메뉴 건너뛰기




Volumn 22, Issue 4, 2007, Pages 1041-1051

Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor-γ in human proximal renal tubular cells

Author keywords

HIF 1 ; Human proximal tubular cells; Hypoxia, MCP 1; PPAR; TNF

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 2 CHLORO 5 NITROBENZANILIDE; COMPLEMENTARY DNA; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 34047128688     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfl766     Document Type: Article
Times cited : (34)

References (38)
  • 1
    • 0034037110 scopus 로고    scopus 로고
    • Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia
    • Fine LG, Bandyopadhay D, Norman JT. Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia. Kidney Int Suppl 2000; 75: S22-S26
    • (2000) Kidney Int Suppl , vol.75
    • Fine, L.G.1    Bandyopadhay, D.2    Norman, J.T.3
  • 2
    • 0034006016 scopus 로고    scopus 로고
    • HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
    • Semenza GL. HIF-1: Mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 2000; 88: 1474-1480
    • (2000) J Appl Physiol , vol.88 , pp. 1474-1480
    • Semenza, G.L.1
  • 3
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P, Mole DR, Tian YM et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001; 292: 468-472
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3
  • 4
    • 0034951366 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Novel therapeutic targets in renal disease
    • Guan Y, Breyer MD. Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease. Kidney Int 2001; 60: 14-30
    • (2001) Kidney Int , vol.60 , pp. 14-30
    • Guan, Y.1    Breyer, M.D.2
  • 5
    • 16644377741 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome
    • Guan Y. Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome. J Am Soc Nephrol 2004; 15: 2801-2815
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2801-2815
    • Guan, Y.1
  • 6
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391: 82-86
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 8
    • 4143099046 scopus 로고    scopus 로고
    • The effect of high glucose and PPAR-gamma agonists on PPAR-gamma expression and function in HK-2 cells
    • Panchapakesan U, Pollock CA, Chen XM. The effect of high glucose and PPAR-gamma agonists on PPAR-gamma expression and function in HK-2 cells. Am J Physiol Renal Physiol 2004; 287: F528-F534
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Panchapakesan, U.1    Pollock, C.A.2    Chen, X.M.3
  • 9
    • 20844440063 scopus 로고    scopus 로고
    • EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-gamma-dependent mechanism
    • Li H, Ruan XZ, Powis SH et al. EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-gamma-dependent mechanism. Kidney Int 2005; 67: 867-874
    • (2005) Kidney Int , vol.67 , pp. 867-874
    • Li, H.1    Ruan, X.Z.2    Powis, S.H.3
  • 10
    • 33645454825 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-γ agonists
    • Li Y, Wen X, Spataro BC, Hu K, Dai C, Liu Y. Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-γ agonists. J Am Soc Nephrol 2006; 17: 54-65
    • (2006) J Am Soc Nephrol , vol.17 , pp. 54-65
    • Li, Y.1    Wen, X.2    Spataro, B.C.3    Hu, K.4    Dai, C.5    Liu, Y.6
  • 11
    • 0035877163 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia
    • Narravula S, Colgan SP. Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia. J Immunol 2001; 166: 7543-7548
    • (2001) J Immunol , vol.166 , pp. 7543-7548
    • Narravula, S.1    Colgan, S.P.2
  • 12
    • 0036198010 scopus 로고    scopus 로고
    • Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: A mechanism for regulation of adipogenesis by hypoxia
    • Yun Z, Maecker HL, Johnson RS, Giaccia AJ. Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: A mechanism for regulation of adipogenesis by hypoxia. Dev Cell 2002; 2: 331-341
    • (2002) Dev Cell , vol.2 , pp. 331-341
    • Yun, Z.1    Maecker, H.L.2    Johnson, R.S.3    Giaccia, A.J.4
  • 13
    • 32844463572 scopus 로고    scopus 로고
    • In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species
    • Kwan J, Wang H, Munk S, Xia L, Goldberg HJ, Whiteside CI. In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species. Kidney Int 2005; 68: 2526-2541
    • (2005) Kidney Int , vol.68 , pp. 2526-2541
    • Kwan, J.1    Wang, H.2    Munk, S.3    Xia, L.4    Goldberg, H.J.5    Whiteside, C.I.6
  • 14
    • 24044551817 scopus 로고    scopus 로고
    • Synergistic effect of hypoxia and tumor necrosis factor-α on production of plasminogen activator inhibitor-1 in human proximal renal tubular cells
