-
1
-
-
2042493330
-
In vitro experiments on the effects of mouse sarcomas 180 and 37 on the spinal and sympathetic ganglia of the chick embryo
-
Levi-Montalcini R., Meyer H., and Hamburger V. In vitro experiments on the effects of mouse sarcomas 180 and 37 on the spinal and sympathetic ganglia of the chick embryo. Cancer Res 14 1 (1954) 49-57
-
(1954)
Cancer Res
, vol.14
, Issue.1
, pp. 49-57
-
-
Levi-Montalcini, R.1
Meyer, H.2
Hamburger, V.3
-
2
-
-
0036581222
-
The GDNF family: signalling, biological functions and therapeutic value
-
Airaksinen M.S., and Saarma M. The GDNF family: signalling, biological functions and therapeutic value. Nat Rev Neurosci 3 5 (2002) 383-394
-
(2002)
Nat Rev Neurosci
, vol.3
, Issue.5
, pp. 383-394
-
-
Airaksinen, M.S.1
Saarma, M.2
-
3
-
-
0028592625
-
Neurotrophins and receptors
-
Lindsay R.M. Neurotrophins and receptors. Prog Brain Res 103 (1994) 3-14
-
(1994)
Prog Brain Res
, vol.103
, pp. 3-14
-
-
Lindsay, R.M.1
-
4
-
-
0027972153
-
Neurotrophic factor therapy for nervous system degenerative diseases
-
Hefti F. Neurotrophic factor therapy for nervous system degenerative diseases. J Neurobiol 25 11 (1994) 1418-1435
-
(1994)
J Neurobiol
, vol.25
, Issue.11
, pp. 1418-1435
-
-
Hefti, F.1
-
5
-
-
0020338405
-
Purification of a new neurotrophic factor from mammalian brain
-
Barde Y.A., Edgar D., and Thoenen H. Purification of a new neurotrophic factor from mammalian brain. EMBO J 1 5 (1982) 549-553
-
(1982)
EMBO J
, vol.1
, Issue.5
, pp. 549-553
-
-
Barde, Y.A.1
Edgar, D.2
Thoenen, H.3
-
6
-
-
33749010358
-
Neurotrophin-regulated signalling pathways
-
Reichardt L.F. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 361 1473 (2006) 1545-1564
-
(2006)
Philos Trans R Soc Lond B Biol Sci
, vol.361
, Issue.1473
, pp. 1545-1564
-
-
Reichardt, L.F.1
-
7
-
-
0031562357
-
Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system
-
Yan Q., Rosenfeld R.D., Matheson C.R., Hawkins N., Lopez O.T., Bennett L., et al. Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system. Neuroscience 78 2 (1997) 431-448
-
(1997)
Neuroscience
, vol.78
, Issue.2
, pp. 431-448
-
-
Yan, Q.1
Rosenfeld, R.D.2
Matheson, C.R.3
Hawkins, N.4
Lopez, O.T.5
Bennett, L.6
-
8
-
-
0031017680
-
Immunocytochemical localization of TrkB in the central nervous system of the adult rat
-
Yan Q., Radeke M.J., Matheson C.R., Talvenheimo J., Welcher A.A., and Feinstein S.C. Immunocytochemical localization of TrkB in the central nervous system of the adult rat. J Comp Neurol 378 1 (1997) 135-157
-
(1997)
J Comp Neurol
, vol.378
, Issue.1
, pp. 135-157
-
-
Yan, Q.1
Radeke, M.J.2
Matheson, C.R.3
Talvenheimo, J.4
Welcher, A.A.5
Feinstein, S.C.6
-
9
-
-
0033602009
-
Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra
-
Parain K., Murer M.G., Yan Q., Faucheux B., Agid Y., Hirsch E., et al. Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra. Neuroreport 10 3 (1999) 557-561
-
(1999)
Neuroreport
, vol.10
, Issue.3
, pp. 557-561
-
-
Parain, K.1
Murer, M.G.2
Yan, Q.3
Faucheux, B.4
Agid, Y.5
Hirsch, E.6
-
10
-
-
33745000075
-
Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease
-
Zhang X., Andren P.E., and Svenningsson P. Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease. Brain Res 1095 1 (2006) 207-210
