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ChemMedChem

Volumn 4, Issue 11, 2009, Pages 1806-1809

Identification and validation of a potent type II inhibitor of inactive polo-like kinase 1

(4) Keppner, Sarah a Proschak, Ewgenij a Schneider, Gisbert a Spänkuch, Birgit a

a GOETHE UNIVERSITY (Germany)

Author keywords

Antitumor agents; Computational chemistry; Drug discovery; Enzyme inhibitors; Kinases

Indexed keywords

POLO LIKE KINASE 1; POLO LIKE KINASE 1 INHIBITOR; PROTEIN SERINE THREONINE KINASE INHIBITOR; SBE 13; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN CONFORMATION;

BINDING SITES; CELL CYCLE PROTEINS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HELA CELLS; HUMANS; HYDROGEN BONDING; MODELS, CHEMICAL; PHENETHYLAMINES; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PYRIDINES;

EID: 72049100230 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200900338 Document Type: Article

Times cited : (40)

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