Distinct Signaling Pathways After Higher or Lower Doses of Radiation in Three Closely Related Human Lymphoblast Cell Lines

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 1, 2010, Pages 212-219

  Lu, Tzu Pin ^a   Lai, Liang Chuan ^a   Lin, Be I ^a   Chen, Li Han ^a   Hsiao, Tzu Hung ^a   Liber, Howard L ^b   Cook, John A ^c   Mitchell, James B ^c   Tsai, Mong Hsun ^a   Chuang, Eric Y ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Human lymphoblast cells; Microarray; p53; Radiation; Signaling pathway

Indexed keywords

CELL LINES; CELLULAR RESPONSE; DIFFERENTIAL EXPRESSIONS; DNA DAMAGES; GENE EXPRESSION PATTERNS; HIER-ARCHICAL CLUSTERING; HUMAN LYMPHOBLAST CELLS; IN-CELL; PRINCIPLE COMPONENT ANALYSIS; RADIATION EXPOSURE; RADIATION TREATMENTS; SIGNALING PATHWAYS; TEMPLATE-BASED; TRANSCRIPTIONAL RESPONSE; TUMOR SUPPRESSORS; WILD TYPES;

CELL CULTURE; CELLS; GENE EXPRESSION; IONIZING RADIATION; MICROARRAYS; NUCLEIC ACIDS; PIGMENTS; RADIOTHERAPY;

SIGNALING;

PROTEIN P53;

ARTICLE; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOBLAST; PRIORITY JOURNAL; RADIATION DOSE; RNA EXTRACTION;

CELL LINE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; E2F4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; GENE SILENCING; GENES, P53; HUMANS; LYMPHOCYTES; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 72049091186     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.08.015     Document Type: Article

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