-
(2006)
Brain Res
, vol.1095
, Issue.1
, pp. 207-210
-
-
Zhang, X.1
Andren, P.E.2
Svenningsson, P.3
-
11
-
-
77952091883
-
Regulation of brain-derived neurotrophic factor (BDNF) and cerebral dopamine neurotrophic factor (CDNF) by anti-parkinsonian drug therapy in vivo
-
Gyarfas T., Knuuttila J., Lindholm P., Rantamaki T., and Castren E. Regulation of brain-derived neurotrophic factor (BDNF) and cerebral dopamine neurotrophic factor (CDNF) by anti-parkinsonian drug therapy in vivo. Cell Mol Neurobiol (2009)
-
(2009)
Cell Mol Neurobiol
-
-
Gyarfas, T.1
Knuuttila, J.2
Lindholm, P.3
Rantamaki, T.4
Castren, E.5
-
12
-
-
71549124927
-
Modulation of brain-derived neurotrophic factor as a potential neuroprotective mechanism of action of omega-3 fatty acids in a parkinsonian animal model
-
Bousquet M., Gibrat C., Saint-Pierre M., Julien C., Calon F., and Cicchetti F. Modulation of brain-derived neurotrophic factor as a potential neuroprotective mechanism of action of omega-3 fatty acids in a parkinsonian animal model. Prog Neuropsychopharmacol Biol Psychiatry (2009)
-
(2009)
Prog Neuropsychopharmacol Biol Psychiatry
-
-
Bousquet, M.1
Gibrat, C.2
Saint-Pierre, M.3
Julien, C.4
Calon, F.5
Cicchetti, F.6
-
13
-
-
0029610630
-
Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease
-
Levivier M., Przedborski S., Bencsics C., and Kang U.J. Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. J Neurosci 15 12 (1995) 7810-7820
-
(1995)
J Neurosci
, vol.15
, Issue.12
, pp. 7810-7820
-
-
Levivier, M.1
Przedborski, S.2
Bencsics, C.3
Kang, U.J.4
-
14
-
-
0028276809
-
Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat
-
Frim D.M., Uhler T.A., Galpern W.R., Beal M.F., Breakefield X.O., and Isacson O. Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc Natl Acad Sci USA 91 11 (1994) 5104-5108
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.11
, pp. 5104-5108
-
-
Frim, D.M.1
Uhler, T.A.2
Galpern, W.R.3
Beal, M.F.4
Breakefield, X.O.5
Isacson, O.6
-
15
-
-
0032704605
-
Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer
-
Klein R.L., Lewis M.H., Muzyczka N., and Meyer E.M. Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer. Brain Res 847 2 (1999) 314-320
-
(1999)
Brain Res
, vol.847
, Issue.2
, pp. 314-320
-
-
Klein, R.L.1
Lewis, M.H.2
Muzyczka, N.3
Meyer, E.M.4
-
16
-
-
0029103262
-
Effects of brain-derived neurotrophic factor on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in monkeys
-
Tsukahara T., Takeda M., Shimohama S., Ohara O., and Hashimoto N. Effects of brain-derived neurotrophic factor on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in monkeys. Neurosurgery 37 4 (1995) 733-739
-
(1995)
Neurosurgery
, vol.37
, Issue.4
, pp. 733-739
-
-
Tsukahara, T.1
Takeda, M.2
Shimohama, S.3
Ohara, O.4
Hashimoto, N.5
-
17
-
-
0037942718
-
MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons
-
Petrova P., Raibekas A., Pevsner J., Vigo N., Anafi M., Moore M.K., et al. MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci 20 2 (2003) 173-188
-
(2003)
J Mol Neurosci
, vol.20
, Issue.2
, pp. 173-188
-
-
Petrova, P.1
Raibekas, A.2
Pevsner, J.3
Vigo, N.4
Anafi, M.5
Moore, M.K.6
-
18
-
-
33644509266
-
Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release
-