    • Li X, Kimura H, Hirota K et al. Synergistic effect of hypoxia and tumor necrosis factor-α on production of plasminogen activator inhibitor-1 in human proximal renal tubular cells. Kidney Int 2005; 68: 569-583
    • (2005) Kidney Int , vol.68 , pp. 569-583
    • Li, X.1    Kimura, H.2    Hirota, K.3
  • 15
    • 1642453685 scopus 로고    scopus 로고
    • Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling
    • Kasuno K, Takabuchi S, Fukuda K et al. Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling. J Biol Chem 2004; 279: 2550-2558
    • (2004) J Biol Chem , vol.279 , pp. 2550-2558
    • Kasuno, K.1    Takabuchi, S.2    Fukuda, K.3
  • 16
    • 25644443217 scopus 로고    scopus 로고
    • Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis
    • Fiorucci S, Rizzo G, Antonelli E et al. Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis. J Pharmacol Exp Ther 2005; 315: 58-68
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 58-68
    • Fiorucci, S.1    Rizzo, G.2    Antonelli, E.3
  • 17
    • 0034916165 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells
    • Rovin BH, Lu L, Cosio A. Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells. J Am Soc Nephrol 2001; 12: 1659-1667
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1659-1667
    • Rovin, B.H.1    Lu, L.2    Cosio, A.3
  • 18
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 2001; 7: 48-52
    • (2001) Nat Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 19
    • 0034595727 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation
    • Asano T, Wakisaka M, Yoshinari M et al. Peroxisome proliferator-activated receptor gamma1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation. Biochim Biophys Acta 2000; 1497: 148-154
    • (2000) Biochim Biophys Acta , vol.1497 , pp. 148-154
    • Asano, T.1    Wakisaka, M.2    Yoshinari, M.3
  • 20
    • 0030977450 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
    • Vidal-Puig AJ, Considine RV, Jimenez-Linan M et al. Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest 1997; 99: 2416-2422
    • (1997) J Clin Invest , vol.99 , pp. 2416-2422
    • Vidal-Puig, A.J.1    Considine, R.V.2    Jimenez-Linan, M.3
  • 21
    • 0031037988 scopus 로고    scopus 로고
    • Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcription
    • Schwarz EJ, Reginato MJ, Shao D, Krakow SL, Lazar MA. Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcription. Mol Cell Biol 1997; 17: 1552-1561
    • (1997) Mol Cell Biol , vol.17 , pp. 1552-1561
    • Schwarz, E.J.1    Reginato, M.J.2    Shao, D.3    Krakow, S.L.4    Lazar, M.A.5
  • 22
    • 0030458404 scopus 로고    scopus 로고
    • Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha
    • Zhang B, Berger J, Hu E et al. Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha. Mol Endocrinol 1996; 10: 1457-1466
    • (1996) Mol Endocrinol , vol.10 , pp. 1457-1466
    • Zhang, B.1    Berger, J.2    Hu, E.3
  • 23
    • 0037414757 scopus 로고    scopus 로고
    • Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation
    • Zhang Y, Kast-Woelbern HR, Edwards PA. Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation. J Biol Chem 2003; 278: 104-110
    • (2003) J Biol Chem , vol.278 , pp. 104-110
    • Zhang, Y.1    Kast-Woelbern, H.R.2    Edwards, P.A.3
  • 24
  • 25
    • 0034613375 scopus 로고    scopus 로고
    • Function of GATA transcription factors in preadipocyte-adipocyte transition
    • Tong Q, Dalgin G, Xu H, Ting CN, Leiden JM, Hotamisligil GS. Function of GATA transcription factors in preadipocyte-adipocyte transition. Science 2000; 290: 134-138
    • (2000) Science , vol.290 , pp. 134-138
    • Tong, Q.1    Dalgin, G.2    Xu, H.3    Ting, C.N.4    Leiden, J.M.5    Hotamisligil, G.S.6
  • 26
    • 0038025936 scopus 로고    scopus 로고
    • Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia
    • Schafer M, Schafer C, Ewald N, Piper HM, Noll T. Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia. Circ Res 2003; 92: 1010-1015
    • (2003) Circ Res , vol.92 , pp. 1010-1015
    • Schafer, M.1    Schafer, C.2    Ewald, N.3    Piper, H.M.4    Noll, T.5
  • 27
    • 26844496791 scopus 로고    scopus 로고
    • PPARgamma agonists exert antifibrotic effects in renal tubular cells exposed to high glucose
    • Panchapakesan U, Sumual S, Pollock CA, Chen X. PPARgamma agonists exert antifibrotic effects in renal tubular cells exposed to high glucose. Am J Physiol Renal Physiol 2005; 289: F1153-F1158
