-
1
-
-
0032076190
-
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome
-
R. Varon, C. Vissinga, M. Platzer, K. M. Cerosaletti, K. H. Chrzanowska, K. Saar, G. Beckmann, E. Seemanova, P. R. Cooper and A. Reis, Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell 93, 467-476 (1998).
-
(1998)
Cell
, vol.93
, pp. 467-476
-
-
Varon, R.1
Vissinga, C.2
Platzer, M.3
Cerosaletti, K.M.4
Chrzanowska, K.H.5
Saar, K.6
Beckmann, G.7
Seemanova, E.8
Cooper, P.R.9
Reis, A.10
-
2
-
-
17344372572
-
Positional cloning of the gene for Nijmegen breakage syndrome
-
S. Matsuura, H. Tauchi, A. Nakamura, N. Kondo, S. Sakamoto, S. Endo, D. Smeets, B. Solder, B. H. Belohradsky and K. Komatsu, Positional cloning of the gene for Nijmegen breakage syndrome. Nat. Genet. 19, 179-181 (1998).
-
(1998)
Nat. Genet.
, vol.19
, pp. 179-181
-
-
Matsuura, S.1
Tauchi, H.2
Nakamura, A.3
Kondo, N.4
Sakamoto, S.5
Endo, S.6
Smeets, D.7
Solder, B.8
Belohradsky, B.H.9
Komatsu, K.10
-
3
-
-
0032076248
-
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
-
J. P. Carney, R. S. Maser, H. Olivares, E. M. Davis, M. Le Beau, J. R. Yates, 3rd, L. Hays, W. F. Morgan and J. H. Petrini, The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response. Cell 93, 477-486 (1998).
-
(1998)
Cell
, vol.93
, pp. 477-486
-
-
Carney, J.P.1
Maser, R.S.2
Olivares, H.3
Davis, E.M.4
Le Beau, M.5
Yates III, J.R.6
Hays, L.7
Morgan, W.F.8
Petrini, J.H.9
-
4
-
-
0031773760
-
Identification of genes involved in repair of DNA double-strand breaks in mammalian cells
-
P. A. Jeggo, Identification of genes involved in repair of DNA double-strand breaks in mammalian cells. Radiat. Res. 150 (Suppl.), S80-S91 (1998).
-
(1998)
Radiat. Res.
, vol.150
, Issue.SUPPL.
-
-
Jeggo, P.A.1
-
5
-
-
0034195218
-
Partners and pathways repairing a double-strand break
-
J. E. Haber, Partners and pathways repairing a double-strand break. Trends Genet. 16, 259-264 (2000).
-
(2000)
Trends Genet.
, vol.16
, pp. 259-264
-
-
Haber, J.E.1
-
6
-
-
0034031137
-
DNA double strand break repair in mammalian cells
-
P. Karran, DNA double strand break repair in mammalian cells. Curr. Opin. Genet. 10, 144-150 (2000).
-
(2000)
Curr. Opin. Genet.
, vol.10
, pp. 144-150
-
-
Karran, P.1
-
7
-
-
0037038362
-
Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells
-
H. Tauchi, J. Kobayashi, K. Morishima, D. C. van Gent, T. Shiraishi, N. S. Verkaik, D. van Heems, E. Ito, A. Nakamura and K. Komatsu, Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells. Nature 420, 93-98 (2002).
-
(2002)
Nature
, vol.420
, pp. 93-98
-
-
Tauchi, H.1
Kobayashi, J.2
Morishima, K.3
Van Gent, D.C.4
Shiraishi, T.5
Verkaik, N.S.6
Van Heems, D.7
Ito, E.8
Nakamura, A.9
Komatsu, K.10
-
8
-
-
0037115935
-
Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability
-
H. Tauchi, S. Matsuura, J. Kobayashi, S. Sakamoto and K. Komatsu, Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability. Oncogene 21, 8967-8980 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 8967-8980
-
-
Tauchi, H.1
Matsuura, S.2
Kobayashi, J.3
Sakamoto, S.4
Komatsu, K.5
-
9
-
-
0032562595
-
In situ visualization of DNA double-strand break repair in human fibroblasts
-
B. E. Nelms, R. S. Maser, J. F. MacKay, M. G. Lagally and J. H. Petrini, In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280, 590-592 (1998).