Zhou C., Xiao C., Commissiong J.W., Krnjevic K., and Ye J.H. Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release. Neuroreport 17 3 (2006) 293-297
-
(2006)
Neuroreport
, vol.17
, Issue.3
, pp. 293-297
-
-
Zhou, C.1
Xiao, C.2
Commissiong, J.W.3
Krnjevic, K.4
Ye, J.H.5
-
19
-
-
68049127516
-
Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease
-
Voutilainen M.H., Back S., Porsti E., Toppinen L., Lindgren L., Lindholm P., et al. Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease. J Neurosci 29 30 (2009) 9651-9659
-
(2009)
J Neurosci
, vol.29
, Issue.30
, pp. 9651-9659
-
-
Voutilainen, M.H.1
Back, S.2
Porsti, E.3
Toppinen, L.4
Lindgren, L.5
Lindholm, P.6
-
20
-
-
0027285510
-
GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
-
Lin L.F., Doherty D.H., Lile J.D., Bektesh S., and Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260 5111 (1993) 1130-1132
-
(1993)
Science
, vol.260
, Issue.5111
, pp. 1130-1132
-
-
Lin, L.F.1
Doherty, D.H.2
Lile, J.D.3
Bektesh, S.4
Collins, F.5
-
21
-
-
46049095244
-
Absolute requirement of GDNF for adult catecholaminergic neuron survival
-
Pascual A., Hidalgo-Figueroa M., Piruat J.I., Pintado C.O., Gomez-Diaz R., and Lopez-Barneo J. Absolute requirement of GDNF for adult catecholaminergic neuron survival. Nat Neurosci 11 7 (2008) 755-761
-
(2008)
Nat Neurosci
, vol.11
, Issue.7
, pp. 755-761
-
-
Pascual, A.1
Hidalgo-Figueroa, M.2
Piruat, J.I.3
Pintado, C.O.4
Gomez-Diaz, R.5
Lopez-Barneo, J.6
-
22
-
-
0032125462
-
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
-
Horger B.A., Nishimura M.C., Armanini M.P., Wang L.C., Poulsen K.T., Rosenblad C., et al. Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. J Neurosci 18 13 (1998) 4929-4937
-
(1998)
J Neurosci
, vol.18
, Issue.13
, pp. 4929-4937
-
-
Horger, B.A.1
Nishimura, M.C.2
Armanini, M.P.3
Wang, L.C.4
Poulsen, K.T.5
Rosenblad, C.6
-
23
-
-
15844418441
-
Characterization of a multicomponent receptor for GDNF
-
Treanor J.J., Goodman L., de Sauvage F., Stone D.M., Poulsen K.T., Beck C.D., et al. Characterization of a multicomponent receptor for GDNF. Nature 382 6586 (1996) 80-83
-
(1996)
Nature
, vol.382
, Issue.6586
, pp. 80-83
-
-
Treanor, J.J.1
Goodman, L.2
de Sauvage, F.3
Stone, D.M.4
Poulsen, K.T.5
Beck, C.D.6
-
24
-
-
15844406351
-
Functional receptor for GDNF encoded by the c-ret proto-oncogene
-
Trupp M., Arenas E., Fainzilber M., Nilsson A.S., Sieber B.A., Grigoriou M., et al. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381 6585 (1996) 785-789
-
(1996)
Nature
, vol.381
, Issue.6585
, pp. 785-789
-
-
Trupp, M.1
Arenas, E.2
Fainzilber, M.3
Nilsson, A.S.4
Sieber, B.A.5
Grigoriou, M.6
-
25
-
-
0037105817
-
Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease
-
Marco S., Saura J., Perez-Navarro E., Jose M.M., Tolosa E., and Alberch J. Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease. J Neurobiol 52 4 (2002) 343-351
-
(2002)
J Neurobiol
, vol.52
, Issue.4
, pp. 343-351
-
-
Marco, S.1
Saura, J.2
Perez-Navarro, E.3
Jose, M.M.4
Tolosa, E.5
Alberch, J.6
-
26
-
-
0029846514
-
Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase
-
Worby C.A., Vega Q.C., Zhao Y., Chao H.H., Seasholtz A.F., and Dixon J.E. Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase. J Biol Chem 271 39 (1996) 23619-23622
