12-24
18. Dagher Z., Garcon G., Billet S., Verdin A., Ledoux F., Courcot D., Aboukais A., and Shirali P.J. Role of nuclear factor-kappa B activation in the adverse effects induced by air pollution particulate matter (PM2.5) in human epithelial lung cells (L132) in culture. Appl. Toxicol. 27 (2007) 284-290
19. de Martin R., Schmid J.A., and Hofer-Warbinek R. The NF-κB/Rel family of transcription factors in oncogenic transformation and apoptosis. Mutat. Res. 437 (1999) 231-243
20. de Vizcaya-Ruiz A., Gutiérrez-Castillo M.E., Uribe-Ramirez M., Cebrián M.E., Mugica-Alvarez V., Sepúlveda J., Rosas I., Salinas E., Garcia-Cuéllar C., Martínez F., Alfaro-Moreno E., Torres-Flores V., Osornio-Vargas A., Sioutas C., Fine P.M., Singh M., Geller M.D., Kuhn T., Eiguren-Fernandez A., Miguel A., Schiestl R., Reliene R., and Froines J. Characterization and in vitro biological effects of concentrated particulate matter from Mexico City. Atmos. Environ. 40 (2006) S583-S592
21. Delfino R.J., Sioutas C., and Malik S. Potential role of ultrafine particles in associations between airborne particle mass and cardiovascular health. Environ. Health Perspect. 113 (2005) 934-946
22. Diociaiuti M., Balduzzi M., De Berardis B., Cattani G., Stacchini G., Ziemacki G., Marconi A., and Paoletti L. The two PM(2.5) (fine) and PM(2.5-10) (coarse) fractions: evidence of different biological activity. Environ. Res. 86 (2001) 254-262
23. Furuyama A., Hirano S., Koike E., and Kobayashi T. Induction of oxidative stress and inhibition of plasminogen activator inhibitor-1 production in endothelial cells following exposure to organic extracts of diesel exhaust particles and urban fine particles. Arch. Toxicol. 80 (2006) 154-162
24. Gutiérrez-Castillo M.E., Roubicek D.A., Cebrián-García M.E., De Vizcaya-Ruíz A., Sordo-Cedeño M., and Ostrosky-Wegman P. Effect of chemical composition on the induction of DNA damage by urban airborne particulate matter. Environ. Mol. Mutagen. 47 (2006) 199-211
25. Hetland R.B., Cassee F.R., Refsnes M., Schwarze P.E., Lag M., Boere A.J., and Dybing E. Release of inflammatory cytokines, cell toxicity and apoptosis in epithelial lung cells after exposure to ambient air particles of different size fractions. Toxicol. In Vitro 18 (2004) 203-212
26. Hetland R.B., Cassee F.R., Låg M., Refsnes M., Dybing E., and Schwarze P.E. Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season. Part. Fibre Toxicol. 17 (2005) 2-4
27. Huang Y.C., Li Z., Harder S.D., and Soukup J.M. Apoptotic and inflammatory effects induced by different particles in human alveolar macrophages. Inhal. Toxicol. 16 (2004) 863-878
28. Jalava P.I., Salonen R.O., Pennanen A.S., Sillanpa M., Halinen A.I., Happo M.S., Hillamo R., Brunekreef B., Katsouyanni K., Sunyer J., and Hirvonen M.R. Heterogeneities in inflammatory and cytotoxic response of RAW 264.7 macrophage cell line to urban air coarse, fine, and untrafine particles from six European sampling campaigns. Inhal. Toxicol. 19 (2007) 213-225
29. Jalava P.I., Salonen R.O., Pennanen A.S., Happo M.S., Penttinen P., Hälinen A.I., Sillanpää M., Hillamo R., and Hirvonen M.R. Effects of solubility of urban air fine and coarse particles on cytotoxic and inflammatory responses in RAW 264.7 macrophage cell line. Toxicol. Appl. Pharmacol. 229 (2008) 146-160
30. Lenardo M.J., and Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58 (1989) 227-229
31. Li X.Y., Gilmour P.S., Donaldson K., and MacNee W. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax 51 (1996) 1216-1222
32. Li Z., Carter J.D., Dailey L.A., and Huang Y.C. Pollutant particles produce vasoconstriction and enhance MAPK signaling via angiotensin type 1 receptor. Environ. Health Perspect. 113 (2005) 1009-1014
33. Li Z., Hyseni X., Carter J.D., Dailey L.A., and Huang Y.C. Pollutant particles enhanced hydrogen peroxide production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. Am. J. Physiol. Cell Physiol. 291 (2006) C357-C365
34. Lubos E., Handy D.E., and Loscalzo J. Role of oxidative stress and nitric oxide in atherothrombosis. Front. Biosci. 13 (2008) 5323-5344
35. Martin L.D., Krunkosky T.M., Dye J.A., Fischer B.M., Jiang N.F., Rochelle L.G., Akley N.J., Dreher K.L., and Adler K.B. The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates. Environ. Health Perspect. 105 (1997) 1301-1307