-
(1998)
Science
, vol.280
, pp. 590-592
-
-
Nelms, B.E.1
Maser, R.S.2
MacKay, J.F.3
Lagally, M.G.4
Petrini, J.H.5
-
10
-
-
21344452093
-
NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells
-
Y. Zhang, C. U. Lim, E. S. Williams, J. Zhou, Q. Zhang, M. H. Fox, S. M. Bailey and H. L. Liber, NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells. Cancer Res. 65, 5544-5553 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 5544-5553
-
-
Zhang, Y.1
Lim, C.U.2
Williams, E.S.3
Zhou, J.4
Zhang, Q.5
Fox, M.H.6
Bailey, S.M.7
Liber, H.L.8
-
11
-
-
0034020464
-
The Mre11 complex and ATM: Collaborating to navigate S phase
-
J. H. Petrini, The Mre11 complex and ATM: Collaborating to navigate S phase. Curr. Opin. Cell Biol. 12, 293-296 (2000).
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 293-296
-
-
Petrini, J.H.1
-
12
-
-
0031881815
-
Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells
-
K. Ohta, A. Nicolas, M. Furuse, A. Nabetani, H. Ogawa and T. Shibata, Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells. Proc. Natl. Acad. Sci. USA 95, 646-651 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 646-651
-
-
Ohta, K.1
Nicolas, A.2
Furuse, M.3
Nabetani, A.4
Ogawa, H.5
Shibata, T.6
-
13
-
-
0027156278
-
Impairment of V(D)J recombination in double-strand break repair mutants
-
G. E. Taccioli, G. Rathbun, E. Oltz, T. Stamato, P. A. Jeggo and F. W. Alt, Impairment of V(D)J recombination in double-strand break repair mutants. Science 260, 207-210 (1993).
-
(1993)
Science
, vol.260
, pp. 207-210
-
-
Taccioli, G.E.1
Rathbun, G.2
Oltz, E.3
Stamato, T.4
Jeggo, P.A.5
Alt, F.W.6
-
14
-
-
0035085624
-
Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome
-
E. Harfst, S. Cooper, S. Neubauer, L. Distel and U. Grawunder, Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome. Mol. Immunol. 37, 915-929 (2000).
-
(2000)
Mol. Immunol.
, vol.37
, pp. 915-929
-
-
Harfst, E.1
Cooper, S.2
Neubauer, S.3
Distel, L.4
Grawunder, U.5
-
15
-
-
0037112508
-
Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation
-
Y. Peng, Q. Zhang, H. Nagasawa, R. Okayasu, H. L. Liber and J. S. Bedford, Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation. Cancer Res. 62, 6400-6404 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 6400-6404
-
-
Peng, Y.1
Zhang, Q.2
Nagasawa, H.3
Okayasu, R.4
Liber, H.L.5
Bedford, J.S.6
-
16
-
-
0037382008
-
Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors
-
S. J. Collis, M. J. Swartz, W. G. Nelson and T. L. DeWeese, Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. Cancer Res. 63, 1550-1554 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 1550-1554
-
-
Collis, S.J.1
Swartz, M.J.2
Nelson, W.G.3
DeWeese, T.L.4
-
17
-
-
0025858631
-
Wild-type but not mutant TP53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication
-
J. Bargonetti, P. N. Friedman, S. E. Kern, B. Vogelstein and C. Prives, Wild-type but not mutant TP53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication. Cell 65, 1083-1091 (1991).
-
(1991)
Cell
, vol.65
, pp. 1083-1091
-
-
Bargonetti, J.1
Friedman, P.N.2
Kern, S.E.3
Vogelstein, B.4
Prives, C.5
-
18
-
-
0025815451
-
Identification of TP53 as a sequence-specific DNA-binding protein
-
S. E. Kern, K. W. Kinzler, A. Bruskin, D. Jarosz, P. Friedman, C. Prives and B. Vogelstein, Identification of TP53 as a sequence-specific DNA-binding protein. Science 252, 1708-1711 (1991).
-
(1991)
Science
, vol.252
, pp. 1708-1711
-
-
Kern, S.E.1
Kinzler, K.W.2
Bruskin, A.3
Jarosz, D.4
Friedman, P.5
Prives, C.6
Vogelstein, B.7
-
19
-
-
0035160889
-
The effects of TP53 status and human papillomavirus infection on the clinical outcome of patients with stage UIB cervical carcinoma treated with radiation therapy alone
-
H. Ishikawa, N. Mitsuhashi, H. Sakurai, K. Maebayashi and H. Niibe, The effects of TP53 status and human papillomavirus infection on the clinical outcome of patients with stage UIB cervical carcinoma treated with radiation therapy alone. Cancer 91, 80-89 (2001).