-
(1996)
J Biol Chem
, vol.271
, Issue.39
, pp. 23619-23622
-
-
Worby, C.A.1
Vega, Q.C.2
Zhao, Y.3
Chao, H.H.4
Seasholtz, A.F.5
Dixon, J.E.6
-
27
-
-
0032241463
-
Signal transduction by the receptor tyrosine kinase Ret
-
van Weering D.H., and Bos J.L. Signal transduction by the receptor tyrosine kinase Ret. Recent Results Cancer Res 154 (1998) 271-281
-
(1998)
Recent Results Cancer Res
, vol.154
, pp. 271-281
-
-
van Weering, D.H.1
Bos, J.L.2
-
28
-
-
9244251611
-
The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma
-
Borrello M.G., Alberti L., Arighi E., Bongarzone I., Battistini C., Bardelli A., et al. The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma. Mol Cell Biol 16 5 (1996) 2151-2163
-
(1996)
Mol Cell Biol
, vol.16
, Issue.5
, pp. 2151-2163
-
-
Borrello, M.G.1
Alberti, L.2
Arighi, E.3
Bongarzone, I.4
Battistini, C.5
Bardelli, A.6
-
29
-
-
0028874203
-
GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo
-
Kearns C.M., and Gash D.M. GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo. Brain Res 672 1-2 (1995) 104-111
-
(1995)
Brain Res
, vol.672
, Issue.1-2
, pp. 104-111
-
-
Kearns, C.M.1
Gash, D.M.2
-
30
-
-
0029047329
-
Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion
-
Sauer H., Rosenblad C., and Bjorklund A. Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc Natl Acad Sci USA 92 19 (1995) 8935-8939
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.19
, pp. 8935-8939
-
-
Sauer, H.1
Rosenblad, C.2
Bjorklund, A.3
-
31
-
-
0033773237
-
Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor
-
Kirik D., Rosenblad C., and Bjorklund A. Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor. Eur J Neurosci 12 11 (2000) 3871-3882
-
(2000)
Eur J Neurosci
, vol.12
, Issue.11
, pp. 3871-3882
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
-
32
-
-
0037911432
-
Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects
-
Ai Y., Markesbery W., Zhang Z., Grondin R., Elseberry D., Gerhardt G.A., et al. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. J Comp Neurol 461 2 (2003) 250-261
-
(2003)
J Comp Neurol
, vol.461
, Issue.2
, pp. 250-261
-
-
Ai, Y.1
Markesbery, W.2
Zhang, Z.3
Grondin, R.4
Elseberry, D.5
Gerhardt, G.A.6
-
33
-
-
0036751973
-
Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged Rhesus monkeys
-
Maswood N., Grondin R., Zhang Z., Stanford J.A., Surgener S.P., Gash D.M., et al. Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged Rhesus monkeys. Neurobiol Aging 23 5 (2002) 881-889
-
(2002)
Neurobiol Aging
, vol.23
, Issue.5
, pp. 881-889
-
-
Maswood, N.1
Grondin, R.2
Zhang, Z.3
Stanford, J.A.4
Surgener, S.P.5
Gash, D.M.6
-
34
-
-
0036787532
-
Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
-
Grondin R., Zhang Z., Yi A., Cass W.A., Maswood N., Andersen A.H., et al. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain 125 Pt 10 (2002) 2191-2201
-
(2002)
Brain
, vol.125
, Issue.PART 10
, pp. 2191-2201
-
-
Grondin, R.1
Zhang, Z.2
Yi, A.3
Cass, W.A.4
Maswood, N.5
Andersen, A.H.6
-
35
-
-
0037199818
-
Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease
-
Oiwa Y., Yoshimura R., Nakai K., and Itakura T. Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease. Brain Res 947 2 (2002) 271-283
-