36. Molinelli A.R., Santacana G.E., Madden M.C., and Jiménez B.D. Toxicity and metal content of organic solvent extracts from airborne particulate matter in Puerto Rico. Environ. Res. 102 (2006) 314-325
37. 10 induce the expression of adhesion molecules and the adhesion of monocytic cells to human umbilical vein endothelial cells. Inhal. Toxicol. 1 (2007) 91-98
38. Nam H.Y., Choi B.H., Lee J.Y., Lee S.G., Kim Y.H., Lee K.H., Yoon H.K., Song J.S., Kim H.J., and Lim Y. The role of nitric oxide in the particulate matter (PM2.5)-induced NFkappaB activation in lung epithelial cells. Toxicol. Lett. 148 (2004) 95-102
39. Napoli C., de Nigris F., and Palinski W. Multiple role of reactive oxygen species in the arterial wall. J. Cell Biochem. 82 (2001) 674-682
40. Nemmar A., Hoet P.H., Vanquickenborne B., Dinsdale D., Thomeer M., Hoylaerts M.F., Vanbilloen H., Mortelmans L., and Nemery B. Passage of inhaled particles into the blood circulation in humans. Circulation 105 (2002) 411-414
41. Nurkiewicz T.R., Porter D.W., Barger M., Millecchia L., Rao K.M., Marvar P.J., Hubbs A.F., Castranova V., and Boegehold M.A. Systemic microvascular dysfunction and inflammation after pulmonary particulate matter exposure. Environ. Health Perspect. 114 (2006) 412-419
42. Ogita H., and Liao J. Endothelial function and oxidative stress. Endothelium 11 (2004) 123-132
43. Osornio-Vargas A.R., Bonner J.C., Alfaro-Moreno E., Martinez L., Garcia-Cuellar C., Ponce de León-Rosales S., Miranda J., and Rosas I. Proinflammatory and cytotoxic effects of Mexico City air pollution particulate matter in vitro are dependent on particle size and composition. Environ. Health Perspect. 111 (2003) 1289-1293
44. Pope C.A., and Dockery D.W. Health effects of fine particulate air pollution: lines that connect. J. Air Waste Manag. Assoc. 56 (2006) 709-742
45. Rosas-Pérez I., Serrano J., Alfaro-Moreno E., Baumgardner D., García-Cuellar C., Martín Del Campo J.M., Raga G.B., Castillejos M., Colín R.D., and Osornio-Vargas A.R. Relations between PM10 composition and cell toxicity: a multivariate and graphical approach. Chemosphere 67 (2007) 1218-1228
46. Shi T., Duffin R., Borm P.J., Li H., Weishaupt C., and Schins R.P. Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations. Environ. Res. 101 (2006) 18-24
47. Soberanes S., Panduri V., Mutlu G.M., Ghio A., Bundinger G.R., and Kamp D.W. P53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis. Am. J. Respir. Crit. Care Med. 174 (2006) 1229-1238
48. Tao F., Gonzalez-Flecha B., and Kobzik L. Reactive oxygen species in pulmonary inflammation by ambient particulars. Free Radical. Biol. Med. 35 (2003) 327-340
49. van Eeden S.F., Yeung A., Quinlam K., and Hogg J.C. Systemic response to ambient particulate matter. Relevance to chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2 (2005) 61-67
50. Veranth J.M., Moss T.A., Chow J.C., Labb R., Nichols W.K., Walton J.C., Watson J.G., and Yost G.S. Correlation of in vitro cytokine responses with the chemical composition of soil-derived particulate matter. Environ. Health Perspect. 114 (2006) 341-349
51. Weber C., and Erl W. Modulation of vascular cell activation, function, and apoptosis: role of antioxidants and nuclear factor-kappa B. Curr. Top. Cell Regul. 36 (2000) 217-235
52. Xia T., Kovochich M., and Nel A.E. Impairment of mitochondrial function by particulate matter (PM) and their toxic components: implications for PM-induced cardiovascular and lung disease. Front. Biosci. 12 (2007) 1238-1246
53. Zapata E., Ventura J.L., De la Cruz K., Rodriguez E., Damián P., Massó F., Montaño L.F., and López-Marure R. Dehydroepiandrosterone inhibits the proliferation of human umbilical vein endothelial cells by enhancing the expression of p53 and p21, restricting the phosphorylation of retinoblastoma protein, and is androgen- and estrogen-receptor independent. FEBS J. 272 (2005) 1343-1353
54. Zhang J., Ghio A.J., Chang W., Kamdar O., Rosen G.D., and Upadhyay D. Bim mediates mitochondria-regulated particulate matter-induced apoptosis in alveolar epithelial cells. FEBS Lett. 581 (2007) 4148-4152