-
(2001)
Cancer
, vol.91
, pp. 80-89
-
-
Ishikawa, H.1
Mitsuhashi, N.2
Sakurai, H.3
Maebayashi, K.4
Niibe, H.5
-
20
-
-
0032497587
-
A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB
-
S. J. Lee, A. Dimtchev, M. F. Lavin, A. Dritschilo and M. Jung, A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB. Oncogene 17, 1821-1826 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 1821-1826
-
-
Lee, S.J.1
Dimtchev, A.2
Lavin, M.F.3
Dritschilo, A.4
Jung, M.5
-
21
-
-
0036020941
-
NF-κB as a therapeutic target in cancer
-
R. Z. Orlowski and A. S. Baldwin, Jr., NF-κB as a therapeutic target in cancer. Trends Mol. Med. 8, 385-389 (2002).
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 385-389
-
-
Orlowski, R.Z.1
Baldwin Jr., A.S.2
-
22
-
-
0030810968
-
Enhanced radiosensitivity by inhibition of nuclear factor kappa B activation in human malignant glioma cells
-
N. Yamagishi, J. Miyakoshi and H. Takebe, Enhanced radiosensitivity by inhibition of nuclear factor kappa B activation in human malignant glioma cells. Int. J. Radiat. Biol. 72, 157-162 (1997).
-
(1997)
Int. J. Radiat. Biol.
, vol.72
, pp. 157-162
-
-
Yamagishi, N.1
Miyakoshi, J.2
Takebe, H.3
-
23
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
A. S. Baldwin, Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J. Clin. Invest. 107, 241-246 (2001).
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
24
-
-
0141618358
-
Differential involvement of the hMRE11/hRAD50/NBS1 complex, BRCA1 and MLH1 in NF-κB activation by camptothecin and X-ray
-
Y. Habraken, O. Jolois and J. Piette, Differential involvement of the hMRE11/hRAD50/NBS1 complex, BRCA1 and MLH1 in NF-κB activation by camptothecin and X-ray. Oncogene 22, 6090-6099 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 6090-6099
-
-
Habraken, Y.1
Jolois, O.2
Piette, J.3
-
25
-
-
0032410818
-
A novel anti-apoptosis gene: The inhibitors of apoptosis (IAPs) and their emerging role in cancer
-
E. C. LaCasse, S. Baird, R. G. Korneluk and A. E. MacKenzie, A novel anti-apoptosis gene: The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17, 3247-3259 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 3247-3259
-
-
LaCasse, E.C.1
Baird, S.2
Korneluk, R.G.3
MacKenzie, A.E.4
-
26
-
-
2542549018
-
High expression levels of x-linked inhibitor of apoptosis protein and surviving correlate with poor overall survival in childhood de novo acute myeloid leukemia
-
I. Tamm, S. Richter, D. Oltersdorf, U. Creutzig, J. Harbott, F. Scholz, L. Karawajew, W. D. Ludwig and C. Wuchter, High expression levels of x-linked inhibitor of apoptosis protein and surviving correlate with poor overall survival in childhood de novo acute myeloid leukemia. Clin. Cancer Res. 10, 3737-3744 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3737-3744
-
-
Tamm, I.1
Richter, S.2
Oltersdorf, D.3
Creutzig, U.4
Harbott, J.5
Scholz, F.6
Karawajew, L.7
Ludwig, W.D.8
Wuchter, C.9
-
27
-
-
4844231863
-
XIAP and surviving as therapeutic targets for radiation sensitization in preclinical models of lung cancer
-
C. Cao, Y. Mu, D. E. Hallahan and B. Lu, XIAP and surviving as therapeutic targets for radiation sensitization in preclinical models of lung cancer. Oncogene 23, 7047-7052 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 7047-7052
-
-
Cao, C.1
Mu, Y.2
Hallahan, D.E.3
Lu, B.4
-
28
-
-
4544326031
-
High-LET radiation enhanced apoptosis but not necrosis regardless of TP53 status
-
A. Takahashi, H. Matsumoto, K. Yuki, J. Yasumoto, A. Kajiwara, M. Aoki, Y. Furusawa, K. Ohnishi and T. Ohnishi, High-LET radiation enhanced apoptosis but not necrosis regardless of TP53 status. Int. J. Radiat. Oncol. Biol. Phys. 60, 591-597 (2004).
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.60
, pp. 591-597
-
-
Takahashi, A.1
Matsumoto, H.2
Yuki, K.3
Yasumoto, J.4
Kajiwara, A.5
Aoki, M.6
Furusawa, Y.7
Ohnishi, K.8
Ohnishi, T.9
-
29
-
-
0028898823
-
Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors
-
J. Oshima, J. Campisi, T. C. Tannock and G. M. Martin, Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors. J. Cell. Physiol. 162, 277-283 (1995).