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Panchapakesan, U.1    Sumual, S.2    Pollock, C.A.3    Chen, X.4
  • 28
    • 2342473267 scopus 로고    scopus 로고
    • Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and fibrotic responses
    • Zafiriou S, Stanners SR, Polhill TS, Poronnik P, Pollock CA. Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and fibrotic responses. Kidney Int 2004; 65: 1647-1653
    • (2004) Kidney Int , vol.65 , pp. 1647-1653
    • Zafiriou, S.1    Stanners, S.R.2    Polhill, T.S.3    Poronnik, P.4    Pollock, C.A.5
  • 29
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391: 79-82
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 30
    • 9644295737 scopus 로고    scopus 로고
    • Ligand-independent activation of peroxisome proliferator-activated receptor-gamma by insulin and C-peptide in kidney proximal tubular cells: Dependent on phosphatidylinositol 3-kinase activity
    • Al-Rasheed NM, Chana RS, Baines RJ, Willars GB, Brunskill NJ. Ligand-independent activation of peroxisome proliferator-activated receptor-gamma by insulin and C-peptide in kidney proximal tubular cells: Dependent on phosphatidylinositol 3-kinase activity. J Biol Chem 2004; 279: 49747-49754
    • (2004) J Biol Chem , vol.279 , pp. 49747-49754
    • Al-Rasheed, N.M.1    Chana, R.S.2    Baines, R.J.3    Willars, G.B.4    Brunskill, N.J.5
  • 31
    • 27644452273 scopus 로고    scopus 로고
    • Differential responses of PPARalpha, PPARdelta and PPARgamma reporter cell lines to selective PPAR synthetic ligands
    • Seimandi M, Lemaire G, Pillon A et al. Differential responses of PPARalpha, PPARdelta and PPARgamma reporter cell lines to selective PPAR synthetic ligands. Anal Biochem 2005; 344: 8-15
    • (2005) Anal Biochem , vol.344 , pp. 8-15
    • Seimandi, M.1    Lemaire, G.2    Pillon, A.3
  • 32
    • 18444412555 scopus 로고    scopus 로고
    • Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662
    • Leesnitzer LM, Parks DJ, Bledsoe RK et al. Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662. Biochemistry 2002; 41: 6640-6650
    • (2002) Biochemistry , vol.41 , pp. 6640-6650
    • Leesnitzer, L.M.1    Parks, D.J.2    Bledsoe, R.K.3
  • 34
    • 0028032360 scopus 로고
    • Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2)
    • Koong AC, Chen EY, Mivechi NF, Denko NC, Stambrook P, Giaccia AJ. Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2). Cancer Res 1994; 54: 5273-5279
    • (1994) Cancer Res , vol.54 , pp. 5273-5279
    • Koong, A.C.1    Chen, E.Y.2    Mivechi, N.F.3    Denko, N.C.4    Stambrook, P.5    Giaccia, A.J.6
  • 35
    • 0031590460 scopus 로고    scopus 로고
    • Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes
    • Seko Y, Takahashi N, Tobe K, Kadowaki T, Yazaki Y. Hypoxia and hypoxia/ reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes. Biochem Biophys Res Commun 1997; 239: 840-844
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 840-844
    • Seko, Y.1    Takahashi, N.2    Tobe, K.3    Kadowaki, T.4    Yazaki, Y.5
  • 36
    • 1642525769 scopus 로고    scopus 로고
    • Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages
    • Bosco MC, Puppo M, Pastorino S et al. Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages. J Immunol 2004; 172: 1681-1690
    • (2004) J Immunol , vol.172 , pp. 1681-1690
    • Bosco, M.C.1    Puppo, M.2    Pastorino, S.3
  • 37
    • 24044527480 scopus 로고    scopus 로고
    • Hypoxia reduces constitutive and TNF-alpha-induced expression of monocyte chemoattractant protein-1 in human proximal renal tubular cells
    • Li X, Kimura H, Hirota K, Sugimoto H, Yoshida H. Hypoxia reduces constitutive and TNF-alpha-induced expression of monocyte chemoattractant protein-1 in human proximal renal tubular cells. Biochem Biophys Res Commun 2005; 335: 1026-1034
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 1026-1034
    • Li, X.1    Kimura, H.2    Hirota, K.3    Sugimoto, H.4    Yoshida, H.5
  • 38
    • 0344084233 scopus 로고    scopus 로고
    • Effect of hypoxia on monocyte chemotactic protein-1 (MCP-1) gene expression induced by Interleukin-1beta in human synovial fibroblasts
    • Safronova O, Nakahama K, Onodera M, Muneta T, Morita I. Effect of hypoxia on monocyte chemotactic protein-1 (MCP-1) gene expression induced by Interleukin-1beta in human synovial fibroblasts. Inflamm Res 2003; 52: 480-486
    • (2003) Inflamm Res , vol.52 , pp. 480-486
    • Safronova, O.1    Nakahama, K.2    Onodera, M.3    Muneta, T.4    Morita, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.