(2002)
Brain Res
, vol.947
, Issue.2
, pp. 271-283
-
-
Oiwa, Y.1
Yoshimura, R.2
Nakai, K.3
Itakura, T.4
-
36
-
-
44149098643
-
Intraputamenal infusion of exogenous neurturin protein restores motor and dopaminergic function in the globus pallidus of MPTP-lesioned rhesus monkeys
-
Grondin R., Zhang Z., Ai Y., Ding F., Walton A.A., Surgener S.P., et al. Intraputamenal infusion of exogenous neurturin protein restores motor and dopaminergic function in the globus pallidus of MPTP-lesioned rhesus monkeys. Cell Transplant 17 4 (2008) 373-381
-
(2008)
Cell Transplant
, vol.17
, Issue.4
, pp. 373-381
-
-
Grondin, R.1
Zhang, Z.2
Ai, Y.3
Ding, F.4
Walton, A.A.5
Surgener, S.P.6
-
37
-
-
0032939002
-
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle
-
Rosenblad C., Kirik D., Devaux B., Moffat B., Phillips H.S., and Bjorklund A. Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle. Eur J Neurosci 11 5 (1999) 1554-1566
-
(1999)
Eur J Neurosci
, vol.11
, Issue.5
, pp. 1554-1566
-
-
Rosenblad, C.1
Kirik, D.2
Devaux, B.3
Moffat, B.4
Phillips, H.S.5
Bjorklund, A.6
-
38
-
-
0031019795
-
Dopaminergic neurons protected from degeneration by GDNF gene therapy
-
Choi-Lundberg D.L., Lin Q., Chang Y.N., Chiang Y.L., Hay C.M., Mohajeri H., et al. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science 275 5301 (1997) 838-841
-
(1997)
Science
, vol.275
, Issue.5301
, pp. 838-841
-
-
Choi-Lundberg, D.L.1
Lin, Q.2
Chang, Y.N.3
Chiang, Y.L.4
Hay, C.M.5
Mohajeri, H.6
-
39
-
-
0030795798
-
Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
-
Bilang-Bleuel A., Revah F., Colin P., Locquet I., Robert J.J., Mallet J., et al. Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc Natl Acad Sci USA 94 16 (1997) 8818-8823
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.16
, pp. 8818-8823
-
-
Bilang-Bleuel, A.1
Revah, F.2
Colin, P.3
Locquet, I.4
Robert, J.J.5
Mallet, J.6
-
40
-
-
0034659835
-
Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system
-
Kirik D., Rosenblad C., Bjorklund A., and Mandel R.J. Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system. J Neurosci 20 12 (2000) 4686-4700
-
(2000)
J Neurosci
, vol.20
, Issue.12
, pp. 4686-4700
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
Mandel, R.J.4
-
41
-
-
33846011117
-
Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease
-
Gasmi M., Herzog C.D., Brandon E.P., Cunningham J.J., Ramirez G.A., Ketchum E.T., et al. Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease. Mol Ther 15 1 (2007) 62-68
-
(2007)
Mol Ther
, vol.15
, Issue.1
, pp. 62-68
-
-
Gasmi, M.1
Herzog, C.D.2
Brandon, E.P.3
Cunningham, J.J.4
Ramirez, G.A.5
Ketchum, E.T.6
-
42
-
-
34250336916
-
AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease
-
Gasmi M., Brandon E.P., Herzog C.D., Wilson A., Bishop K.M., Hofer E.K., et al. AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease. Neurobiol Dis 27 1 (2007) 67-76
-
(2007)
Neurobiol Dis
, vol.27
, Issue.1
, pp. 67-76
-
-
Gasmi, M.1
Brandon, E.P.2
Herzog, C.D.3
Wilson, A.4
Bishop, K.M.5
Hofer, E.K.6
-
43
-
-
0345257314
-
Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus)
-
Eslamboli A., Cummings R.M., Ridley R.M., Baker H.F., Muzyczka N., Burger C., et al. Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus). Exp Neurol 184 1 (2003) 536-548