-
(1995)
J. Cell. Physiol.
, vol.162
, pp. 277-283
-
-
Oshima, J.1
Campisi, J.2
Tannock, T.C.3
Martin, G.M.4
-
30
-
-
0035954284
-
Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit
-
V. Ranganathan, W. F. Heine, D. N. Ciccone, K. L. Rudolph, X. Wu, S. Chang, H. Hai, I. M. Ahearn, D. M. Livingston and D. T. Weaver, Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit. Curr. Biol. 11, 962-966 (2001).
-
(2001)
Curr. Biol.
, vol.11
, pp. 962-966
-
-
Ranganathan, V.1
Heine, W.F.2
Ciccone, D.N.3
Rudolph, K.L.4
Wu, X.5
Chang, S.6
Hai, H.7
Ahearn, I.M.8
Livingston, D.M.9
Weaver, D.T.10
-
31
-
-
25444455323
-
Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt
-
Y. C. Chen, Y. N. Su, P. C. Chou, W. C. Chiang, M. C. Chang, L. S. Wang, S. C. Teng and K. J. Wu, Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt. J. Biol. Chem. 280, 32505-32511 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32505-32511
-
-
Chen, Y.C.1
Su, Y.N.2
Chou, P.C.3
Chiang, W.C.4
Chang, M.C.5
Wang, L.S.6
Teng, S.C.7
Wu, K.J.8
-
32
-
-
0034538208
-
Glycerol restores TP53-dependent radiosensitivity of human head and neck cancer cells bearing mutant
-
K. Ohnishi, I. Ota, A. Takahashi and T. Ohnishi, Glycerol restores TP53-dependent radiosensitivity of human head and neck cancer cells bearing mutant. Br. J. Cancer 83, 1735-1739 (2000).
-
(2000)
Br. J. Cancer
, vol.83
, pp. 1735-1739
-
-
Ohnishi, K.1
Ota, I.2
Takahashi, A.3
Ohnishi, T.4
-
33
-
-
0036022408
-
Transfection of mutant TP53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck
-
K. Ohnishi, I. Ota, A. Takahashi, K. Yane, H. Matsumoto and T. Ohnishi, Transfection of mutant TP53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck. Apoptosis 7, 367-372 (2002).
-
(2002)
Apoptosis
, vol.7
, pp. 367-372
-
-
Ohnishi, K.1
Ota, I.2
Takahashi, A.3
Yane, K.4
Matsumoto, H.5
Ohnishi, T.6
-
34
-
-
0028318694
-
Mutant TP53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras
-
R. G. Bristow, A. Jang, J. Peacock, S. Chung, S. Benchimol and R. P. Hill, Mutant TP53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras. Oncogene 9, 1527-1536 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 1527-1536
-
-
Bristow, R.G.1
Jang, A.2
Peacock, J.3
Chung, S.4
Benchimol, S.5
Hill, R.P.6
-
35
-
-
0027246692
-
Regulation by bcl-2, c-myc, and TP53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells
-
J. Lotem and L. Sachs, Regulation by bcl-2, c-myc, and TP53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells. Cell Growth Differ. 4, 41-47 (1993).
-
(1993)
Cell Growth Differ.
, vol.4
, pp. 41-47
-
-
Lotem, J.1
Sachs, L.2
-
36
-
-
0028064322
-
Control of sensitivity to induction of apoptosis in myeloid leukemic cells by differentiation and bcl-2 dependent and independent pathways
-
J. Lotem and L. Sachs, Control of sensitivity to induction of apoptosis in myeloid leukemic cells by differentiation and bcl-2 dependent and independent pathways. Cell Growth Differ. 5, 321-327 (1994).
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 321-327
-
-
Lotem, J.1
Sachs, L.2
-
37
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type TP53 for radiosensitivity
-
A. J. McIlwrath, P. A. Vasey, G. M. Ross and R. Brown, Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type TP53 for radiosensitivity. Cancer Res. 54, 3718-3722 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 3718-3722
-
-
McIlwrath, A.J.1
Vasey, P.A.2
Ross, G.M.3
Brown, R.4
-
38
-
-
7344252500
-
Mutant TP53 protein expression interferes with TP53-independent apoptotic pathways
-
R. Li, P. D. Sutphin, D. Schwartz, D. Matas, N. Almog, R. Wolkowicz, N. Goldfinger, H. Pei, M. Prokocimer and V. Rotter, Mutant TP53 protein expression interferes with TP53-independent apoptotic pathways. Oncogene 16, 3269-3277 (1998).
-
(1998)
Oncogene
, vol.16
, pp. 3269-3277
-
-
Li, R.1
Sutphin, P.D.2
Schwartz, D.3
Matas, D.4
Almog, N.5
Wolkowicz, R.6
Goldfinger, N.7
Pei, H.8
Prokocimer, M.9
Rotter, V.10
|