-
(2003)
Exp Neurol
, vol.184
, Issue.1
, pp. 536-548
-
-
Eslamboli, A.1
Cummings, R.M.2
Ridley, R.M.3
Baker, H.F.4
Muzyczka, N.5
Burger, C.6
-
44
-
-
85047698430
-
Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease
-
Wang L., Muramatsu S., Lu Y., Ikeguchi K., Fujimoto K., Okada T., et al. Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease. Gene Ther 9 6 (2002) 381-389
-
(2002)
Gene Ther
, vol.9
, Issue.6
, pp. 381-389
-
-
Wang, L.1
Muramatsu, S.2
Lu, Y.3
Ikeguchi, K.4
Fujimoto, K.5
Okada, T.6
-
45
-
-
33845993229
-
Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys
-
Kordower J.H., Herzog C.D., Dass B., Bakay R.A., Stansell III J., Gasmi M., et al. Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Ann Neurol 60 6 (2006) 706-715
-
(2006)
Ann Neurol
, vol.60
, Issue.6
, pp. 706-715
-
-
Kordower, J.H.1
Herzog, C.D.2
Dass, B.3
Bakay, R.A.4
Stansell III, J.5
Gasmi, M.6
-
46
-
-
0037435511
-
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
-
Nutt J.G., Burchiel K.J., Comella C.L., Jankovic J., Lang A.E., Laws Jr. E.R., et al. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 60 1 (2003) 69-73
-
(2003)
Neurology
, vol.60
, Issue.1
, pp. 69-73
-
-
Nutt, J.G.1
Burchiel, K.J.2
Comella, C.L.3
Jankovic, J.4
Lang, A.E.5
Laws Jr., E.R.6
-
47
-
-
34047220707
-
Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal
-
Slevin J.T., Gash D.M., Smith C.D., Gerhardt G.A., Kryscio R., Chebrolu H., et al. Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal. J Neurosurg 106 4 (2007) 614-620
-
(2007)
J Neurosurg
, vol.106
, Issue.4
, pp. 614-620
-
-
Slevin, J.T.1
Gash, D.M.2
Smith, C.D.3
Gerhardt, G.A.4
Kryscio, R.5
Chebrolu, H.6
-
48
-
-
0032850453
-
Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease
-
Kordower J.H., Palfi S., Chen E.Y., Ma S.Y., Sendera T., Cochran E.J., et al. Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease. Ann Neurol 46 3 (1999) 419-424
-
(1999)
Ann Neurol
, vol.46
, Issue.3
, pp. 419-424
-
-
Kordower, J.H.1
Palfi, S.2
Chen, E.Y.3
Ma, S.Y.4
Sendera, T.5
Cochran, E.J.6
-
49
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill S.S., Patel N.K., Hotton G.R., O'Sullivan K., McCarter R., Bunnage M., et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 9 5 (2003) 589-595
-
(2003)
Nat Med
, vol.9
, Issue.5
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
O'Sullivan, K.4
McCarter, R.5
Bunnage, M.6
-
50
-
-
13144282676
-
Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study
-
Patel N.K., Bunnage M., Plaha P., Svendsen C.N., Heywood P., and Gill S.S. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study. Ann Neurol 57 2 (2005) 298-302
-
(2005)
Ann Neurol
, vol.57
, Issue.2
, pp. 298-302
-
-
Patel, N.K.1
Bunnage, M.2
Plaha, P.3
Svendsen, C.N.4
Heywood, P.5
Gill, S.S.6
-
51
-
-
41949110690
-
Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
-
Marks Jr. W.J., Ostrem J.L., Verhagen L., Starr P.A., Larson P.S., Bakay R.A., et al. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol 7 5 (2008) 400-408
-
(2008)
Lancet Neurol
, vol.7
, Issue.5
, pp. 400-408
-
-
Marks Jr., W.J.1
Ostrem, J.L.2
Verhagen, L.3
Starr, P.A.4
Larson, P.S.5
Bakay, R.A.6
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